Literature DB >> 15931376

Mapping quantitative trait loci in humans: achievements and limitations.

Partha P Majumder1, Saurabh Ghosh.   

Abstract

Recent advances in statistical methods and genomic technologies have ushered in a new era in mapping clinically important quantitative traits. However, many refinements and novel statistical approaches are required to enable greater successes in this mapping. The possible impact of recent findings pertaining to the structure of the human genome on efforts to map quantitative traits is yet unclear.

Entities:  

Mesh：

Year:  2005        PMID： 15931376      PMCID： PMC1137003          DOI： 10.1172/JCI24757

Source DB:  PubMed          Journal:  J Clin Invest        ISSN： 0021-9738            Impact factor:   14.808


  61 in total

1.  An empirical test of the significance of an observed quantitative trait locus effect that preserves additive genetic variation.

Authors:  S J Iturria; J T Williams; L Almasy; T D Dyer; J Blangero
Journal:  Genet Epidemiol       Date:  1999       Impact factor: 2.135

2.  Haseman and Elston revisited.

Authors:  R C Elston; S Buxbaum; K B Jacobs; J M Olson
Journal:  Genet Epidemiol       Date:  2000-07       Impact factor: 2.135

3.  A genome-wide scan for abdominal fat assessed by computed tomography in the Québec Family Study.

Authors:  L Pérusse; T Rice; Y C Chagnon; J P Després; S Lemieux; S Roy; M Lacaille; M A Ho-Kim; M Chagnon; M A Province; D C Rao; C Bouchard
Journal:  Diabetes       Date:  2001-03       Impact factor: 9.461

4.  A genomewide linkage scan for quantitative-trait loci for obesity phenotypes.

Authors:  Hong-Wen Deng; Hongyi Deng; Yong-Jun Liu; Yao-Zhong Liu; Fu-Hua Xu; Hui Shen; Theresa Conway; Jin-Long Li; Qing-Yang Huang; K M Davies; Robert R Recker
Journal:  Am J Hum Genet       Date:  2002-03-28       Impact factor: 11.025

5.  Equivalence between Haseman-Elston and variance-components linkage analyses for sib pairs.

Authors:  P C Sham; S Purcell
Journal:  Am J Hum Genet       Date:  2001-05-14       Impact factor: 11.025

6.  Integrating sibship data for mapping quantitative trait loci.

Authors:  S Ghosh; T Reich
Journal:  Ann Hum Genet       Date:  2002-03       Impact factor: 1.670

Review 7.  Quantitative trait locus analyses and the study of evolutionary process.

Authors:  David L Erickson; Charles B Fenster; Hans K Stenøien; Donald Price
Journal:  Mol Ecol       Date:  2004-09       Impact factor: 6.185

8.  Descent graphs in pedigree analysis: applications to haplotyping, location scores, and marker-sharing statistics.

Authors:  E Sobel; K Lange
Journal:  Am J Hum Genet       Date:  1996-06       Impact factor: 11.025

9.  Parametric and nonparametric linkage analysis: a unified multipoint approach.

Authors:  L Kruglyak; M J Daly; M P Reeve-Daly; E S Lander
Journal:  Am J Hum Genet       Date:  1996-06       Impact factor: 11.025

10.  Linkage between quantitative trait and marker loci: methods using all relative pairs.

Authors:  J M Olson; E M Wijsman
Journal:  Genet Epidemiol       Date:  1993       Impact factor: 2.135
View more
  13 in total

1.  Amplified fragment length polymorphism mapping of quantitative trait loci for malaria parasite susceptibility in the yellow fever mosquito Aedes aegypti.

Authors:  Daibin Zhong; David M Menge; Emmanuel A Temu; Hong Chen; Guiyun Yan
Journal:  Genetics       Date:  2006-04-19       Impact factor: 4.562

Review 2.  Vaccinomics and a new paradigm for the development of preventive vaccines against viral infections.

Authors:  Gregory A Poland; Inna G Ovsyannikova; Richard B Kennedy; Iana H Haralambieva; Robert M Jacobson
Journal:  OMICS       Date:  2011-07-06

3.  Statistical Optimization of Pharmacogenomics Association Studies: Key Considerations from Study Design to Analysis.

Authors:  Benjamin J Grady; Marylyn D Ritchie
Journal:  Curr Pharmacogenomics Person Med       Date:  2011-03-01

4.  A two-step genetic study on quantitative precursors of coronary artery disease in a homogeneous Indian population: case-control association discovery and validation by transmission-disequilibrium test.

Authors:  Sanjukta Mallik; Partha P Majumder
Journal:  J Biosci       Date:  2011-12       Impact factor: 1.826

Review 5.  Mapping the new frontier: complex genetic disorders.

Authors:  Richard Mayeux
Journal:  J Clin Invest       Date:  2005-06       Impact factor: 14.808

6.  Genome-wide association analyses of quantitative traits: the GAW16 experience.

Authors:  Saurabh Ghosh
Journal:  Genet Epidemiol       Date:  2009       Impact factor: 2.135

Review 7.  Application of pharmacogenomics to vaccines.

Authors:  Gregory A Poland; Inna G Ovsyannikova; Robert M Jacobson
Journal:  Pharmacogenomics       Date:  2009-05       Impact factor: 2.533

8.  Family-based mapping of quantitative trait loci in plant breeding populations with resistance to Fusarium head blight in wheat as an illustration.

Authors:  U R Rosyara; J L Gonzalez-Hernandez; K D Glover; K R Gedye; J M Stein
Journal:  Theor Appl Genet       Date:  2009-03-26       Impact factor: 5.699

9.  Separation of base allele and sampling term effects gives new insights in variance component QTL analysis.

Authors:  Lars Rönnegård; Orjan Carlborg
Journal:  BMC Genet       Date:  2007-01-08       Impact factor: 2.797

10.  Genotype matrix mapping: searching for quantitative trait loci interactions in genetic variation in complex traits.

Authors:  Sachiko Isobe; Akihiro Nakaya; Satoshi Tabata
Journal:  DNA Res       Date:  2007-11-13       Impact factor: 4.458
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.