Literature DB >> 15783183

Cell-permeable near-infrared fluorogenic substrates for imaging beta-lactamase activity.

Bengang Xing1, Ashot Khanamiryan, Jianghong Rao.   

Abstract

This communication describes a design of cell-permeable near-infrared fluorogenic substrates for imaging beta-lactamase expression in living mammalian cells. This design is based on fluorescence energy transfer resonance and utilizes a peracetylated d-glucosamine to facilitate the transport of the near-infrared probe across cell membranes. This new type of fluorogenic probe may also be applied to image gene expression in living animals.

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Year:  2005        PMID： 15783183     DOI： 10.1021/ja042829+

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  29 in total

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2.  Quantitative detection of cells expressing BlaC using droplet-based microfluidics for use in the diagnosis of tuberculosis.

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4.  Novel beta-lactamase-random peptide fusion libraries for phage display selection of cancer cell-targeting agents suitable for enzyme prodrug therapy.

Authors:  Girja S Shukla; David N Krag
Journal:  J Drug Target       Date:  2010-02       Impact factor: 5.121

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Journal:  Chembiochem       Date:  2014-04-24       Impact factor: 3.164

6.  A cephalosporin-chemiluminescent conjugate increases beta-lactamase detection sensitivity by four orders of magnitude.

Authors:  Santanu Maity; Xiaojian Wang; Subhamoy Das; Maomao He; Lee W Riley; Niren Murthy
Journal:  Chem Commun (Camb)       Date:  2020-02-26       Impact factor: 6.222

7.  Cancer cell-specific internalizing ligands from phage displayed beta-lactamase-peptide fusion libraries.

Authors:  Girja S Shukla; David N Krag
Journal:  Protein Eng Des Sel       Date:  2010-03-10       Impact factor: 1.650

8.  Phage-displayed combinatorial peptide libraries in fusion to beta-lactamase as reporter for an accelerated clone screening: Potential uses of selected enzyme-linked affinity reagents in downstream applications.

Authors:  Girja S Shukla; David N Krag
Journal:  Comb Chem High Throughput Screen       Date:  2010-01       Impact factor: 1.339

9.  Reporter enzyme fluorescence (REF) imaging and quantification of tuberculosis in live animals.

Authors:  Ying Kong; Jeffrey D Cirillo
Journal:  Virulence       Date:  2010-11-01       Impact factor: 5.882

10.  Rapid point-of-care detection of the tuberculosis pathogen using a BlaC-specific fluorogenic probe.

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Journal:  Nat Chem       Date:  2012-09-02       Impact factor: 24.427
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