Literature DB >> 15921419

Cytotoxic arylnaphthalene lignans from a Vietnamese acanthaceae, Justicia patentiflora.

Sophie Susplugas1, Nguyen Van Hung, Jérôme Bignon, Odile Thoison, Anna Kruczynski, Thierry Sévenet, Françoise Guéritte.   

Abstract

One new norlignan (1) and five new lignans (2-6) were isolated from the leaves and stems of Justicia patentiflora by a bioassay-guided purification. Five known compounds, carinatone, diphyllin, justicidin A, taiwanin E, and tuberculatin, were also found in J. patentiflora. Most of the new compounds display significant activity in in vitro cytotoxic assays against KB, HCT116, and MCF-7 cancer cell lines and arrest the cell cycle in the G0/G1 phase.

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Year:  2005        PMID： 15921419     DOI： 10.1021/np050028u

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  12 in total

1.  D11, a novel glycosylated diphyllin derivative, exhibits potent anticancer activity by targeting topoisomerase IIα.

Authors:  Min Gui; Da-Kuo Shi; Min Huang; Yu Zhao; Qi-Ming Sun; Jing Zhang; Qin Chen; Jian-Ming Feng; Chun-Hong Liu; Ming Li; Ying-Xia Li; Meiyu Geng; Jian Ding
Journal:  Invest New Drugs       Date:  2010-03-25       Impact factor: 3.850

2.  Potential Anticancer Agents Characterized from Selected Tropical Plants.

Authors:  Yulin Ren; Esperanza J Carcache de Blanco; James R Fuchs; Djaja D Soejarto; Joanna E Burdette; Steven M Swanson; A Douglas Kinghorn
Journal:  J Nat Prod       Date:  2019-03-04       Impact factor: 4.050

3.  Synthesis and antiproliferative activity of derivatives of the phyllanthusmin class of arylnaphthalene lignan lactones.

Authors:  John L Woodard; Andrew C Huntsman; Pratiq A Patel; Hee-Byung Chai; Ragu Kanagasabai; Soumendrakrishna Karmahapatra; Alexandria N Young; Yulin Ren; Malcolm S Cole; Denisse Herrera; Jack C Yalowich; A Douglas Kinghorn; Joanna E Burdette; James R Fuchs
Journal:  Bioorg Med Chem       Date:  2018-03-23       Impact factor: 3.641

4.  A novel topoisomerase inhibitor, daurinol, suppresses growth of HCT116 cells with low hematological toxicity compared to etoposide.

Authors:  Kyungsu Kang; Seung Hyun Oh; Ji Ho Yun; Eun Hye Jho; Ju-Hee Kang; Dulamjav Batsuren; Jigjidsuren Tunsag; Kwang Hwa Park; Minkyun Kim; Chu Won Nho
Journal:  Neoplasia       Date:  2011-11       Impact factor: 5.715

5.  Elenoside increases intestinal motility.

Authors:  E Navarro; S-J Alonso; R Navarro; J Trujillo; E Jorge
Journal:  World J Gastroenterol       Date:  2006-11-28       Impact factor: 5.742

6.  Evaluation and structure-activity relationship analysis of a new series of arylnaphthalene lignans as potential anti-tumor agents.

Authors:  Jiaoyang Luo; Yichen Hu; Weijun Kong; Meihua Yang
Journal:  PLoS One       Date:  2014-03-27       Impact factor: 3.240

7.  Anti-Inflammatory and Antinociceptive Studies of Hydroalcoholic Extract from the Leaves of Phyllanthus brasiliensis (Aubl.) Poir. and Isolation of 5-O-β-d-Glucopyranosyljusticidin B and Six Other Lignans.

Authors:  Luziane da C Borges; Raimundo Negrão-Neto; Sônia Pamplona; Luanna Fernandes; Mayra Barros; Enéas Fontes-Júnior; Cristiane Maia; Consuelo Y Yoshioka E Silva; Milton Nascimento da Silva
Journal:  Molecules       Date:  2018-04-18       Impact factor: 4.411

8.  Potent cytotoxic arylnaphthalene lignan lactones from Phyllanthus poilanei.

Authors:  Yulin Ren; Daniel D Lantvit; Youcai Deng; Ragu Kanagasabai; Judith C Gallucci; Tran Ngoc Ninh; Hee-Byung Chai; Djaja D Soejarto; James R Fuchs; Jack C Yalowich; Jianhua Yu; Steven M Swanson; A Douglas Kinghorn
Journal:  J Nat Prod       Date:  2014-06-12       Impact factor: 4.050

9.  Glycosylated diphyllin as a broad-spectrum antiviral agent against Zika virus.

Authors:  Alicia Martinez-Lopez; Mirjana Persaud; Maritza Puray Chavez; Hongjie Zhang; Lijun Rong; Shufeng Liu; Tony T Wang; Stefan G Sarafianos; Felipe Diaz-Griffero
Journal:  EBioMedicine       Date:  2019-09-06       Impact factor: 8.143

Review 10.  Lignans and Their Derivatives from Plants as Antivirals.

Authors:  Qinghua Cui; Ruikun Du; Miaomiao Liu; Lijun Rong
Journal:  Molecules       Date:  2020-01-01       Impact factor: 4.411
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