Literature DB >> 15908405

Endogenous interleukin-6 plays a crucial protective role in streptococcal toxic shock syndrome via suppression of tumor necrosis factor alpha production.

Hongyan Diao1, Masashi Kohanawa.   

Abstract

During a Streptococcus pyogenes infection in interleukin-6 (IL-6)-deficient mice, there is elevation of serum tumor necrosis factor alpha (TNF-alpha) levels, muscular necrosis, and death compared with infection of C57BL/6 mice. Anti-TNF-alpha monoclonal antibody treatment decreased mortality and muscular necrosis in the infected IL-6-deficient mice. These results suggest that IL-6 plays a crucial protective role via suppression of TNF-alpha production in S. pyogenes infection.

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Year:  2005        PMID： 15908405      PMCID： PMC1111866          DOI： 10.1128/IAI.73.6.3745-3748.2005

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  18 in total

1.  Effect of anti-IL-6 and anti-10 monoclonal antibodies on the suppression of the normal T lymphocyte mitogenic response by steady state sickle cell disease sera.

Authors:  S Taylor; S Shacks; Z Qu
Journal:  Immunol Invest       Date:  2001-08       Impact factor: 3.657

2.  Epidemiology of invasive group a streptococcus disease in the United States, 1995-1999.

Authors:  Katherine L O'Brien; Bernard Beall; Nancy L Barrett; Paul R Cieslak; Arthur Reingold; Monica M Farley; Richard Danila; Elizabeth R Zell; Richard Facklam; Benjamin Schwartz; Anne Schuchat
Journal:  Clin Infect Dis       Date:  2002-07-10       Impact factor: 9.079

3.  Epidemiological and clinical aspects of invasive group A streptococcal infections and the streptococcal toxic shock syndrome.

Authors:  B K Eriksson; J Andersson; S E Holm; M Norgren
Journal:  Clin Infect Dis       Date:  1998-12       Impact factor: 9.079

4.  Growth hormone down-regulation of Interleukin-1beta and Interleukin-6 induced acute phase protein gene expression is associated with increased gene expression of suppressor of cytokine signal-3.

Authors:  Xiaowu Wu; David N Herndon; Steven E Wolf
Journal:  Shock       Date:  2003-04       Impact factor: 3.454

5.  Lipopolysaccharide triggers invasive streptococcal disease in mice through a tumour necrosis factor-alpha-dependent mechanism.

Authors:  Hongyan Diao; Masashi Kohanawa; Hirofumi Nakajima; Yuichiro Sato; Tomonori Minagawa; Akio Nakane
Journal:  Immunology       Date:  2002-03       Impact factor: 7.397

6.  Distinct IL-6 signal transduction leads to growth arrest and death in B cells or growth promotion and cell survival in myeloma cells.

Authors:  W-C Cheung; B Van Ness
Journal:  Leukemia       Date:  2002-06       Impact factor: 11.528

7.  Pathogenic role of interleukin-6 in the development of sepsis. Part II: Significance of anti-interleukin-6 and anti-soluble interleukin-6 receptor-alpha antibodies in a standardized murine contact burn model.

Authors:  Norbert Pallua; Janina F A Low; Dennis von Heimburg
Journal:  Crit Care Med       Date:  2003-05       Impact factor: 7.598

8.  IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages.

Authors:  Hideo Yasukawa; Masanobu Ohishi; Hiroyuki Mori; Masaaki Murakami; Takatoshi Chinen; Daisuke Aki; Toshikatsu Hanada; Kiyoshi Takeda; Shizuo Akira; Masahiko Hoshijima; Toshio Hirano; Kenneth R Chien; Akihiko Yoshimura
Journal:  Nat Immunol       Date:  2003-05-18       Impact factor: 25.606

9.  Invasive group A streptococcal infections in Ontario, Canada. Ontario Group A Streptococcal Study Group.

Authors:  H D Davies; A McGeer; B Schwartz; K Green; D Cann; A E Simor; D E Low
Journal:  N Engl J Med       Date:  1996-08-22       Impact factor: 91.245

10.  Correlation between serum TNF alpha and IL6 levels and severity of group A streptococcal infections.

Authors:  A Norrby-Teglund; K Pauksens; M Norgren; S E Holm
Journal:  Scand J Infect Dis       Date:  1995
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  19 in total

1.  Anaphylaxis and mortality induced by treatment of mice with anti-VLA-4 antibody and pertussis toxin.

Authors:  Niannian Ji; Nagarjun Rao; Neal M Guentzel; Bernard P Arulanandam; Thomas G Forsthuber
Journal:  J Immunol       Date:  2011-01-26       Impact factor: 5.422

2.  Antioxidative and Immunomodulatory Potential of the Endemic French Guiana Wild Cocoa "Guiana".

Authors:  Elodie Jean-Marie; Didier Bereau; Patrick Poucheret; Caroline Guzman; Frederic Boudard; Jean-Charles Robinson
Journal:  Foods       Date:  2021-03-03

3.  Aberrant inflammatory response to Streptococcus pyogenes in mice lacking myeloid differentiation factor 88.

Authors:  Torsten G Loof; Oliver Goldmann; André Gessner; Heiko Herwald; Eva Medina
Journal:  Am J Pathol       Date:  2009-12-17       Impact factor: 4.307

Review 4.  The varying faces of IL-6: From cardiac protection to cardiac failure.

Authors:  Jillian A Fontes; Noel R Rose; Daniela Čiháková
Journal:  Cytokine       Date:  2015-01-31       Impact factor: 3.861

5.  Autoimmunity as a predisposition for infectious diseases.

Authors:  Mohan S Maddur; Janakiraman Vani; Sébastien Lacroix-Desmazes; Srinivas Kaveri; Jagadeesh Bayry
Journal:  PLoS Pathog       Date:  2010-11-04       Impact factor: 6.823

6.  Staphylococcus aureus Fatty Acid Kinase FakA Modulates Pathogenesis during Skin Infection via Proteases.

Authors:  Miranda J Ridder; Seth M Daly; Kathleen D Triplett; Nichole A Seawell; Pamela R Hall; Jeffrey L Bose
Journal:  Infect Immun       Date:  2020-07-21       Impact factor: 3.441

7.  Prognostic value and therapeutic potential of TREM-1 in Streptococcus pyogenes- induced sepsis.

Authors:  Sarah A Horst; Anna Linnér; Andreas Beineke; Sabine Lehne; Claudia Höltje; Alexander Hecht; Anna Norrby-Teglund; Eva Medina; Oliver Goldmann
Journal:  J Innate Immun       Date:  2013-04-04       Impact factor: 7.349

8.  Opportunistic Invasive Infection by Group A Streptococcus During Anti-Interleukin-6 Immunotherapy.

Authors:  Shyra Wilde; Katherine L Olivares; Victor Nizet; Hal M Hoffman; Suhas Radhakrishna; Christopher N LaRock
Journal:  J Infect Dis       Date:  2021-04-08       Impact factor: 5.226

9.  Alterations in the Expression Profile of Serum miR-155, miR-223, miR-17, miR-200a, miR-205, as well as Levels of Interleukin 6, and Prostaglandins during Endometritis in Arabian Mares.

Authors:  Sally Ibrahim; Mohamed Hedia; Mohamed O Taqi; Mohamed K Derbala; Karima Gh M Mahmoud; Youssef Ahmed; Sayed Ismail; Mohamed El-Belely
Journal:  Vet Sci       Date:  2021-06-04

10.  Intratracheal IL-6 protects against lung inflammation in direct, but not indirect, causes of acute lung injury in mice.

Authors:  Rhea Bhargava; William Janssen; Christopher Altmann; Ana Andrés-Hernando; Kayo Okamura; R William Vandivier; Nilesh Ahuja; Sarah Faubel
Journal:  PLoS One       Date:  2013-05-08       Impact factor: 3.240
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