Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 JAK-STAT pathway in carcinogenesis: is it relevant to cholangiocarcinoma progression?

Literature DB >> 18161917

JAK-STAT pathway in carcinogenesis: is it relevant to cholangiocarcinoma progression?

Olga V Smirnova¹, Tatiana Yu Ostroukhova, Roman L Bogorad.

Abstract

The features of JAK-STAT signaling in liver cells are discussed in the current review. The role of this signaling cascade in carcinogenesis is accentuated. The possible involvement of this pathway and alteration of its elements are compared for normal cholangiocytes, cholangiocarcinoma predisposition and development. Prolactin and interleukin-6 are described in detail as the best studied examples. In addition, the non-classical nuclear translocation of cytokine receptors is discussed in terms of its possible implication to cholangiocarcinoma development.

Entities: Disease Gene

Mesh：

Substances：

Year: 2007 PMID： 18161917 PMCID： PMC4611286 DOI： 10.3748/wjg.v13.i48.6478

Source DB: PubMed Journal: World J Gastroenterol ISSN： 1007-9327 Impact factor: 5.742

183 in total

1. Characterization of human mucin gene MUC4 promoter: importance of growth factors and proinflammatory cytokines for its regulation in pancreatic cancer cells.

Authors: M Perrais; P Pigny; M P Ducourouble; D Petitprez; N Porchet; J P Aubert; I Van Seuningen
Journal: J Biol Chem Date: 2001-06-19 Impact factor: 5.157

Review 2. SFK-STAT pathway: an alternative and important way to malignancies.

Authors: Fumihiko Hayakawa; Tomoki Naoe
Journal: Ann N Y Acad Sci Date: 2006-11 Impact factor: 5.691

3. Cross-talk between Stat5b and estrogen receptor-alpha and -beta in mammary epithelial cells.

Authors: L Björnström; E Kilic; M Norman; M G Parker; M Sjöberg
Journal: J Mol Endocrinol Date: 2001-08 Impact factor: 5.098

4. Prolactin modulates phosphorylation, signaling and trafficking of epidermal growth factor receptor in human T47D breast cancer cells.

Authors: Y Huang; X Li; J Jiang; S J Frank
Journal: Oncogene Date: 2006-06-19 Impact factor: 9.867

5. Autocrine-mediated activation of STAT3 correlates with cell proliferation in breast carcinoma lines.

Authors: Li Li; Peter E Shaw
Journal: J Biol Chem Date: 2002-02-21 Impact factor: 5.157

6. Estradiol represses prolactin-induced expression of Na+/taurocholate cotransporting polypeptide in liver cells through estrogen receptor-alpha and signal transducers and activators of transcription 5a.

Authors: Jingsong Cao; Marcie Wood; Yong Liu; Tim Hoffman; Jim Hyde; Ok-Kyong Park-Sarge; Mary Vore
Journal: Endocrinology Date: 2003-12-18 Impact factor: 4.736

7. Cell proliferation and oncogene expression after bile duct ligation in the rat: evidence of a specific growth effect on bile duct cells.

Authors: L Polimeno; A Azzarone; Q H Zeng; C Panella; V Subbotin; B Carr; B Bouzahzah; A Francavilla; T E Starzl
Journal: Hepatology Date: 1995-04 Impact factor: 17.425

8. Nuclear translocation and retention of growth hormone.

Authors: Hichem C Mertani; Mireille Raccurt; Aude Abbate; Jenny Kindblom; Jan Törnell; Nils Billestrup; Yves Usson; Gérard Morel; Peter E Lobie
Journal: Endocrinology Date: 2003-07 Impact factor: 4.736

9. Long isoform of prolactin receptor predominates in rat intrahepatic bile ducts and further increases under obstructive cholestasis.

Authors: R L Bogorad; T Y Ostroukhova; A N Orlova; P M Rubtsov; O V Smirnova
Journal: J Endocrinol Date: 2006-02 Impact factor: 4.286

10. Prostate cancer cell proliferation is influenced by leptin.

Authors: Ponnandai Somasundar; Krista A Frankenberry; Heath Skinner; Giridhar Vedula; David W McFadden; Dale Riggs; Barbara Jackson; Reyna Vangilder; Stanley M Hileman; Linda C Vona-Davis
Journal: J Surg Res Date: 2004-05-01 Impact factor: 2.192

12 in total

1. The tetrad BMI, leptin, leptin/adiponectin (L/A) ratio and CA 15-3 are reliable biomarkers of breast cancer.

Authors: Jonnathan G Santillán-Benítez; Hugo Mendieta-Zerón; Leobardo M Gómez-Oliván; Juan J Torres-Juárez; Juan M González-Bañales; Lorena V Hernández-Peña; Angel Ordóñez-Quiroz
Journal: J Clin Lab Anal Date: 2013-01-04 Impact factor: 2.352

2. Significance and relationship between Cripto-1 and p-STAT3 expression in gastric cancer and precancerous lesions.

Authors: Jian-Guo Zhang; Jing Zhao; Yan Xin
Journal: World J Gastroenterol Date: 2010-02-07 Impact factor: 5.742

3. Aberrantly methylated-differentially expressed genes and related pathways in cholangiocarcinoma.

Authors: Guan Lin; Zhang Xinhe; Tian Haoyu; Li Yiling
Journal: Medicine (Baltimore) Date: 2022-06-24 Impact factor: 1.817

Review 4. Organogenesis and tumorigenesis: insight from the JAK/STAT pathway in the Drosophila eye.

Authors: Ying-Hsuan Wang; Min-Lang Huang
Journal: Dev Dyn Date: 2010-10 Impact factor: 3.780

5. Mechanisms of resistance to sorafenib and the corresponding strategies in hepatocellular carcinoma.

Authors: Bo Zhai; Xue-Ying Sun
Journal: World J Hepatol Date: 2013-07-27

6. Essential role of JAK/STAT pathway in the induction of cell cycle arrest in macrophages infected with periodontopathic bacterium Aggregatibacter actinomycetemcomitans.

Authors: Toshinori Okinaga; Wataru Ariyoshi; Sumio Akifusa; Tatsuji Nishihara
Journal: Med Microbiol Immunol Date: 2012-12-25 Impact factor: 3.402

7. Identification of tyrosine-phosphorylated proteins associated with metastasis and functional analysis of FER in human hepatocellular carcinoma cells.

Authors: Haiyu Li; Zhenggang Ren; Xiaonan Kang; Lan Zhang; Xuefei Li; Yan Wang; Tongchun Xue; Yuefang Shen; Yinkun Liu
Journal: BMC Cancer Date: 2009-10-16 Impact factor: 4.430

8. Viral hepatitis-associated intrahepatic cholangiocarcinoma shares common disease processes with hepatocellular carcinoma.

Authors: C H Lee; C J Chang; Y J Lin; C N Yeh; M F Chen; S Y Hsieh
Journal: Br J Cancer Date: 2009-05-12 Impact factor: 7.640

9. Apoptosis Induced by Tanshinone IIA and Cryptotanshinone Is Mediated by Distinct JAK/STAT3/5 and SHP1/2 Signaling in Chronic Myeloid Leukemia K562 Cells.

Authors: Ji Hoon Jung; Tae-Rin Kwon; Soo-Jin Jeong; Eun-Ok Kim; Eun Jung Sohn; Miyong Yun; Sung-Hoon Kim
Journal: Evid Based Complement Alternat Med Date: 2013-06-26 Impact factor: 2.629

10. Detection of deregulated modules using deregulatory linked path.

Authors: Yuxuan Hu; Lin Gao; Kai Shi; David K Y Chiu
Journal: PLoS One Date: 2013-07-24 Impact factor: 3.240