BACKGROUND: Recent studies provide conflicting information about gastroschisis prevalence trends. The authors proposed that prevalence of gastroschisis in live births has increased in Utah and that characteristics of these infants would provide clinically useful information about treatment and outcomes. METHODS: Primary Children's Medical Center (PCMC) is the sole pediatric surgical referral hospital for Utah. The authors used both pediatric surgical and neonatal databases to identify gastroschisis cases at PCMC from 1971 through 2002. Only infants whose mothers had a primary residence in Utah were included. Individual charts were reviewed for infant characteristics for cases from 1998 through 2002. Utah Vital Statistics Reports were used to determine live birth rates and general infant and maternal characteristics. RESULTS: Gastroschisis prevalence increased from 0.36 to 3.92 cases per 10,000 live births over 31 years (P < .001). Young maternal age, primigravida status, and tobacco use were associated risk factors. Using the time required to achieve full enteric feedings at targeted volume and caloric density as a measurement of outcome, we found no association between delivery mode or surgical closure type (primary or secondary) and time to full feedings. Higher birth weight was associated with decreased time to full feedings (P = .03). CONCLUSIONS: Gastroschisis prevalence has increased 10-fold over the past 3 decades in Utah.
BACKGROUND: Recent studies provide conflicting information about gastroschisis prevalence trends. The authors proposed that prevalence of gastroschisis in live births has increased in Utah and that characteristics of these infants would provide clinically useful information about treatment and outcomes. METHODS: Primary Children's Medical Center (PCMC) is the sole pediatric surgical referral hospital for Utah. The authors used both pediatric surgical and neonatal databases to identify gastroschisis cases at PCMC from 1971 through 2002. Only infants whose mothers had a primary residence in Utah were included. Individual charts were reviewed for infant characteristics for cases from 1998 through 2002. Utah Vital Statistics Reports were used to determine live birth rates and general infant and maternal characteristics. RESULTS:Gastroschisis prevalence increased from 0.36 to 3.92 cases per 10,000 live births over 31 years (P < .001). Young maternal age, primigravida status, and tobacco use were associated risk factors. Using the time required to achieve full enteric feedings at targeted volume and caloric density as a measurement of outcome, we found no association between delivery mode or surgical closure type (primary or secondary) and time to full feedings. Higher birth weight was associated with decreased time to full feedings (P = .03). CONCLUSIONS:Gastroschisis prevalence has increased 10-fold over the past 3 decades in Utah.
Authors: Sadie L Williams; Matthew Leonard; Eric S Hall; Jose Perez; Jacqueline Wessel; Paul S Kingma Journal: Am J Perinatol Date: 2017-10-30 Impact factor: 1.862
Authors: Mahsa M Yazdy; Martha M Werler; Marcia L Feldkamp; Gary M Shaw; Bridget S Mosley; Veronica M Vieira Journal: Birth Defects Res A Clin Mol Teratol Date: 2015-04-06
Authors: Erin B Stallings; Jennifer L Isenburg; Tyiesha D Short; Dominique Heinke; Russell S Kirby; Paul A Romitti; Mark A Canfield; Leslie A O'Leary; Rebecca F Liberman; Nina E Forestieri; Wendy N Nembhard; Theresa Sandidge; Eirini Nestoridi; Jason L Salemi; Amy E Nance; Kirstan Duckett; Glenda M Ramirez; Xiaoyi Shan; Jing Shi; Philip J Lupo Journal: Birth Defects Res Date: 2019-10-23 Impact factor: 2.344
Authors: Oliver B Lao; Cindy Larison; Michelle M Garrison; John H T Waldhausen; Adam B Goldin Journal: Am J Perinatol Date: 2009-10-28 Impact factor: 1.862
Authors: Marcia L Feldkamp; Jennita Reefhuis; James Kucik; Sergey Krikov; Andy Wilson; Cynthia A Moore; John C Carey; Lorenzo D Botto Journal: BMJ Date: 2008-06-16