Literature DB >> 15833131

SINEs point to abundant editing in the human genome.

Joshua DeCerbo1, Gordon G Carmichael.   

Abstract

Recent bioinformatic analyses suggest that almost all human transcripts are edited by adenosine deaminases (ADARs), converting adenosines to inosines. Most of this editing is in Alu element transcripts, which are unique to primates. This editing might have no function or might be involved in functions such as the regulation of splicing, chromatin or nuclear localization of transcripts.

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Year:  2005        PMID： 15833131      PMCID： PMC1088953          DOI： 10.1186/gb-2005-6-4-216

Source DB:  PubMed          Journal:  Genome Biol        ISSN： 1474-7596            Impact factor:   13.583


  23 in total

1.  A cis-acting element in the 3'-untranslated region of human TNF-alpha mRNA renders splicing dependent on the activation of protein kinase PKR.

Authors:  F Osman; N Jarrous; Y Ben-Asouli; R Kaempfer
Journal:  Genes Dev       Date:  1999-12-15       Impact factor: 11.361

2.  The fate of dsRNA in the nucleus: a p54(nrb)-containing complex mediates the nuclear retention of promiscuously A-to-I edited RNAs.

Authors:  Z Zhang; G G Carmichael
Journal:  Cell       Date:  2001-08-24       Impact factor: 41.582

3.  Specific cleavage of hyper-edited dsRNAs.

Authors:  A D Scadden; C W Smith
Journal:  EMBO J       Date:  2001-08-01       Impact factor: 11.598

Review 4.  RNA editing by adenosine deaminases that act on RNA.

Authors:  Brenda L Bass
Journal:  Annu Rev Biochem       Date:  2001-11-09       Impact factor: 23.643

5.  The birth of an alternatively spliced exon: 3' splice-site selection in Alu exons.

Authors:  Galit Lev-Maor; Rotem Sorek; Noam Shomron; Gil Ast
Journal:  Science       Date:  2003-05-23       Impact factor: 47.728

6.  Enrichment for histone H3 lysine 9 methylation at Alu repeats in human cells.

Authors:  Yutaka Kondo; Jean-Pierre J Issa
Journal:  J Biol Chem       Date:  2003-04-30       Impact factor: 5.157

7.  Vigilins bind to promiscuously A-to-I-edited RNAs and are involved in the formation of heterochromatin.

Authors:  Qiaoqiao Wang; Zuo Zhang; Katherine Blackwell; Gordon G Carmichael
Journal:  Curr Biol       Date:  2005-02-22       Impact factor: 10.834

8.  RNAi is antagonized by A-->I hyper-editing.

Authors:  A D Scadden; C W Smith
Journal:  EMBO Rep       Date:  2001-11-21       Impact factor: 8.807

Review 9.  Mammalian retroelements.

Authors:  Prescott L Deininger; Mark A Batzer
Journal:  Genome Res       Date:  2002-10       Impact factor: 9.043

10.  Nervous system targets of RNA editing identified by comparative genomics.

Authors:  Barry Hoopengardner; Tarun Bhalla; Cynthia Staber; Robert Reenan
Journal:  Science       Date:  2003-08-08       Impact factor: 47.728
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  11 in total

1.  Alu element-mediated gene silencing.

Authors:  Ling-Ling Chen; Joshua N DeCerbo; Gordon G Carmichael
Journal:  EMBO J       Date:  2008-05-22       Impact factor: 11.598

2.  Nascent-seq indicates widespread cotranscriptional RNA editing in Drosophila.

Authors:  Joseph Rodriguez; Jerome S Menet; Michael Rosbash
Journal:  Mol Cell       Date:  2012-05-31       Impact factor: 17.970

3.  Alu RNA and their roles in human disease states.

Authors:  Daniel Gussakovsky; Sean A McKenna
Journal:  RNA Biol       Date:  2021-10-21       Impact factor: 4.766

4.  mRNA expression, splicing and editing in the embryonic and adult mouse cerebral cortex.

Authors:  Allissa A Dillman; David N Hauser; J Raphael Gibbs; Michael A Nalls; Melissa K McCoy; Iakov N Rudenko; Dagmar Galter; Mark R Cookson
Journal:  Nat Neurosci       Date:  2013-02-17       Impact factor: 24.884

5.  Breakpoint characterization of large deletions in EXT1 or EXT2 in 10 multiple osteochondromas families.

Authors:  Ivy Jennes; Danielle de Jong; Kirsten Mees; Pancras C W Hogendoorn; Karoly Szuhai; Wim Wuyts
Journal:  BMC Med Genet       Date:  2011-06-26       Impact factor: 2.103

6.  The human genome: a multifractal analysis.

Authors:  Pedro A Moreno; Patricia E Vélez; Ember Martínez; Luis E Garreta; Néstor Díaz; Siler Amador; Irene Tischer; José M Gutiérrez; Ashwinikumar K Naik; Fabián Tobar; Felipe García
Journal:  BMC Genomics       Date:  2011-10-14       Impact factor: 3.969

7.  RNA-editing-mediated exon evolution.

Authors:  Galit Lev-Maor; Rotem Sorek; Erez Y Levanon; Nurit Paz; Eli Eisenberg; Gil Ast
Journal:  Genome Biol       Date:  2007       Impact factor: 13.583

8.  The possible roles of human Alu elements in aging.

Authors:  O E Mustafina
Journal:  Front Genet       Date:  2013-05-28       Impact factor: 4.599

9.  Alu-directed transcriptional regulation of some novel miRNAs.

Authors:  Tong J Gu; Xiang Yi; Xi W Zhao; Yi Zhao; James Q Yin
Journal:  BMC Genomics       Date:  2009-11-30       Impact factor: 3.969

10.  Intronic Alus influence alternative splicing.

Authors:  Galit Lev-Maor; Oren Ram; Eddo Kim; Noa Sela; Amir Goren; Erez Y Levanon; Gil Ast
Journal:  PLoS Genet       Date:  2008-09-26       Impact factor: 5.917
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