Literature DB >> 15900501

Single nucleotide polymorphisms within the promoter region of the rhesus monkey tumor necrosis factor-alpha gene.

Krishna K Singh1, Jörg Schmidtke.   

Abstract

The human TNF-alpha gene is characterized by several single nucleotide polymorphisms (SNPs) in its promoter region, in part having been shown to influence TNF-alpha expression and susceptibility to various diseases. The rhesus macaque is widely used as an animal model for a variety of TNF-alpha associated pathological conditions, but little is known about genetic variation within the TNF-alpha promoter region. In order to check for such polymorphisms, primers based on rhesus sequence within 5' UTR were designed and used to amplify a approximately 1 kb product from genomic DNA of 29 animals. Sequencing and cloning revealed a total of 11 polymorphisms leading to five different haplotypes.

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Year:  2005        PMID： 15900501     DOI： 10.1007/s00251-005-0799-x

Source DB:  PubMed          Journal:  Immunogenetics        ISSN： 0093-7711            Impact factor:   2.846


  13 in total

1.  Functional consequences of a polymorphism affecting NF-kappaB p50-p50 binding to the TNF promoter region.

Authors:  I A Udalova; A Richardson; A Denys; C Smith; H Ackerman; B Foxwell; D Kwiatkowski
Journal:  Mol Cell Biol       Date:  2000-12       Impact factor: 4.272

Review 2.  Remitting-relapsing EAE in nonhuman primates: a valid model of multiple sclerosis.

Authors:  L M Rose; T L Richards; R Petersen; J Peterson; S Hruby; E C Alvord
Journal:  Clin Immunol Immunopathol       Date:  1991-04

Review 3.  Major histocompatibility complex class II polymorphisms in primates.

Authors:  R E Bontrop; N Otting; N G de Groot; G G Doxiadis
Journal:  Immunol Rev       Date:  1999-02       Impact factor: 12.988

4.  Vaccine protection against functional CTL abnormalities in simian human immunodeficiency virus-infected rhesus monkeys.

Authors:  Paul F McKay; Jörn E Schmitz; Dan H Barouch; Marcelo J Kuroda; Michelle A Lifton; Christine E Nickerson; Darci A Gorgone; Norman L Letvin
Journal:  J Immunol       Date:  2002-01-01       Impact factor: 5.422

5.  A new primate model for multiple sclerosis in the common marmoset.

Authors:  B A 't Hart; M van Meurs; H P Brok; L Massacesi; J Bauer; L Boon; R E Bontrop; J D Laman
Journal:  Immunol Today       Date:  2000-06

6.  Effects of in vitro ethanol on tumor necrosis factor-alpha production by blood obtained from simian immunodeficiency virus-infected rhesus macaques.

Authors:  David A Stoltz; Steve Nelson; Jay K Kolls; Ping Zhang; Rudolf P Bohm; Michael Murphey-Corb; Gregory J Bagby
Journal:  Alcohol Clin Exp Res       Date:  2002-04       Impact factor: 3.455

7.  A polymorphism that affects OCT-1 binding to the TNF promoter region is associated with severe malaria.

Authors:  J C Knight; I Udalova; A V Hill; B M Greenwood; N Peshu; K Marsh; D Kwiatkowski
Journal:  Nat Genet       Date:  1999-06       Impact factor: 38.330

8.  Differential tumor necrosis factor alpha production in simian immunodeficiency virus-infected rhesus macaques coinfected with Mycobacterium avium.

Authors:  G W Newman; D L Adams; J N Maslow; M Murphy-Corb; P J Didier
Journal:  Clin Infect Dis       Date:  1999-03       Impact factor: 9.079

9.  Identification of phylogenetic footprints in primate tumor necrosis factor-alpha promoters.

Authors:  J Y Leung; F E McKenzie; A M Uglialoro; P O Flores-Villanueva; B C Sorkin; E J Yunis; D L Hartl; A E Goldfeld
Journal:  Proc Natl Acad Sci U S A       Date:  2000-06-06       Impact factor: 11.205

10.  Evidence for a rhesus monkey model of asymptomatic tuberculosis.

Authors:  Bobby J Gormus; James L Blanchard; Xavier H Alvarez; Peter J Didier
Journal:  J Med Primatol       Date:  2004-06       Impact factor: 0.667
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  2 in total

1.  Positive selection of Toll-like receptor 2 polymorphisms in two closely related old world monkey species, rhesus and Japanese macaques.

Authors:  Akiko Takaki; Akiko Yamazaki; Tomoyuki Maekawa; Hiroki Shibata; Kenji Hirayama; Akinori Kimura; Hirohisa Hirai; Michio Yasunami
Journal:  Immunogenetics       Date:  2011-07-09       Impact factor: 2.846

2.  Comparative analyses of single-nucleotide polymorphisms in the TNF promoter region provide further validation for the vervet monkey model of obesity.

Authors:  Stanton B Gray; Timothy D Howard; Carl D Langefeld; Gregory A Hawkins; Abdoulaye F Diallo; Janice D Wagner
Journal:  Comp Med       Date:  2009-12       Impact factor: 0.982
  2 in total

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