Literature DB >> 18188509

ST deviation pattern in acute myocardial infarction is not related to lesion location.

David Rott1, Penko Greganski, Johannes Nowatzky, A Teddy Weiss, Tova Chajek-Shaul, David Leibowitz.   

Abstract

BACKGROUND: In ST-elevation MI (STEMI) the culprit artery is usually occluded, whereas non-STEMI (NSTEMI) it is usually patent. The location of the ruptured plaque may influence MI type. We examine whether the distance from the coronary ostium to the culprit lesion is different in STEMI as compared to NSTEMI.
METHODS: We selected patients who presented with an acute MI and underwent coronary angiography during hospitalization. The analysis included 754 patients of whom 514 had STEMI and 240 had NSTEMI. The distance from the coronary ostium to the site of thrombosis was measured.
RESULTS: For both STEMI and NSTEMI patients the first 60 mm of the coronary artery contained 75% of the culprit lesions. There were no significant differences in median distances from the vessel ostium to the site of thrombosis as well.
CONCLUSIONS: The distance from coronary ostium to culprit lesion is similar in STEMI and NSTEMI. Culprit lesion location does not appear to influence the development of STEMI as opposed to NSTEMI.

Entities:  

Mesh:

Year:  2008        PMID: 18188509     DOI: 10.1007/s11239-008-0193-2

Source DB:  PubMed          Journal:  J Thromb Thrombolysis        ISSN: 0929-5305            Impact factor:   2.300


  12 in total

Review 1.  Current concepts of the pathogenesis of the acute coronary syndromes.

Authors:  P Libby
Journal:  Circulation       Date:  2001-07-17       Impact factor: 29.690

2.  The site of plaque rupture in native coronary arteries: a three-vessel intravascular ultrasound analysis.

Authors:  Myeong-Ki Hong; Gary S Mintz; Cheol Whan Lee; Bong-Ki Lee; Tae-Hyun Yang; Young-Hak Kim; Jong-Min Song; Ki-Hoon Han; Duk-Hyun Kang; Sang-Sig Cheong; Jae-Kwan Song; Jae-Joong Kim; Seong-Wook Park; Seung-Jung Park
Journal:  J Am Coll Cardiol       Date:  2005-07-19       Impact factor: 24.094

Review 3.  Stability and instability: two faces of coronary atherosclerosis. The Paul Dudley White Lecture 1995.

Authors:  M J Davies
Journal:  Circulation       Date:  1996-10-15       Impact factor: 29.690

4.  ST-deviation patterns in recurrent myocardial infarctions.

Authors:  David Rott; A Teddy Weiss; Tova Chajek-Shaul; David Leibowitz
Journal:  Am J Cardiol       Date:  2006-04-27       Impact factor: 2.778

5.  Normal flow (TIMI-3) before mechanical reperfusion therapy is an independent determinant of survival in acute myocardial infarction: analysis from the primary angioplasty in myocardial infarction trials.

Authors:  G W Stone; D Cox; E Garcia; B R Brodie; M C Morice; J Griffin; L Mattos; A J Lansky; W W O'Neill; C L Grines
Journal:  Circulation       Date:  2001-08-07       Impact factor: 29.690

Review 6.  Pathology of the unstable plaque.

Authors:  Renu Virmani; Allen P Burke; Andrew Farb; Frank D Kolodgie
Journal:  Prog Cardiovasc Dis       Date:  2002 Mar-Apr       Impact factor: 8.194

7.  Coronary artery spatial distribution of acute myocardial infarction occlusions.

Authors:  John C Wang; Sharon-Lise T Normand; Laura Mauri; Richard E Kuntz
Journal:  Circulation       Date:  2004-07-12       Impact factor: 29.690

8.  ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction; A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Revise the 1999 Guidelines for the Management of patients with acute myocardial infarction).

Authors:  Elliott M. Antman; Daniel T. Anbe; Paul Wayne Armstrong; Eric R. Bates; Lee A. Green; Mary Hand; Judith S. Hochman; Harlan M. Krumholz; Frederick G. Kushner; Gervasio A. Lamas; Charles J. Mullany; Joseph P. Ornato; David L. Pearle; Michael A. Sloan; Sidney C. Smith; Joseph S. Alpert; Jeffrey L. Anderson; David P. Faxon; Valentin Fuster; Raymond J. Gibbons; Gabriel Gregoratos; Jonathan L. Halperin; Loren F. Hiratzka; Sharon Ann Hunt; Alice K. Jacobs; Joseph P. Ornato
Journal:  J Am Coll Cardiol       Date:  2004-08-04       Impact factor: 24.094

9.  Distance from the coronary ostium to the culprit lesion in acute ST-elevation myocardial infarction and its implications regarding the potential prevention of proximal plaque rupture.

Authors:  C Michael Gibson; Ajay J Kirtane; Sabina A Murphy; Juhana Karha; Christopher P Cannon; Robert P Giugliano; Mathew T Roe; Robert A Harrington; E Magnus Ohman; Elliott M Antman
Journal:  J Thromb Thrombolysis       Date:  2003-06       Impact factor: 2.300

10.  ACC/AHA 2007 guidelines for the management of patients with unstable angina/non-ST-Elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines for the Management of Patients With Unstable Angina/Non-ST-Elevation Myocardial Infarction) developed in collaboration with the American College of Emergency Physicians, the Society for Cardiovascular Angiography and Interventions, and the Society of Thoracic Surgeons endorsed by the American Association of Cardiovascular and Pulmonary Rehabilitation and the Society for Academic Emergency Medicine.

Authors:  Jeffrey L Anderson; Cynthia D Adams; Elliott M Antman; Charles R Bridges; Robert M Califf; Donald E Casey; William E Chavey; Francis M Fesmire; Judith S Hochman; Thomas N Levin; A Michael Lincoff; Eric D Peterson; Pierre Theroux; Nanette Kass Wenger; R Scott Wright; Sidney C Smith; Alice K Jacobs; Cynthia D Adams; Jeffrey L Anderson; Elliott M Antman; Jonathan L Halperin; Sharon A Hunt; Harlan M Krumholz; Frederick G Kushner; Bruce W Lytle; Rick Nishimura; Joseph P Ornato; Richard L Page; Barbara Riegel
Journal:  J Am Coll Cardiol       Date:  2007-08-14       Impact factor: 24.094

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