Literature DB >> 15884789

Structure-activity relationship studies of chemical mutagens and carcinogens: mechanistic investigations and prediction approaches.

Romualdo Benigni1.   

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Year:  2005        PMID： 15884789     DOI： 10.1021/cr030049y

Source DB:  PubMed          Journal:  Chem Rev        ISSN： 0009-2665            Impact factor:   60.622


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  19 in total

1.  Some findings relevant to the mechanistic interpretation in the case of predictive models for carcinogenicity based on the counter propagation artificial neural network.

Authors:  Natalja Fjodorova; Marjana Novič
Journal:  J Comput Aided Mol Des       Date:  2011-12-03       Impact factor: 3.686

Review 2.  Molecular mechanisms underlying chemical liver injury.

Authors:  Xinsheng Gu; Jose E Manautou
Journal:  Expert Rev Mol Med       Date:  2012-02-03       Impact factor: 5.600

3.  Improving prediction of carcinogenicity to reduce, refine, and replace the use of experimental animals.

Authors:  Todd Bourcier; Tim McGovern; Lidiya Stavitskaya; Naomi Kruhlak; David Jacobson-Kram
Journal:  J Am Assoc Lab Anim Sci       Date:  2015-03       Impact factor: 1.232

4.  Lazy structure-activity relationships (lazar) for the prediction of rodent carcinogenicity and Salmonella mutagenicity.

Authors:  Christoph Helma
Journal:  Mol Divers       Date:  2006-05-24       Impact factor: 2.943

5.  Quantitative and qualitative models for carcinogenicity prediction for non-congeneric chemicals using CP ANN method for regulatory uses.

Authors:  Natalja Fjodorova; Marjan Vračko; Marjan Tušar; Aneta Jezierska; Marjana Novič; Ralph Kühne; Gerrit Schüürmann
Journal:  Mol Divers       Date:  2009-08-15       Impact factor: 2.943

6.  Prediction of carcinogenicity for diverse chemicals based on substructure grouping and SVM modeling.

Authors:  Kazutoshi Tanabe; Bono Lučić; Dragan Amić; Takio Kurita; Mikio Kaihara; Natsuo Onodera; Takahiro Suzuki
Journal:  Mol Divers       Date:  2010-02-26       Impact factor: 2.943

7.  QSAR modeling for predicting mutagenic toxicity of diverse chemicals for regulatory purposes.

Authors:  Nikita Basant; Shikha Gupta
Journal:  Environ Sci Pollut Res Int       Date:  2017-04-24       Impact factor: 4.223

8.  Metabolic and electrochemical mechanisms of dimeric naphthoquinones cytotoxicity in breast cancer cells.

Authors:  Ashkan Emadi; Anne Le; Cynthia J Harwood; Kenneth W Stagliano; Farin Kamangar; Ashley E Ross; Charles R Cooper; Chi V Dang; Judith E Karp; Milena Vuica-Ross
Journal:  Bioorg Med Chem       Date:  2011-10-08       Impact factor: 3.641

9.  Design and Synthesis of a Novel and Selective Kappa Opioid Receptor (KOR) Antagonist (BTRX-335140).

Authors:  Miguel Guerrero; Mariangela Urbano; Eun-Kyong Kim; Ana M Gamo; Sean Riley; Lusine Abgaryan; Nora Leaf; Lori Jean Van Orden; Steven J Brown; Jennifer Y Xie; Frank Porreca; Michael D Cameron; Hugh Rosen; Edward Roberts
Journal:  J Med Chem       Date:  2019-02-13       Impact factor: 7.446

Review 10.  Integrative approaches for predicting in vivo effects of chemicals from their structural descriptors and the results of short-term biological assays.

Authors:  Yen Sia Low; Alexander Yeugenyevich Sedykh; Ivan Rusyn; Alexander Tropsha
Journal:  Curr Top Med Chem       Date:  2014       Impact factor: 3.295
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