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Literature DB >> 1605619

Inhibition of norfloxacin absorption by dairy products.

K T Kivistö¹, P Ojala-Karlsson, P J Neuvonen.

Abstract

Seven healthy subjects received, after an overnight fast, a single 200-mg oral dose of norfloxacin with water, whole milk, and unflavored yoghurt. Coadministration of milk or yoghurt reduced the extent of norfloxacin absorption and the mean peak concentration in plasma by approximately 50%. Taking of norfloxacin with these liquid dairy products should be avoided.

Entities: Chemical

Mesh：

Substances：
Norfloxacin

Year: 1992 PMID： 1605619 PMCID： PMC188466 DOI： 10.1128/AAC.36.2.489

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

13 in total

1. Interference of dairy products with the absorption of ciprofloxacin.

Authors: P J Neuvonen; K T Kivistö; P Lehto
Journal: Clin Pharmacol Ther Date: 1991-11 Impact factor: 6.875

Review 2. Fluoroquinolone antimicrobial agents.

Authors: D C Hooper; J S Wolfson
Journal: N Engl J Med Date: 1991-02-07 Impact factor: 91.245

3. Ciprofloxacin pharmacokinetics after a standard or high-fat/high-calcium breakfast.

Authors: R W Frost; J D Carlson; A J Dietz; A Heyd; J T Lettieri
Journal: J Clin Pharmacol Date: 1989-10 Impact factor: 3.126

4. Interactions with the absorption of tetracyclines.

Authors: P J Neuvonen
Journal: Drugs Date: 1976 Impact factor: 9.546

5. Effect of ferrous sulfate and multivitamins with zinc on absorption of ciprofloxacin in normal volunteers.

Authors: R E Polk; D P Healy; J Sahai; L Drwal; E Racht
Journal: Antimicrob Agents Chemother Date: 1989-11 Impact factor: 5.191

6. Effects of aluminum and magnesium antacids and ranitidine on the absorption of ciprofloxacin.

Authors: D E Nix; W A Watson; M E Lener; R W Frost; G Krol; H Goldstein; J Lettieri; J J Schentag
Journal: Clin Pharmacol Ther Date: 1989-12 Impact factor: 6.875

Review 7. Clinical pharmacokinetics of ciprofloxacin.

Authors: K Vance-Bryan; D R Guay; J C Rotschafer
Journal: Clin Pharmacokinet Date: 1990-12 Impact factor: 6.447

8. Inhibition of norfloxacin absorption by antacids.

Authors: D E Nix; J H Wilton; B Ronald; L Distlerath; V C Williams; A Norman
Journal: Antimicrob Agents Chemother Date: 1990-03 Impact factor: 5.191

Review 9. Norfloxacin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.

Authors: B Holmes; R N Brogden; D M Richards
Journal: Drugs Date: 1985-12 Impact factor: 9.546

Review 10. Ofloxacin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.

Authors: J P Monk; D M Campoli-Richards
Journal: Drugs Date: 1987-04 Impact factor: 9.546

12 in total

1. Effects of dairy products on the oral bioavailability of moxifloxacin, a novel 8-methoxyfluoroquinolone, in healthy volunteers.

Authors: H Stass; D Kubitza
Journal: Clin Pharmacokinet Date: 2001 Impact factor: 6.447

2. Effects of milk and food on the absorption of enoxacin.

Authors: P Lehto; K T Kivistö
Journal: Br J Clin Pharmacol Date: 1995-02 Impact factor: 4.335

3. Effect of sucralfate on absorption of norfloxacin and ofloxacin.

Authors: P Lehto; K T Kivistö
Journal: Antimicrob Agents Chemother Date: 1994-02 Impact factor: 5.191

4. The effect of milk consumption on the pharmacokinetics of fleroxacin and ciprofloxacin in healthy volunteers.

Authors: J F Hoogkamer; C H Kleinbloesem
Journal: Drugs Date: 1995 Impact factor: 9.546

5. Effect of enteral feeding with ensure on oral bioavailabilities of ofloxacin and ciprofloxacin.

Authors: B A Mueller; D G Brierton; S R Abel; L Bowman
Journal: Antimicrob Agents Chemother Date: 1994-09 Impact factor: 5.191

Review 6. Enoxacin: a reappraisal of its clinical efficacy in the treatment of genitourinary tract infections.

Authors: S S Patel; C M Spencer
Journal: Drugs Date: 1996-01 Impact factor: 9.546

Review 7. Pharmacokinetics and pharmacodynamics of fluoroquinolones.

Authors: J Turnidge
Journal: Drugs Date: 1999 Impact factor: 9.546

Review 8. Older adults with difficulty swallowing oral medicines: a systematic review of the literature.

Authors: Aoife Mc Gillicuddy; Abina M Crean; Laura J Sahm
Journal: Eur J Clin Pharmacol Date: 2015-11-16 Impact factor: 2.953

9. Effect of a fat- and calcium-rich breakfast on pharmacokinetics of fleroxacin administered in single and multiple doses.

Authors: J S Bertino; A N Nafziger; M Wong; L Stragand; C Puleo
Journal: Antimicrob Agents Chemother Date: 1994-03 Impact factor: 5.191

10. The effect of ferrous sulphate on the absorption of norfloxacin, ciprofloxacin and ofloxacin.

Authors: P Lehto; K T Kivistö; P J Neuvonen
Journal: Br J Clin Pharmacol Date: 1994-01 Impact factor: 4.335