| Literature DB >> 10825741 |
B A 't Hart1, M van Meurs, H P Brok, L Massacesi, J Bauer, L Boon, R E Bontrop, J D Laman.
Abstract
Experimental autoimmune encephalomyelitis (EAE) in outbred marmoset monkeys (Callithrix jacchus) is a recently developed nonhuman primate model of multiple sclerosis. Here, Bert 't Hart and colleagues compare this model to EAE in rhesus monkeys, highlighting autoimmune mechanisms in CNS inflammation and demyelination, including the role of major histocompatibility complex restriction and preclinical evaluation of innovative immunotherapies.Entities:
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Year: 2000 PMID: 10825741 DOI: 10.1016/s0167-5699(00)01627-3
Source DB: PubMed Journal: Immunol Today ISSN: 0167-5699