Literature DB >> 15845528

Interleukin-15 enhances innate and adaptive immune responses to blood-stage malaria infection in mice.

Rebecca Ing1, Philippe Gros, Mary M Stevenson.   

Abstract

Compared to C57BL/6 wild-type mice, interleukin-15(-/-) (IL-15(-/-)) mice showed delayed clearance of Plasmodium chabaudi AS infection, lower type 1 cytokine production, impaired dendritic cell and NK cell functions, and lower titers of malaria-specific antibodies. Thus, IL-15 supports early control and timely resolution of blood-stage malaria through promotion of Th1-dependent innate and adaptive immune responses.

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Year:  2005        PMID： 15845528      PMCID： PMC1087354          DOI： 10.1128/IAI.73.5.3172-3177.2005

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  40 in total

Review 1.  Rodent malarias: the mouse as a model for understanding immune responses and pathology induced by the erythrocytic stages of the parasite.

Authors:  C Li; E Seixas; J Langhorne
Journal:  Med Microbiol Immunol       Date:  2001-04       Impact factor: 3.402

2.  Complicated malaria is associated with differential elevations in serum levels of interleukins 10, 12, and 15.

Authors:  P Gosi; S Khusmith; S Looareesuwan; U Sitachamroom; R Glanarongran; K Buchachart; D S Walsh
Journal:  Southeast Asian J Trop Med Public Health       Date:  1999-09       Impact factor: 0.267

3.  Down-regulation of IL-12 p40 gene in Plasmodium berghei-infected mice.

Authors:  X Xu; K Sumita; C Feng; X Xiong; H Shen; S Maruyama; M Kanoh; Y Asano
Journal:  J Immunol       Date:  2001-07-01       Impact factor: 5.422

4.  The complexity of protective immunity against liver-stage malaria.

Authors:  D L Doolan; S L Hoffman
Journal:  J Immunol       Date:  2000-08-01       Impact factor: 5.422

5.  Endogenous IL-15 might be responsible for early protection by natural killer cells against infection with an avirulent strain of Salmonella choleraesuis in mice.

Authors:  K Hirose; H Nishimura; T Matsuguchi; Y Yoshikai
Journal:  J Leukoc Biol       Date:  1999-09       Impact factor: 4.962

Review 6.  Modulation of host responses to blood-stage malaria by interleukin-12: from therapy to adjuvant activity.

Authors:  M M Stevenson; Z Su; H Sam; K Mohan
Journal:  Microbes Infect       Date:  2001-01       Impact factor: 2.700

7.  Central role of endogenous gamma interferon in protective immunity against blood-stage Plasmodium chabaudi AS infection.

Authors:  Z Su; M M Stevenson
Journal:  Infect Immun       Date:  2000-08       Impact factor: 3.441

8.  Cytokine production and killer activity of NK/T-NK cells derived with IL-2, IL-15, or the combination of IL-12 and IL-18.

Authors:  B R Lauwerys; N Garot; J C Renauld; F A Houssiau
Journal:  J Immunol       Date:  2000-08-15       Impact factor: 5.422

9.  Differential roles of interleukin 15 mRNA isoforms generated by alternative splicing in immune responses in vivo.

Authors:  H Nishimura; T Yajima; Y Naiki; H Tsunobuchi; M Umemura; K Itano; T Matsuguchi; M Suzuki; P S Ohashi; Y Yoshikai
Journal:  J Exp Med       Date:  2000-01-03       Impact factor: 14.307

10.  Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice.

Authors:  M K Kennedy; M Glaccum; S N Brown; E A Butz; J L Viney; M Embers; N Matsuki; K Charrier; L Sedger; C R Willis; K Brasel; P J Morrissey; K Stocking; J C Schuh; S Joyce; J J Peschon
Journal:  J Exp Med       Date:  2000-03-06       Impact factor: 14.307
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  14 in total

Review 1.  The role of interleukin-15 in inflammation and immune responses to infection: implications for its therapeutic use.

Authors:  Pin-Yu Perera; Jack H Lichy; Thomas A Waldmann; Liyanage P Perera
Journal:  Microbes Infect       Date:  2011-10-25       Impact factor: 2.700

2.  Responses to Leishmania donovani in mice deficient in interleukin-12 (IL-12), IL-12/IL-23, or IL-18.

Authors:  Henry W Murray; Christine W Tsai; Jianguo Liu; Xiaojing Ma
Journal:  Infect Immun       Date:  2006-07       Impact factor: 3.441

Review 3.  Revealing the molecular signatures of host-pathogen interactions.

Authors:  Chiea-Chuen Khor; Martin L Hibberd
Journal:  Genome Biol       Date:  2011-10-19       Impact factor: 13.583

Review 4.  Host resistance to malaria: using mouse models to explore the host response.

Authors:  Rhea Longley; Clare Smith; Anny Fortin; Joanne Berghout; Brendan McMorran; Gaétan Burgio; Simon Foote; Philippe Gros
Journal:  Mamm Genome       Date:  2010-11-30       Impact factor: 2.957

5.  Signalling through the IL-2 receptor γ(c) peptide (CD132) is essential for the expression of immunity to Plasmodium chabaudi adami blood-stage malaria.

Authors:  W P Weidanz; G Lafleur; A Kita-Yarbro; K Nelson; J M Burns
Journal:  Parasite Immunol       Date:  2011-09       Impact factor: 2.280

6.  Involvement of gonadal steroids and gamma interferon in sex differences in response to blood-stage malaria infection.

Authors:  Amy Cernetich; Lindsey S Garver; Anne E Jedlicka; Pamela W Klein; Nirbhay Kumar; Alan L Scott; Sabra L Klein
Journal:  Infect Immun       Date:  2006-06       Impact factor: 3.441

7.  The survival of memory CD8 T cells that is mediated by IL-15 correlates with sustained protection against malaria.

Authors:  Stasya Zarling; Dmitriy Berenzon; Sarat Dalai; Dmitry Liepinsh; Nick Steers; Urszula Krzych
Journal:  J Immunol       Date:  2013-04-15       Impact factor: 5.422

8.  Dendritic cell and NK cell reciprocal cross talk promotes gamma interferon-dependent immunity to blood-stage Plasmodium chabaudi AS infection in mice.

Authors:  Rebecca Ing; Mary M Stevenson
Journal:  Infect Immun       Date:  2008-11-17       Impact factor: 3.441

9.  Reduced Parasite Burden in Children with Falciparum Malaria and Bacteremia Coinfections: Role of Mediators of Inflammation.

Authors:  Gregory C Davenport; James B Hittner; Vincent Otieno; Zachary Karim; Harshini Mukundan; Paul W Fenimore; Nicolas W Hengartner; Benjamin H McMahon; Prakasha Kempaiah; John M Ong'echa; Douglas J Perkins
Journal:  Mediators Inflamm       Date:  2016-06-22       Impact factor: 4.711

Review 10.  NK Cells: Uncertain Allies against Malaria.

Authors:  Asia-Sophia Wolf; Samuel Sherratt; Eleanor M Riley
Journal:  Front Immunol       Date:  2017-03-09       Impact factor: 7.561
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