Literature DB >> 15974933

Allosteric modulation of dopamine receptors.

John A Schetz1.   

Abstract

Allosteric modulators allow for the fine-tuning of receptor responses to endogenous neurotransmitters and exogenous therapeutic agents. Different types of allosteric modulation of dopamine receptors are discussed as well as the significance of such modulation in the control of normal biological processes and in the treatment of disease.

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Year:  2005        PMID： 15974933     DOI： 10.2174/1389557054023260

Source DB:  PubMed          Journal:  Mini Rev Med Chem        ISSN： 1389-5575            Impact factor:   3.862


  9 in total

Review 1.  Modulation of GPCRs by monovalent cations and anions.

Authors:  Andrea Strasser; Hans-Joachim Wittmann; Erich H Schneider; Roland Seifert
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2014-11-30       Impact factor: 3.000

2.  Allosteric modulators: an emerging concept in drug discovery.

Authors:  Ahmed F Abdel-Magid
Journal:  ACS Med Chem Lett       Date:  2015-01-08       Impact factor: 4.345

3.  The tetrahydroisoquinoline derivative SB269,652 is an allosteric antagonist at dopamine D3 and D2 receptors.

Authors:  Elena Silvano; Mark J Millan; Clotilde Mannoury la Cour; Yang Han; Lihua Duan; Suzy A Griffin; Robert R Luedtke; Gabriella Aloisi; Mario Rossi; Francesca Zazzeroni; Jonathan A Javitch; Roberto Maggio
Journal:  Mol Pharmacol       Date:  2010-08-11       Impact factor: 4.436

4.  Sodium binding to hH3R and hH 4R--a molecular modeling study.

Authors:  Hans-Joachim Wittmann; Roland Seifert; Andrea Strasser
Journal:  J Mol Model       Date:  2014-08-07       Impact factor: 1.810

5.  Induced effects of sodium ions on dopaminergic G-protein coupled receptors.

Authors:  Jana Selent; Ferran Sanz; Manuel Pastor; Gianni De Fabritiis
Journal:  PLoS Comput Biol       Date:  2010-08-12       Impact factor: 4.475

6.  Ligand selectivity of D2 dopamine receptors is modulated by changes in local dynamics produced by sodium binding.

Authors:  Spencer S Ericksen; David F Cummings; Harel Weinstein; John A Schetz
Journal:  J Pharmacol Exp Ther       Date:  2008-10-10       Impact factor: 4.030

Review 7.  Progress in structure based drug design for G protein-coupled receptors.

Authors:  Miles Congreve; Christopher J Langmead; Jonathan S Mason; Fiona H Marshall
Journal:  J Med Chem       Date:  2011-06-15       Impact factor: 7.446

8.  Mathematical analysis of the sodium sensitivity of the human histamine H3 receptor.

Authors:  Hans-Joachim Wittmann; Roland Seifert; Andrea Strasser
Journal:  In Silico Pharmacol       Date:  2014-05-24

9.  Allosteric modulation of dopamine D2L receptor in complex with Gi1 and Gi2 proteins: the effect of subtle structural and stereochemical ligand modifications.

Authors:  Justyna Żuk; Damian Bartuzi; Andrea G Silva; Monika Pitucha; Oliwia Koszła; Tomasz M Wróbel; Dariusz Matosiuk; Marián Castro; Agnieszka A Kaczor
Journal:  Pharmacol Rep       Date:  2022-01-22       Impact factor: 3.024
  9 in total

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