OBJECTIVES: To determine whether mechanical percussion, diuresis, and inversion (PDI) therapy after shock wave lithotripsy (SWL) improves the clearance rates of lower pole renal stones. METHODS: In this single-blind study, 108 patients who underwent SWL treatment for lower pole renal stones with a total diameter of 2 cm or less were prospectively randomized into two groups. One group (n = 49) received SWL only and the other group (n = 59) received a median of four sessions of PDI therapy (range 1 to 12), 1 to 2 weeks after each SWL session. PDI therapy was performed as follows. Patients drank 500 mL of water 30 minutes before therapy; they then lay in a prone Trendelenburg position on a 45 degrees -angle couch, and received continuous 10-minute manual mechanical percussion applied over the flank. Stone clearance was documented with plain abdominal radiography, with additional imaging, if indicated, 1 and 3 months after initial SWL therapy. RESULTS: The patients from both groups were comparable in terms of total stone diameter, infundibular neck diameter, infundibular length, caliceal height, infundibular-pelvic angles, infundibular-ureteral angles, infundibular-vertebral angles, lower pole cortical thickness, and caliceal number. All patients underwent a maximum of four SWL treatments. For all assessable patients, the radiologically documented complete stone clearance rate at 3 months for the SWL-alone group was 35.4% and for the SWL plus PDI group was 62.5% (chi-square test, P = 0.006). CONCLUSIONS:PDI therapy is a valuable adjunct in assisting passage of lower pole renal stone fragments after SWL therapy.
RCT Entities:
OBJECTIVES: To determine whether mechanical percussion, diuresis, and inversion (PDI) therapy after shock wave lithotripsy (SWL) improves the clearance rates of lower pole renal stones. METHODS: In this single-blind study, 108 patients who underwent SWL treatment for lower pole renal stones with a total diameter of 2 cm or less were prospectively randomized into two groups. One group (n = 49) received SWL only and the other group (n = 59) received a median of four sessions of PDI therapy (range 1 to 12), 1 to 2 weeks after each SWL session. PDI therapy was performed as follows. Patients drank 500 mL of water 30 minutes before therapy; they then lay in a prone Trendelenburg position on a 45 degrees -angle couch, and received continuous 10-minute manual mechanical percussion applied over the flank. Stone clearance was documented with plain abdominal radiography, with additional imaging, if indicated, 1 and 3 months after initial SWL therapy. RESULTS: The patients from both groups were comparable in terms of total stone diameter, infundibular neck diameter, infundibular length, caliceal height, infundibular-pelvic angles, infundibular-ureteral angles, infundibular-vertebral angles, lower pole cortical thickness, and caliceal number. All patients underwent a maximum of four SWL treatments. For all assessable patients, the radiologically documented complete stone clearance rate at 3 months for the SWL-alone group was 35.4% and for the SWL plus PDI group was 62.5% (chi-square test, P = 0.006). CONCLUSIONS: PDI therapy is a valuable adjunct in assisting passage of lower pole renal stone fragments after SWL therapy.
Authors: Jonathan D Harper; Mathew D Sorensen; Bryan W Cunitz; Yak-Nam Wang; Julianna C Simon; Frank Starr; Marla Paun; Barbrina Dunmire; H Denny Liggitt; Andrew P Evan; James A McAteer; Ryan S Hsi; Michael R Bailey Journal: J Urol Date: 2013-04-09 Impact factor: 7.450