Literature DB >> 16790814

Responses to Leishmania donovani in mice deficient in interleukin-12 (IL-12), IL-12/IL-23, or IL-18.

Henry W Murray1, Christine W Tsai, Jianguo Liu, Xiaojing Ma.   

Abstract

Interleukin-12 (IL-12) orchestrates acquired resistance in intracellular Leishmania donovani infection in the liver, inducing gamma interferon and, in turn, macrophage activation and parasite killing. Nevertheless, testing in IL-18(-/-) mice compared to wild-type mice and in IL-12p40(-/-) compared to IL-12p35(-/-) mice also suggested both early-acting (IL-18) and late-acting (IL-23) antileishmanial effects independent of IL-12.

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Year:  2006        PMID： 16790814      PMCID： PMC1489747          DOI： 10.1128/IAI.00422-06

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  36 in total

1.  Interleukin-12 regulates the response to chemotherapy in experimental visceral Leishmaniasis.

Authors:  H W Murray; C Montelibano; R Peterson; J P Sypek
Journal:  J Infect Dis       Date:  2000-10-09       Impact factor: 5.226

Review 2.  New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions.

Authors:  Christopher A Hunter
Journal:  Nat Rev Immunol       Date:  2005-07       Impact factor: 53.106

3.  Prevention of relapse after chemotherapy in a chronic intracellular infection: mechanisms in experimental visceral leishmaniasis.

Authors:  Henry W Murray
Journal:  J Immunol       Date:  2005-04-15       Impact factor: 5.422

4.  Genetically resistant mice lacking IL-18 gene develop Th1 response and control cutaneous Leishmania major infection.

Authors:  G M Monteforte; K Takeda; M Rodriguez-Sosa; S Akira; J R David; A R Satoskar
Journal:  J Immunol       Date:  2000-06-01       Impact factor: 5.422

5.  IL-12 gene-deficient C57BL/6 mice are susceptible to Leishmania donovani but have diminished hepatic immunopathology.

Authors:  A R Satoskar; S Rodig; S R Telford; A A Satoskar; S K Ghosh; F von Lichtenberg; J R David
Journal:  Eur J Immunol       Date:  2000-03       Impact factor: 5.532

6.  IL-23 compensates for the absence of IL-12p70 and is essential for the IL-17 response during tuberculosis but is dispensable for protection and antigen-specific IFN-gamma responses if IL-12p70 is available.

Authors:  Shabaana A Khader; John E Pearl; Kaori Sakamoto; Leigh Gilmartin; Guy K Bell; Dawn M Jelley-Gibbs; Nico Ghilardi; Fred deSauvage; Andrea M Cooper
Journal:  J Immunol       Date:  2005-07-15       Impact factor: 5.422

Review 7.  Immunopathogenesis of infection with the visceralizing Leishmania species.

Authors:  Mary E Wilson; Selma M B Jeronimo; Richard D Pearson
Journal:  Microb Pathog       Date:  2005-04       Impact factor: 3.738

8.  Interleukin-27R (WSX-1/T-cell cytokine receptor) gene-deficient mice display enhanced resistance to leishmania donovani infection but develop severe liver immunopathology.

Authors:  Lucia E Rosas; Anjali A Satoskar; Kimberly M Roth; Tracy L Keiser; Joseph Barbi; Christopher Hunter; Frederic J de Sauvage; Abhay R Satoskar
Journal:  Am J Pathol       Date:  2006-01       Impact factor: 4.307

9.  Roles of endogenous gamma interferon and macrophage microbicidal mechanisms in host response to chemotherapy in experimental visceral leishmaniasis.

Authors:  H W Murray; S Delph-Etienne
Journal:  Infect Immun       Date:  2000-01       Impact factor: 3.441

10.  Visceral leishmaniasis in mice devoid of tumor necrosis factor and response to treatment.

Authors:  H W Murray; A Jungbluth; E Ritter; C Montelibano; M W Marino
Journal:  Infect Immun       Date:  2000-11       Impact factor: 3.441
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  17 in total

1.  Gamma Interferon-Regulated Chemokines in Leishmania donovani Infection in the Liver.

Authors:  Henry W Murray; Andrew D Luster; Hua Zheng; Xiaojing Ma
Journal:  Infect Immun       Date:  2016-12-29       Impact factor: 3.441

2.  Granzyme-mediated regulation of host defense in the liver in experimental Leishmania donovani infection.

Authors:  Henry W Murray; Marisa Mitchell-Flack; Hua Zheng; Xiaojing Ma
Journal:  Infect Immun       Date:  2014-12-01       Impact factor: 3.441

3.  BAY 41-2272, a soluble guanylate cyclase agonist, activates human mononuclear phagocytes.

Authors:  P V Soeiro-Pereira; A Falcai; C A Kubo; E B Oliveira-Júnior; O C Marques; E Antunes; A Condino-Neto
Journal:  Br J Pharmacol       Date:  2012-07       Impact factor: 8.739

4.  Antileishmanial effect of 18β-glycyrrhetinic acid is mediated by Toll-like receptor-dependent canonical and noncanonical p38 activation.

Authors:  Purnima Gupta; Pijush K Das; Anindita Ukil
Journal:  Antimicrob Agents Chemother       Date:  2015-02-17       Impact factor: 5.191

5.  Temporal regulation of interleukin-12p70 (IL-12p70) and IL-12-related cytokines in splenic dendritic cell subsets during Leishmania donovani infection.

Authors:  Asher Maroof; Paul M Kaye
Journal:  Infect Immun       Date:  2007-11-12       Impact factor: 3.441

6.  Accelerated control of visceral Leishmania donovani infection in interleukin-6-deficient mice.

Authors:  Henry W Murray
Journal:  Infect Immun       Date:  2008-06-23       Impact factor: 3.441

7.  STAT4 is critical for immunity but not for antileishmanial activity of antimonials in experimental visceral leishmaniasis.

Authors:  Steve Oghumu; Gaurav Gupta; Heidi M Snider; Sanjay Varikuti; César A Terrazas; Tracey L Papenfuss; Mark H Kaplan; Abhay R Satoskar
Journal:  Eur J Immunol       Date:  2013-11-15       Impact factor: 5.532

8.  Neutrophils contribute to development of a protective immune response during onset of infection with Leishmania donovani.

Authors:  Emma McFarlane; Cynthia Perez; Mélanie Charmoy; Cindy Allenbach; K Christine Carter; James Alexander; Fabienne Tacchini-Cottier
Journal:  Infect Immun       Date:  2007-12-03       Impact factor: 3.441

9.  Classification and regression tree and spatial analyses reveal geographic heterogeneity in genome wide linkage study of Indian visceral leishmaniasis.

Authors:  Michaela Fakiola; Anshuman Mishra; Madhukar Rai; Shri Prakash Singh; Rebecca A O'Leary; Stephen Ball; Richard W Francis; Martin J Firth; Ben T Radford; E Nancy Miller; Shyam Sundar; Jenefer M Blackwell
Journal:  PLoS One       Date:  2010-12-31       Impact factor: 3.240

10.  VCAM-1 and VLA-4 modulate dendritic cell IL-12p40 production in experimental visceral leishmaniasis.

Authors:  Amanda C Stanley; Jane E Dalton; Susanna H Rossotti; Kelli P MacDonald; Yonghong Zhou; Fabian Rivera; Wayne A Schroder; Asher Maroof; Geoff R Hill; Paul M Kaye; Christian R Engwerda
Journal:  PLoS Pathog       Date:  2008-09-19       Impact factor: 6.823
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