| Literature DB >> 16034480 |
D Hebenstreit1, J Horejs-Hoeck, A Duschl.
Abstract
The Janus kinase-signal transducer and activator of transcription (Jak-STAT) pathway is essential for the signal transduction of many cytokines. Dysregulation of Jak-STAT signaling is associated with various human diseases. Recent studies have helped to shed some light on regulatory mechanisms that modify quantity and quality of the signaling response. Here, we summarize our current knowledge on Jak-STAT signaling. 2005 Prous Science. All rights reservedEntities:
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Year: 2005 PMID: 16034480 DOI: 10.1358/dnp.2005.18.4.908658
Source DB: PubMed Journal: Drug News Perspect ISSN: 0214-0934