Literature DB >> 15908219

Heteroarylisopropylamines as MAO inhibitors.

Gabriel Vallejos1, Angélica Fierro, Marcos Caroli Rezende, Silvia Sepúlveda-Boza, Miguel Reyes-Parada.   

Abstract

The in vitro monoamine oxidase inhibitory (MAOI) activities of 11 heteroarylisopropylamines vis-à-vis MAO-A and MAO-B were described and interpreted in terms of possible interactions with the enzyme active site. Molecular dynamics simulations allowed a comparison between the most active MAO-A inhibitor of the series, the 1-(2-benzofuryl)-2-aminopropane, and the specific, analogous MAO-A substrate serotonin.

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Year:  2005        PMID： 15908219     DOI： 10.1016/j.bmc.2005.04.045

Source DB:  PubMed          Journal:  Bioorg Med Chem        ISSN： 0968-0896            Impact factor:   3.641


  9 in total

1.  (E)-2-(2-Nitro-prop-1-en-yl)furan.

Authors:  Pedro Valerga; M Carmen Puerta; Zenaida Rodríguez Negrín; Nilo Castañedo Cancio; Miguel Palma Lovillo
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2009-07-31

2.  (E)-2-(2-Nitro-ethen-yl)furan.

Authors:  Pedro Valerga; M Carmen Puerta; Zenaida Rodríguez Negrín; Nilo Castañedo Cancio; Miguel Palma Lovillo
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2009-07-25

3.  Ethylenedioxy homologs of N-methyl-(3,4-methylenedioxyphenyl)-2-aminopropane (MDMA) and its corresponding cathinone analog methylenedioxymethcathinone: Interactions with transporters for serotonin, dopamine, and norepinephrine.

Authors:  Fabio Del Bello; Farhana Sakloth; John S Partilla; Michael H Baumann; Richard A Glennon
Journal:  Bioorg Med Chem       Date:  2015-07-23       Impact factor: 3.641

4.  Human and rat monoamine oxidase-A are differentially inhibited by (S)-4-alkylthioamphetamine derivatives: insights from molecular modeling studies.

Authors:  Angélica Fierro; Mauricio Osorio-Olivares; Bruce K Cassels; Dale E Edmondson; Silvia Sepúlveda-Boza; Miguel Reyes-Parada
Journal:  Bioorg Med Chem       Date:  2007-05-22       Impact factor: 3.641

5.  (E)-1-Bromo-4-(2-nitro-prop-1-en-yl)benzene.

Authors:  Bailin Li
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2009-11-21

6.  Evaluation of the Abuse Potential of Novel Amphetamine Derivatives with Modifications on the Amine (NBNA) and Phenyl (EDA, PMEA, 2-APN) Sites.

Authors:  Raly James Perez Custodio; Chrislean Jun Botanas; Seong Shoon Yoon; June Bryan de la Peña; Irene Joy Dela Peña; Mikyung Kim; Taeseon Woo; Joung-Wook Seo; Choon-Gon Jang; Yong Ho Kwon; Nam Yong Kim; Yong Sup Lee; Hee Jin Kim; Jae Hoon Cheong
Journal:  Biomol Ther (Seoul)       Date:  2017-11-01       Impact factor: 4.634

Review 7.  Amphetamine Derivatives as Monoamine Oxidase Inhibitors.

Authors:  Miguel Reyes-Parada; Patricio Iturriaga-Vasquez; Bruce K Cassels
Journal:  Front Pharmacol       Date:  2020-01-23       Impact factor: 5.810

8.  Comparative Neuropharmacology and Pharmacokinetics of Methamphetamine and Its Thiophene Analog Methiopropamine in Rodents.

Authors:  Silja Skogstad Tuv; Marianne Skov-Skov Bergh; Jannike Mørch Andersen; Synne Steinsland; Vigdis Vindenes; Michael H Baumann; Marilyn A Huestis; Inger Lise Bogen
Journal:  Int J Mol Sci       Date:  2021-11-05       Impact factor: 5.923

9.  Syntheses and analytical characterizations of novel (2-aminopropyl)benzo[b]thiophene (APBT) based stimulants.

Authors:  Simon D Brandt; Laura Carlino; Pierce V Kavanagh; Folker Westphal; Wolfgang Dreiseitel; Geraldine Dowling; Michael H Baumann; Harald H Sitte; Adam L Halberstadt
Journal:  Drug Test Anal       Date:  2020-06-10       Impact factor: 3.234
  9 in total

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