Literature DB >> 1597432

Doublet translocation at GGA is mediated directly by mutant tRNA(2Gly).

F T Pagel1, T M Tuohy, J F Atkins, E J Murgola.   

Abstract

Members of the sufS class of -1 frameshift suppressors have alterations of the GGA/G-decoding tRNA(2Gly). Suppressor-promoted frameshifting at GGA was shown in this study to be directly mediated by the mutant tRNA(2Gly). We disproved the possibility that, in the presence of the compromised mutant tRNA(2Gly), either wild-type tRNA(1Gly), wild-type tRNA(3Gly), a GGA-reading mutant form of tRNA(3Gly), or any other agent suppresses the frameshift mutation trpE91.

Mesh：

Substances：

Year:  1992        PMID： 1597432      PMCID： PMC206132          DOI： 10.1128/jb.174.12.4179-4182.1992

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  12 in total

1.  Glycine tRNA mutants with normal anticodon loop size cause -1 frameshifting.

Authors:  D J O'Mahony; B H Mims; S Thompson; E J Murgola; J F Atkins
Journal:  Proc Natl Acad Sci U S A       Date:  1989-10       Impact factor: 11.205

Review 2.  Towards a genetic dissection of the basis of triplet decoding, and its natural subversion: programmed reading frame shifts and hops.

Authors:  J F Atkins; R B Weiss; S Thompson; R F Gesteland
Journal:  Annu Rev Genet       Date:  1991       Impact factor: 16.830

Review 3.  tRNA, suppression, and the code.

Authors:  E J Murgola
Journal:  Annu Rev Genet       Date:  1985       Impact factor: 16.830

4.  Mutants of translational components that alter reading frame by two steps forward or one step back.

Authors:  M B Falahee; R B Weiss; M O'Connor; S Doonan; R F Gesteland; J F Atkins
Journal:  J Biol Chem       Date:  1988-12-05       Impact factor: 5.157

5.  Suppression of a -1 frameshift mutation by a recessive tRNA suppressor which causes doublet decoding.

Authors:  D J O'Mahony; D Hughes; S Thompson; J F Atkins
Journal:  J Bacteriol       Date:  1989-07       Impact factor: 3.490

6.  The nucleotide sequence of the GGG-specific glycine transfer ribonucleic acid of Escherichia coli and of Salmonella typhimurium.

Authors:  C W Hill; G Combriato; W Steinhart; D L Riddle; J Carbon
Journal:  J Biol Chem       Date:  1973-06-25       Impact factor: 5.157

7.  External suppression of a frameshift mutant in salmonella.

Authors:  S Riyasaty; J F Atkins
Journal:  J Mol Biol       Date:  1968-06-28       Impact factor: 5.469

8.  Glycine transfer RNA of Escherichia coli. II. Impaired GGA-recognition in strains containing a genetically altered transfer RNA; reversal by a secondary suppressor mutation.

Authors:  J Carbon; C Squires; C W Hill
Journal:  J Mol Biol       Date:  1970-09-28       Impact factor: 5.469

9.  Codon recognition by glycine transfer RNAs of Escherichia coli in vivo.

Authors:  E J Murgola; F T Pagel
Journal:  J Mol Biol       Date:  1980-04-25       Impact factor: 5.469

10.  Normal and mutant glycine transfer RNAs.

Authors:  C Squires; J Carbon
Journal:  Nat New Biol       Date:  1971-10-27
View more
  3 in total

1.  Mutations which alter the elbow region of tRNA2Gly reduce T4 gene 60 translational bypassing efficiency.

Authors:  A J Herr; J F Atkins; R F Gesteland
Journal:  EMBO J       Date:  1999-05-17       Impact factor: 11.598

Review 2.  A gripping tale of ribosomal frameshifting: extragenic suppressors of frameshift mutations spotlight P-site realignment.

Authors:  John F Atkins; Glenn R Björk
Journal:  Microbiol Mol Biol Rev       Date:  2009-03       Impact factor: 11.056

3.  Functional tRNAs with altered 3' ends.

Authors:  M O'Connor; N M Willis; L Bossi; R F Gesteland; J F Atkins
Journal:  EMBO J       Date:  1993-06       Impact factor: 11.598
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.