| Literature DB >> 16038551 |
Amooru G Damu1, Ping-Chung Kuo, Li-Shian Shi, Chia-Ying Li, Chang-Sheng Kuoh, Pei-Lin Wu, Tian-Shung Wu.
Abstract
In addition to six known phenanthroindolizidine alkaloids, eight new alkaloids, namely, ficuseptines B-D (1-3), 10R,13aR-tylophorine N-oxide (4), 10R,13aR-tylocrebrine N-oxide (5), 10S,13aR-tylocrebrine N-oxide (6), 10S,13aR-isotylocrebrine N-oxide (7), and 10S,13aS-isotylocrebrine N-oxide (8), were isolated from a methanol extract of the stems of Ficus septica. The structures of the new compounds were elucidated by means of spectroscopic data interpretation. Cytotoxicity of some of these alkaloids was assessed in vitro using the HONE-1 and NUGC cell lines.Entities:
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Year: 2005 PMID： 16038551 DOI： 10.1021/np050095o
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050