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Literature DB >> 19451292

GES-11, a novel integron-associated GES variant in Acinetobacter baumannii.

Carole Moubareck¹, Sylvie Brémont, Marie-Christine Conroy, Patrice Courvalin, Thierry Lambert.

Abstract

New extended-spectrum beta-lactamase GES-11 was detected in Acinetobacter baumannii BM4674. The enzyme conferred resistance to beta-lactams, including aztreonam, and reduced susceptibility to carbapenems. The structural gene was part of a class 1 integron borne by self-transferable plasmid pIP847. GES-type beta-lactamases have not been reported previously in A. baumannii.

Entities: Chemical Species

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Year: 2009 PMID： 19451292 PMCID： PMC2715621 DOI： 10.1128/AAC.00072-09

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

20 in total

1. Biochemical sequence analyses of GES-1, a novel class A extended-spectrum beta-lactamase, and the class 1 integron In52 from Klebsiella pneumoniae.

Authors: L Poirel; I Le Thomas; T Naas; A Karim; P Nordmann
Journal: Antimicrob Agents Chemother Date: 2000-03 Impact factor: 5.191

2. Genetic environment of quinolone resistance gene qnrB2 in a complex sul1-type integron in the newly described Salmonella enterica serovar Keurmassar.

Authors: Fabien Garnier; Nabil Raked; Amy Gassama; François Denis; Marie-Cécile Ploy
Journal: Antimicrob Agents Chemother Date: 2006-09 Impact factor: 5.191

Review 3. Modes and modulations of antibiotic resistance gene expression.

Authors: Florence Depardieu; Isabelle Podglajen; Roland Leclercq; Ekkehard Collatz; Patrice Courvalin
Journal: Clin Microbiol Rev Date: 2007-01 Impact factor: 26.132

Review 4. Carbapenemases: the versatile beta-lactamases.

Authors: Anne Marie Queenan; Karen Bush
Journal: Clin Microbiol Rev Date: 2007-07 Impact factor: 26.132

Review 5. Carbapenem resistance in Acinetobacter baumannii: mechanisms and epidemiology.

Authors: L Poirel; P Nordmann
Journal: Clin Microbiol Infect Date: 2006-09 Impact factor: 8.067

6. Molecular characterization of a new class 3 integron in Klebsiella pneumoniae.

Authors: Mário Correia; Filipa Boavida; Filipa Grosso; M J Salgado; L M Lito; J Melo Cristino; Sónia Mendo; Aida Duarte
Journal: Antimicrob Agents Chemother Date: 2003-09 Impact factor: 5.191

7. Novel GES/IBC extended-spectrum beta-lactamase variants with carbapenemase activity in clinical enterobacteria.

Authors: Sofia Vourli; Panagiota Giakkoupi; Vivi Miriagou; Eva Tzelepi; Alkiviadis C Vatopoulos; Leonidas S Tzouvelekis
Journal: FEMS Microbiol Lett Date: 2004-05-15 Impact factor: 2.742

Review 8. Acinetobacter baumannii: a universal threat to public health?

Authors: Helen Giamarellou; Anastasia Antoniadou; Kyriaki Kanellakopoulou
Journal: Int J Antimicrob Agents Date: 2008-06-20 Impact factor: 5.283

Review 9. Acinetobacter baumannii: epidemiology, antimicrobial resistance, and treatment options.

Authors: Lisa L Maragakis; Trish M Perl
Journal: Clin Infect Dis Date: 2008-04-15 Impact factor: 9.079

10. Contribution of extended-spectrum AmpC (ESAC) beta-lactamases to carbapenem resistance in Escherichia coli.

Authors: Hedi Mammeri; Patrice Nordmann; Amira Berkani; François Eb
Journal: FEMS Microbiol Lett Date: 2008-03-27 Impact factor: 2.742

42 in total

1. GES-13, a beta-lactamase variant possessing Lys-104 and Asn-170 in Pseudomonas aeruginosa.

Authors: S D Kotsakis; C C Papagiannitsis; E Tzelepi; N J Legakis; V Miriagou; L S Tzouvelekis
Journal: Antimicrob Agents Chemother Date: 2010-01-11 Impact factor: 5.191

2. Kinetic characterization of GES-22 β-lactamase harboring the M169L clinical mutation.

Authors: Aysegul Saral; David A Leonard; Azer Ozad Duzgun; Aysegul Copur Cicek; Cynthia M June; Cemal Sandalli
Journal: J Antibiot (Tokyo) Date: 2016-05-11 Impact factor: 2.649

3. Clinical carbapenem-resistant Acinetobacter baylyi strain coharboring blaSIM-1 and blaOXA-23 from China.

Authors: Zhihui Zhou; Xiaoxing Du; Li Wang; Qing Yang; Yiqi Fu; Yunsong Yu
Journal: Antimicrob Agents Chemother Date: 2011-08-29 Impact factor: 5.191

4. Evaluation of clonality and carbapenem resistance mechanisms among Acinetobacter baumannii-Acinetobacter calcoaceticus complex and Enterobacteriaceae isolates collected in European and Mediterranean countries and detection of two novel β-lactamases, GES-22 and VIM-35.

Authors: Mariana Castanheira; Sarah E Costello; Leah N Woosley; Lalitagauri M Deshpande; Todd A Davies; Ronald N Jones
Journal: Antimicrob Agents Chemother Date: 2014-09-29 Impact factor: 5.191