Literature DB >> 15931170

Miniaturization in functional genomics and proteomics.

Sascha Sauer1, Bodo M H Lange, Johan Gobom, Lajos Nyarsik, Harald Seitz, Hans Lehrach.   

Abstract

Proteins are the key components of the cellular machinery responsible for processing changes that are ordered by genomic information. Analysis of most human proteins and nucleic acids is important in order to decode the complex networks that are likely to underlie many common diseases. Significant improvements in current technology are also required to dissect the regulatory processes in high-throughtput and with low cost. Miniaturization of biological assays is an important prerequisite to achieve these goals in the near future.

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Year:  2005        PMID: 15931170     DOI: 10.1038/nrg1618

Source DB:  PubMed          Journal:  Nat Rev Genet        ISSN: 1471-0056            Impact factor:   53.242


  28 in total

1.  Single molecule transcription profiling with AFM.

Authors:  Jason Reed; Bud Mishra; Bede Pittenger; Sergei Magonov; Joshua Troke; Michael A Teitell; James K Gimzewski
Journal:  Nanotechnology       Date:  2007-05-09       Impact factor: 3.874

2.  High-throughput injection with microfluidics using picoinjectors.

Authors:  Adam R Abate; Tony Hung; Pascaline Mary; Jeremy J Agresti; David A Weitz
Journal:  Proc Natl Acad Sci U S A       Date:  2010-10-20       Impact factor: 11.205

3.  Observing the invisible through imaging mass spectrometry, a window into the metabolic exchange patterns of microbes.

Authors:  David J Gonzalez; Yuquan Xu; Yu-Liang Yang; Eduardo Esquenazi; Wei-Ting Liu; Anna Edlund; Tram Duong; Liangcheng Du; István Molnár; William H Gerwick; Paul R Jensen; Michael Fischbach; Chih-Chuang Liaw; Paul Straight; Victor Nizet; Pieter C Dorrestein
Journal:  J Proteomics       Date:  2012-05-26       Impact factor: 4.044

Review 4.  Novel susceptibility genes in inflammatory bowel disease.

Authors:  Colin Noble; Elaine Nimmo; Daniel Gaya; Richard K Russell; Jack Satsangi
Journal:  World J Gastroenterol       Date:  2006-04-07       Impact factor: 5.742

Review 5.  Microfluidic cartridges preloaded with nanoliter plugs of reagents: an alternative to 96-well plates for screening.

Authors:  Delai L Chen; Rustem F Ismagilov
Journal:  Curr Opin Chem Biol       Date:  2006-05-03       Impact factor: 8.822

6.  Nanoliter microfluidic hybrid method for simultaneous screening and optimization validated with crystallization of membrane proteins.

Authors:  Liang Li; Debarshi Mustafi; Qiang Fu; Valentina Tereshko; Delai L Chen; Joshua D Tice; Rustem F Ismagilov
Journal:  Proc Natl Acad Sci U S A       Date:  2006-12-11       Impact factor: 11.205

Review 7.  Proteomic approaches to dissect platelet function: Half the story.

Authors:  Dmitri V Gnatenko; Peter L Perrotta; Wadie F Bahou
Journal:  Blood       Date:  2006-08-22       Impact factor: 22.113

8.  Phylogenetic classification and identification of bacteria by mass spectrometry.

Authors:  Anja Freiwald; Sascha Sauer
Journal:  Nat Protoc       Date:  2009       Impact factor: 13.491

Review 9.  Mass spectrometry tools for the classification and identification of bacteria.

Authors:  Sascha Sauer; Magdalena Kliem
Journal:  Nat Rev Microbiol       Date:  2010-01       Impact factor: 60.633

Review 10.  Genetic dissection of platelet function in health and disease using systems biology.

Authors:  Wadie F Bahou
Journal:  Hematol Oncol Clin North Am       Date:  2013-04-09       Impact factor: 3.722

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