OBJECTIVES: We evaluated the axial location of plaque ruptures in native coronary arteries. BACKGROUND: It is clinically important to understand the potential sites of plaque rupture. METHODS: We performed three-vessel intravascular ultrasound (IVUS) examination in 392 patients; 231 had acute coronary syndrome (ACS) and 161 had stable angina pectoris (SAP). The IVUS detected plaque ruptures in 206 patients: 158 ACS patients and 48 SAP patients. The distance between each coronary plaque rupture segment and the respective coronary ostium was measured with motorized IVUS transducer pullback in all three coronary arteries. RESULTS: There were a total of 273 plaque ruptures in these 206 patients; 143 in the left anterior descending artery (LAD), 40 in the left circumflex artery (LCX), and 90 in the right coronary artery (RCA). There were 67 plaque ruptures in SAP patients and 206 in ACS patients; there were 197 culprit/target lesion plaque ruptures and 76 non-culprit/non-target lesion plaque ruptures. The LAD plaque ruptures were predominantly located between 10 and 40 mm from the LAD ostium (83%, 119 of 143). The LCX plaque ruptures were evenly distributed in the entire LCX tree. Most RCA plaque ruptures were located in segments between 10 and 40 mm (48%, 43 of 90) and in segments >70 mm from the ostium (32%, 29 of 90). CONCLUSIONS: Three-vessel IVUS imaging showed that plaque ruptures occurred mainly in proximal segments of the LAD (83% of LAD plaque rupture), the proximal and distal segments of the RCA (48% and 32% of RCA plaque ruptures, respectively), and the entire LCX.
OBJECTIVES: We evaluated the axial location of plaque ruptures in native coronary arteries. BACKGROUND: It is clinically important to understand the potential sites of plaque rupture. METHODS: We performed three-vessel intravascular ultrasound (IVUS) examination in 392 patients; 231 had acute coronary syndrome (ACS) and 161 had stable angina pectoris (SAP). The IVUS detected plaque ruptures in 206 patients: 158 ACS patients and 48 SAP patients. The distance between each coronary plaque rupture segment and the respective coronary ostium was measured with motorized IVUS transducer pullback in all three coronary arteries. RESULTS: There were a total of 273 plaque ruptures in these 206 patients; 143 in the left anterior descending artery (LAD), 40 in the left circumflex artery (LCX), and 90 in the right coronary artery (RCA). There were 67 plaque ruptures in SAP patients and 206 in ACS patients; there were 197 culprit/target lesion plaque ruptures and 76 non-culprit/non-target lesion plaque ruptures. The LAD plaque ruptures were predominantly located between 10 and 40 mm from the LAD ostium (83%, 119 of 143). The LCX plaque ruptures were evenly distributed in the entire LCX tree. Most RCA plaque ruptures were located in segments between 10 and 40 mm (48%, 43 of 90) and in segments >70 mm from the ostium (32%, 29 of 90). CONCLUSIONS: Three-vessel IVUS imaging showed that plaque ruptures occurred mainly in proximal segments of the LAD (83% of LAD plaque rupture), the proximal and distal segments of the RCA (48% and 32% of RCA plaque ruptures, respectively), and the entire LCX.
Authors: F Cademartiri; L La Grutta; A Palumbo; E Maffei; A Aldrovandi; R Malagò; F Alberghina; F Pugliese; G Runza; M Belgrano; M Midiri; M A Cova; G P Krestin Journal: Radiol Med Date: 2007-07-24 Impact factor: 3.469
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Authors: Andreas König; Øyvind Bleie; Johannes Rieber; Philip Jung; Thomas M Schiele; Hae-Young Sohn; Marcus Leibig; Uwe Siebert; Volker Klauss Journal: Clin Res Cardiol Date: 2009-09-19 Impact factor: 5.460
Authors: F Cademartiri; L La Grutta; R Malagò; F Alberghina; A Palumbo; M Belgrano; E Maffei; A Aldrovandi; F Pugliese; G Runza; A Weustink; W Bob Meeijboom; N R Mollet; M Midiri Journal: Radiol Med Date: 2009-04-15 Impact factor: 3.469
Authors: Michiel Schaap; Coert T Metz; Theo van Walsum; Alina G van der Giessen; Annick C Weustink; Nico R Mollet; Christian Bauer; Hrvoje Bogunović; Carlos Castro; Xiang Deng; Engin Dikici; Thomas O'Donnell; Michel Frenay; Ola Friman; Marcela Hernández Hoyos; Pieter H Kitslaar; Karl Krissian; Caroline Kühnel; Miguel A Luengo-Oroz; Maciej Orkisz; Orjan Smedby; Martin Styner; Andrzej Szymczak; Hüseyin Tek; Chunliang Wang; Simon K Warfield; Sebastian Zambal; Yong Zhang; Gabriel P Krestin; Wiro J Niessen Journal: Med Image Anal Date: 2009-06-30 Impact factor: 8.545