Literature DB >> 15835722

Retymicin, galtamycin B, saquayamycin Z and ribofuranosyllumichrome, novel secondary metabolites from Micromonospora sp. Tü 6368. II. Structure elucidation.

Karsten Ströch1, Axel Zeeck, Noémi Antal, Hans-Peter Fiedler.   

Abstract

A detailed screening of the secondary metabolite pattern from Micromonospora sp. strain Tü 6368 resulted in the isolation of ten compounds belonging to five different structural families. The structures of the novel compounds 1-(alpha-ribofuranosyl)-lumichrome (3), retymicin (7), galtamycin B (11) and saquayamycin Z (14) were assigned by spectroscopic methods and chemical transformations. This strain fits our hypothesis that the metabolite analysis of biosynthetically talented strains leads readily to novel compounds.

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Year:  2005        PMID： 15835722     DOI： 10.1038/ja.2005.13

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  11 in total

Review 1.  A comprehensive review of glycosylated bacterial natural products.

Authors:  Sherif I Elshahawi; Khaled A Shaaban; Madan K Kharel; Jon S Thorson
Journal:  Chem Soc Rev       Date:  2015-11-07       Impact factor: 54.564

2.  Bioprospecting Micromonospora from Kaziranga National Park of India and their anti-infective potential.

Authors:  Madhumita Talukdar; Aparajita Duarah; Shruti Talukdar; Manorama Bura Gohain; Rajal Debnath; Archana Yadav; Dhruva K Jha; Tarun C Bora
Journal:  World J Microbiol Biotechnol       Date:  2012-05-29       Impact factor: 3.312

3.  Properties of lanK-based regulatory circuit involved in landomycin biosynthesis in Streptomyces cyanogenus S136.

Authors:  B Ostash; I Ostash; L Zhu; M K Kharel; A Luzhetskiĭ; A Bechthold; S Walker; J Rohr; V Fedorenko
Journal:  Genetika       Date:  2010-05

4.  Cytotoxic rearranged angucycline glycosides from deep sea-derived Streptomyces lusitanus SCSIO LR32.

Authors:  Xiangcheng Zhu; Yanwen Duan; Zhaomeng Cui; Zhen Wang; Zengxia Li; Yun Zhang; Jianhua Ju; Hongbo Huang
Journal:  J Antibiot (Tokyo)       Date:  2017-02-22       Impact factor: 2.649

5.  Cytotoxic Indolocarbazoles from Actinomadura melliaura ATCC 39691.

Authors:  Khaled A Shaaban; Sherif I Elshahawi; Xiachang Wang; Jamie Horn; Madan K Kharel; Markos Leggas; Jon S Thorson
Journal:  J Nat Prod       Date:  2015-06-19       Impact factor: 4.050

6.  Reagent Controlled Direct Dehydrative Glycosylation with 2-Deoxy Sugars: Construction of the Saquayamycin Z Pentasaccharide.

Authors:  J Colin Mizia; Clay S Bennett
Journal:  Org Lett       Date:  2019-07-15       Impact factor: 6.005

7.  Saquayamycins G-K, cytotoxic angucyclines from Streptomyces sp. Including two analogues bearing the aminosugar rednose.

Authors:  Khaled A Shaaban; Tamer A Ahmed; Markos Leggas; Jürgen Rohr
Journal:  J Nat Prod       Date:  2012-07-03       Impact factor: 4.050

8.  Moromycins A and B, isolation and structure elucidation of C-glycosylangucycline-type antibiotics from Streptomyces sp. KY002.

Authors:  Mohamed S Abdelfattah; Madan Kumar Kharel; John Andrew Hitron; Irfan Baig; Jürgen Rohr
Journal:  J Nat Prod       Date:  2008-07-31       Impact factor: 4.050

9.  Two Streptomyces species producing antibiotic, antitumor, and anti-inflammatory compounds are widespread among intertidal macroalgae and deep-sea coral reef invertebrates from the central Cantabrian Sea.

Authors:  Alfredo F Braña; Afredo F Braña; Hans-Peter Fiedler; Herminio Nava; Verónica González; Aida Sarmiento-Vizcaíno; Axayacatl Molina; José L Acuña; Luis A García; Gloria Blanco
Journal:  Microb Ecol       Date:  2014-10-16       Impact factor: 4.552

10.  Pharmacological Potential of Phylogenetically Diverse Actinobacteria Isolated from Deep-Sea Coral Ecosystems of the Submarine Avilés Canyon in the Cantabrian Sea.

Authors:  Aida Sarmiento-Vizcaíno; Verónica González; Alfredo F Braña; Juan J Palacios; Luis Otero; Jonathan Fernández; Axayacatl Molina; Andreas Kulik; Fernando Vázquez; José L Acuña; Luis A García; Gloria Blanco
Journal:  Microb Ecol       Date:  2016-09-10       Impact factor: 4.552
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