Literature DB >> 15995674

Molecular farming for new drugs and vaccines. Current perspectives on the production of pharmaceuticals in transgenic plants.

Julian K-C Ma1, Eugenia Barros, Ralph Bock, Paul Christou, Philip J Dale, Philip J Dix, Rainer Fischer, Judith Irwin, Richard Mahoney, Mario Pezzotti, Stefan Schillberg, Penny Sparrow, Eva Stoger, Richard M Twyman.   

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Year:  2005        PMID： 15995674      PMCID： PMC1369121          DOI： 10.1038/sj.embor.7400470

Source DB:  PubMed          Journal:  EMBO Rep        ISSN： 1469-221X            Impact factor:   8.807


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  25 in total

1.  Linear transgene constructs lacking vector backbone sequences generate low-copy-number transgenic plants with simple integration patterns.

Authors:  X Fu; L T Duc; S Fontana; B B Bong; P Tinjuangjun; D Sudhakar; R M Twyman; P Christou; A Kohli
Journal:  Transgenic Res       Date:  2000-02       Impact factor: 2.788

Review 2.  Transgenic plastids in basic research and plant biotechnology.

Authors:  R Bock
Journal:  J Mol Biol       Date:  2001-09-21       Impact factor: 5.469

Review 3.  Molecular strategies for gene containment in transgenic crops.

Authors:  Henry Daniell
Journal:  Nat Biotechnol       Date:  2002-06       Impact factor: 54.908

Review 4.  Molecular farming in plants: host systems and expression technology.

Authors:  Richard M Twyman; Eva Stoger; Stefan Schillberg; Paul Christou; Rainer Fischer
Journal:  Trends Biotechnol       Date:  2003-12       Impact factor: 19.536

Review 5.  The production of recombinant pharmaceutical proteins in plants.

Authors:  Julian K-C Ma; Pascal M W Drake; Paul Christou
Journal:  Nat Rev Genet       Date:  2003-10       Impact factor: 53.242

Review 6.  Inhibiting sexual transmission of HIV-1 infection.

Authors:  Robin J Shattock; John P Moore
Journal:  Nat Rev Microbiol       Date:  2003-10       Impact factor: 60.633

7.  Expression and inheritance of multiple transgenes in rice plants.

Authors:  L Chen; P Marmey; N J Taylor; J P Brizard; C Espinoza; P D'Cruz; H Huet; S Zhang; A de Kochko; R N Beachy; C M Fauquet
Journal:  Nat Biotechnol       Date:  1998-11       Impact factor: 54.908

8.  Expression in plants and immunogenicity of plant virus-based experimental rabies vaccine.

Authors:  V Yusibov; D C Hooper; S V Spitsin; N Fleysh; R B Kean; T Mikheeva; D Deka; A Karasev; S Cox; J Randall; H Koprowski
Journal:  Vaccine       Date:  2002-08-19       Impact factor: 3.641

9.  Generation of Arabidopsis thaliana plants with complex N-glycans lacking beta1,2-linked xylose and core alpha1,3-linked fucose.

Authors:  R Strasser; F Altmann; L Mach; J Glössl; H Steinkellner
Journal:  FEBS Lett       Date:  2004-03-12       Impact factor: 4.124

10.  Ethanol vapor is an efficient inducer of the alc gene expression system in model and crop plant species.

Authors:  Justin P Sweetman; Chengcai Chu; Nan Qu; Andrew J Greenland; Uwe Sonnewald; Ian Jepson
Journal:  Plant Physiol       Date:  2002-07       Impact factor: 8.340
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  65 in total

1.  Inducible gene expression from the plastid genome by a synthetic riboswitch.

Authors:  Andreas Verhounig; Daniel Karcher; Ralph Bock
Journal:  Proc Natl Acad Sci U S A       Date:  2010-03-22       Impact factor: 11.205

2.  Aberrant localization and underglycosylation of highly accumulating single-chain Fv-Fc antibodies in transgenic Arabidopsis seeds.

Authors:  Bart Van Droogenbroeck; Jingyuan Cao; Johannes Stadlmann; Friedrich Altmann; Sarah Colanesi; Stefan Hillmer; David G Robinson; Els Van Lerberge; Nancy Terryn; Marc Van Montagu; Mifang Liang; Ann Depicker; Geert De Jaeger
Journal:  Proc Natl Acad Sci U S A       Date:  2007-01-16       Impact factor: 11.205

3.  Plastid Transformation in Tomato: A Vegetable Crop and Model Species.

Authors:  Stephanie Ruf; Ralph Bock
Journal:  Methods Mol Biol       Date:  2021

Review 4.  A history of plant biotechnology: from the Cell Theory of Schleiden and Schwann to biotech crops.

Authors:  Indra K Vasil
Journal:  Plant Cell Rep       Date:  2008-07-09       Impact factor: 4.570

5.  Dynamics of global disclosure through patent and journal publications for biopharmaceutical products.

Authors:  Harry Thangaraj; Craig J van Dolleweerd; Edward G McGowan; Julian K-C Ma
Journal:  Nat Biotechnol       Date:  2009-07       Impact factor: 54.908

6.  Plastid transformation in eggplant (Solanum melongena L.).

Authors:  A K Singh; S S Verma; K C Bansal
Journal:  Transgenic Res       Date:  2009-06-28       Impact factor: 2.788

7.  Production of a de-novo designed antimicrobial peptide in Nicotiana benthamiana.

Authors:  Benjamin Zeitler; Antonie Bernhard; Helge Meyer; Michael Sattler; Hans-Ulrich Koop; Christian Lindermayr
Journal:  Plant Mol Biol       Date:  2012-12-16       Impact factor: 4.076

8.  Selection of Shine-Dalgarno sequences in plastids.

Authors:  Oliver Drechsel; Ralph Bock
Journal:  Nucleic Acids Res       Date:  2010-10-21       Impact factor: 16.971

9.  Antibody expressing pea seeds as fodder for prevention of gastrointestinal parasitic infections in chickens.

Authors:  Jana Zimmermann; Isolde Saalbach; Doreen Jahn; Martin Giersberg; Sigrun Haehnel; Julia Wedel; Jeanette Macek; Karen Zoufal; Gerhard Glünder; Dieter Falkenburg; Sergey M Kipriyanov
Journal:  BMC Biotechnol       Date:  2009-09-11       Impact factor: 2.563

Review 10.  Plant-based strategies aimed at expressing HIV antigens and neutralizing antibodies at high levels. Nef as a case study.

Authors:  Carla Marusic; Alessandro Vitale; Emanuela Pedrazzini; Marcello Donini; Lorenzo Frigerio; Ralph Bock; Philip J Dix; Matthew S McCabe; Michele Bellucci; Eugenio Benvenuto
Journal:  Transgenic Res       Date:  2009-01-25       Impact factor: 2.788
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