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Literature DB >> 15827839

Role of systematic reviews and meta-analysis in evidence-based medicine.

Abstract

The overwhelming increase in the quantity of clinical evidence has led to detachment of the evidence and practice because new evidence can be integrated into clinical practice only after it has been critically appraised and synthesized on the basis of the existing evidence. Because many clinicians lack the skills and the time for such information processing, systematic reviews and meta-analyses, their quantitative counterparts, play an important role in health care. Well performed systematic reviews provide clinically relevant information for surgeons, abrogating the need to identify, read, and evaluate many individual studies. This article reviews the basic principles of meta-analysis, discusses its potential weaknesses such as heterogeneity and publication bias, and highlights special situations when dealing with surgical trials.

Entities: Disease

Mesh：

Year: 2005 PMID： 15827839 DOI： 10.1007/s00268-005-7917-7

Source DB: PubMed Journal: World J Surg ISSN： 0364-2313 Impact factor: 3.352

32 in total

1. How relevant are the systematic reviews in the cochrane library to emergency medical practice?

Authors: Stephen D Emond; Peter C Wyer; Michael D Brown; William H Cordell; Carol H Spooner; Brian H Rowe
Journal: Ann Emerg Med Date: 2002-02 Impact factor: 5.721

2. Investigating causes of heterogeneity in systematic reviews.

Authors: P P Glasziou; S L Sanders
Journal: Stat Med Date: 2002-06-15 Impact factor: 2.373

3. Issues in the selection of a summary statistic for meta-analysis of clinical trials with binary outcomes.

Authors: Jonathan J Deeks
Journal: Stat Med Date: 2002-06-15 Impact factor: 2.373

4. [The practice of evidence-based medicine in surgery--evidence and experience].

Authors: Stefan Sauerland; Bertil Bouillon; Edmund Neugebauer
Journal: Z Arztl Fortbild Qualitatssich Date: 2003-07

5. The existence of publication bias and risk factors for its occurrence.

Authors: K Dickersin
Journal: JAMA Date: 1990-03-09 Impact factor: 56.272

6. Does quality of reports of randomised trials affect estimates of intervention efficacy reported in meta-analyses?

Authors: D Moher; B Pham; A Jones; D J Cook; A R Jadad; M Moher; P Tugwell; T P Klassen
Journal: Lancet Date: 1998-08-22 Impact factor: 79.321

7. Why review articles on the health effects of passive smoking reach different conclusions.

Authors: D E Barnes; L A Bero
Journal: JAMA Date: 1998-05-20 Impact factor: 56.272

8. The Cochrane Collaboration. Preparing, maintaining, and disseminating systematic reviews of the effects of health care.

Authors: L Bero; D Rennie
Journal: JAMA Date: 1995-12-27 Impact factor: 56.272

Review 9. Why sources of heterogeneity in meta-analysis should be investigated.

Authors: S G Thompson
Journal: BMJ Date: 1994-11-19

Review 10. Laparoscopic versus open surgery for suspected appendicitis.

Authors: S Sauerland; R Lefering; E A Neugebauer
Journal: Cochrane Database Syst Rev Date: 2002

17 in total

1. Evidence-based medicine--from best research evidence to a better surgical practice and health care.

Authors: G Antes; S Sauerland; C M Seiler
Journal: Langenbecks Arch Surg Date: 2005-11-16 Impact factor: 3.445

2. Securing the appendiceal stump in laparoscopic appendectomy: evidence for routine stapling?

Authors: G Kazemier; K H in't Hof; S Saad; H J Bonjer; S Sauerland
Journal: Surg Endosc Date: 2006-07-03 Impact factor: 4.584

3. Clinical effectiveness of selective granulocyte, monocyte adsorptive apheresis with the Adacolumn device in ulcerative colitis.

Authors: Brigitte Habermalz; Stefan Sauerland
Journal: Dig Dis Sci Date: 2009-06-11 Impact factor: 3.199

Role of systematic reviews and meta-analysis in evidence-based medicine.

1. How relevant are the systematic reviews in the cochrane library to emergency medical practice?

2. Investigating causes of heterogeneity in systematic reviews.

3. Issues in the selection of a summary statistic for meta-analysis of clinical trials with binary outcomes.

4. [The practice of evidence-based medicine in surgery--evidence and experience].

5. The existence of publication bias and risk factors for its occurrence.

6. Does quality of reports of randomised trials affect estimates of intervention efficacy reported in meta-analyses?

7. Why review articles on the health effects of passive smoking reach different conclusions.

8. The Cochrane Collaboration. Preparing, maintaining, and disseminating systematic reviews of the effects of health care.

Review 9. Why sources of heterogeneity in meta-analysis should be investigated.

Review 10. Laparoscopic versus open surgery for suspected appendicitis.

1. Evidence-based medicine--from best research evidence to a better surgical practice and health care.

2. Securing the appendiceal stump in laparoscopic appendectomy: evidence for routine stapling?

3. Clinical effectiveness of selective granulocyte, monocyte adsorptive apheresis with the Adacolumn device in ulcerative colitis.

4. [Systematic reviews and meta-analyses in surgery].

5. [The work of the Cochrane Collaboration in urology].

6. The focus of Langenbeck's Archives of Surgery in the 21st century.

7. Meta-analyses of lightweight versus conventional (heavy weight) mesh in inguinal hernia surgery.

8. Systematic review and meta-analysis: a primer.

9. Antipsychotic use in dementia: a systematic review of benefits and risks from meta-analyses.

10. Critical appraisal of meta-analyses: an introductory guide for the practicing surgeon.