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Literature DB >> 16048994

Integron-encoded GES-type extended-spectrum beta-lactamase with increased activity toward aztreonam in Pseudomonas aeruginosa.

Laurent Poirel¹, Laura Brinas, Nicolas Fortineau, Patrice Nordmann.

Abstract

A Pseudomonas aeruginosa strain expresses an extended-spectrum beta-lactamase, GES-9, which differs from GES-1 by a Gly243Ser substitution, is inhibited by clavulanic acid and imipenem, and hydrolyzes aztreonam. The bla(GES-9) gene was located inside a class 1 integron structure containing two copies of a novel insertion sequence belonging to the IS1111 family.

Entities: Chemical Species

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Year: 2005 PMID： 16048994 PMCID： PMC1196234 DOI： 10.1128/AAC.49.8.3593-3597.2005

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

28 in total

1. Biochemical sequence analyses of GES-1, a novel class A extended-spectrum beta-lactamase, and the class 1 integron In52 from Klebsiella pneumoniae.

Authors: L Poirel; I Le Thomas; T Naas; A Karim; P Nordmann
Journal: Antimicrob Agents Chemother Date: 2000-03 Impact factor: 5.191

2. An integron-associated beta-lactamase (IBC-2) from Pseudomonas aeruginosa is a variant of the extended-spectrum beta-lactamase IBC-1.

Authors: A Mavroidi; E Tzelepi; A Tsakris; V Miriagou; D Sofianou; L S Tzouvelekis
Journal: J Antimicrob Chemother Date: 2001-11 Impact factor: 5.790

3. Functional Tn5393-like transposon in the R plasmid pRAS2 from the fish pathogen Aeromonas salmonicida subspecies salmonicida isolated in Norway.

Authors: T M L'Abée-Lund; H Sørum
Journal: Appl Environ Microbiol Date: 2000-12 Impact factor: 4.792

4. Nomenclature of GES-type extended-spectrum beta-lactamases.

Authors: Sang Hee Lee; Seok Hoon Jeong
Journal: Antimicrob Agents Chemother Date: 2005-05 Impact factor: 5.191

5. Nosocomial spread of the integron-located veb-1-like cassette encoding an extended-pectrum beta-lactamase in Pseudomonas aeruginosa in Thailand.

Authors: Delphine Girlich; Thierry Naas; Amornrut Leelaporn; Laurent Poirel; Michael Fennewald; Patrice Nordmann
Journal: Clin Infect Dis Date: 2002-01-23 Impact factor: 9.079

6. Class 1 integrons mediate antibiotic resistance in the fish pathogen Aeromonas salmonicida worldwide.

Authors: T M L'Abée-Lund; H Sørum
Journal: Microb Drug Resist Date: 2001 Impact factor: 3.431

7. The inverted repeats of IS1384, a newly described insertion sequence from Pseudomonas putida strain H, represent the specific target for integration of IS1383.

Authors: C Müller; U Lauf; H Hermann
Journal: Mol Genet Genomics Date: 2001-08 Impact factor: 3.291

8. GES-2, a class A beta-lactamase from Pseudomonas aeruginosa with increased hydrolysis of imipenem.

Authors: L Poirel; G F Weldhagen; T Naas; C De Champs; M G Dove; P Nordmann
Journal: Antimicrob Agents Chemother Date: 2001-09 Impact factor: 5.191

9. A nosocomial outbreak of Pseudomonas aeruginosa isolates expressing the extended-spectrum beta-lactamase GES-2 in South Africa.

Authors: Laurent Poirel; Gerhard F Weldhagen; Christophe De Champs; Patrice Nordmann
Journal: J Antimicrob Chemother Date: 2002-03 Impact factor: 5.790

10. Molecular characterization of a novel class 1 integron containing bla(GES-1) and a fused product of aac3-Ib/aac6'-Ib' gene cassettes in Pseudomonas aeruginosa.

Authors: Véronique Dubois; Laurent Poirel; Caroline Marie; Corinne Arpin; Patrice Nordmann; Claudine Quentin
Journal: Antimicrob Agents Chemother Date: 2002-03 Impact factor: 5.191

25 in total

Review 1. A Structure-Based Classification of Class A β-Lactamases, a Broadly Diverse Family of Enzymes.

Authors: Alain Philippon; Patrick Slama; Paul Dény; Roger Labia
Journal: Clin Microbiol Rev Date: 2016-01 Impact factor: 26.132

2. Pyrosequencing as a rapid tool for identification of GES-type extended-spectrum beta-lactamases.

Authors: Laurent Poirel; Thierry Naas; Patrice Nordmann
Journal: J Clin Microbiol Date: 2006-08 Impact factor: 5.948

Review 3. Carbapenemases: the versatile beta-lactamases.

Authors: Anne Marie Queenan; Karen Bush
Journal: Clin Microbiol Rev Date: 2007-07 Impact factor: 26.132

4. GES-13, a beta-lactamase variant possessing Lys-104 and Asn-170 in Pseudomonas aeruginosa.

Authors: S D Kotsakis; C C Papagiannitsis; E Tzelepi; N J Legakis; V Miriagou; L S Tzouvelekis
Journal: Antimicrob Agents Chemother Date: 2010-01-11 Impact factor: 5.191

5. In vitro prediction of the evolution of GES-1 β-lactamase hydrolytic activity.

Authors: Séverine Bontron; Laurent Poirel; Patrice Nordmann
Journal: Antimicrob Agents Chemother Date: 2015-01-05 Impact factor: 5.191

6. Nationwide investigation of extended-spectrum beta-lactamases, metallo-beta-lactamases, and extended-spectrum oxacillinases produced by ceftazidime-resistant Pseudomonas aeruginosa strains in France.

Authors: Didier Hocquet; Patrick Plésiat; Barbara Dehecq; Pierre Mariotte; Daniel Talon; Xavier Bertrand
Journal: Antimicrob Agents Chemother Date: 2010-06-14 Impact factor: 5.191