Literature DB >> 15864062

Case report: Reconstruction of an intercalary defect with bone transport after resection of Ewing's sarcoma.

John P Dormans1, Onder Ofluoglu, Bulent Erol, Leslie Moroz, Richard S Davidson.   

Abstract

We report a 13-year-old girl with Ewing's sarcoma of the tibia who was treated with multiagent chemotherapy, followed by local control tumor surgery consisting of wide resection of the tumor and bone transport with distraction osteogenesis for reconstruction. The bone defect created by resection was 13 cm long and was replaced by bone transport using a monolateral external fixator. Evaluation of the resected specimen revealed wide tumor-free margins with 100% chemonecrosis. A planned Harmon-type autogenous bone grafting between the middle and proximal segments of the tibia (docking site) was done primarily after docking occurred, and a solid union was obtained by 23 months after resection. The bone healing index (treatment index) was 54 days/1 cm distraction, which is indicative of slow healing. Clinical evaluation of the affected extremity using the Musculoskeletal Tumor Society rating system revealed 80% normal functional capability. Indications for bone transport in reconstruction of bone defects created by wide resection of bone sarcomas are discussed. In retrospect, we have concerns regarding the suitability of this technique in the setting of diaphyseal sarcoma reconstruction in patients with Ewing's sarcoma who require aggressive and intense multiagent chemotherapy.

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Year:  2005        PMID: 15864062     DOI: 10.1097/01.blo.0000152898.03736.40

Source DB:  PubMed          Journal:  Clin Orthop Relat Res        ISSN: 0009-921X            Impact factor:   4.176


  7 in total

1.  Is the Induced-membrane Technique Successful for Limb Reconstruction After Resecting Large Bone Tumors in Children?

Authors:  Frank Fitoussi; Brice Ilharreborde
Journal:  Clin Orthop Relat Res       Date:  2015-01-30       Impact factor: 4.176

2.  Outcomes of a Modular Intercalary Endoprosthesis as Treatment for Segmental Defects of the Femur, Tibia, and Humerus.

Authors:  Joseph Benevenia; Rainer Kirchner; Francis Patterson; Kathleen Beebe; Dieter C Wirtz; Steven Rivero; Mark Palma; Max J Friedrich
Journal:  Clin Orthop Relat Res       Date:  2016-02       Impact factor: 4.176

3.  Outcomes of Intercalary Prosthetic Reconstruction for Pathological Diaphyseal Femoral Fractures Secondary to Metastatic Tumors.

Authors:  Hong-Chao Huang; Yong-Cheng Hu; Deng-Xing Lun; Jun Miao; Feng Wang; Xiong-Gang Yang; Xin-Long Ma
Journal:  Orthop Surg       Date:  2017-06-09       Impact factor: 2.071

4.  Resection arthrodesis using distraction osteogenesis then plating as a hybrid surgical technique for the management of bone sarcomas of the distal tibia.

Authors:  Teng-Fei Lou; Hua Li; Yi-Min Chai; Chun-Yang Wang; Sheng-He Liu; Musha Hamushan; Fan Wu; Wei-Jie Cai; Pei Han
Journal:  Int Orthop       Date:  2018-02-03       Impact factor: 3.075

5.  Case report: reconstruction of a 16-cm diaphyseal defect after Ewing's resection in a child.

Authors:  David Jean Biau; Stéphanie Pannier; Alain Charles Masquelet; Christophe Glorion
Journal:  Clin Orthop Relat Res       Date:  2008-11-14       Impact factor: 4.176

6.  Efficacy of a Modified Scoring System to Facilitate Surgical Decision-making for Diaphyseal Malignancies: When is Devitalized Tumor-bearing Autograft of Value?

Authors:  Yu Chen; Xiu-Chun Yu
Journal:  Orthop Surg       Date:  2019-08-11       Impact factor: 2.071

7.  Short-term outcomes of reconstruction subsequent to intercalary resection of femoral diaphyseal metastatic tumor with pathological fracture: Comparison between segmental allograft and intercalary prosthesis.

Authors:  Deng-Xing Lun; Yong-Cheng Hu; Xiong-Gang Yang; Feng Wang; Zhao-Wan Xu
Journal:  Oncol Lett       Date:  2018-01-16       Impact factor: 2.967

  7 in total

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