BACKGROUND: The ideal mesh for laparoscopic ventral hernia repair is not yet identified. METHODS: We laparoscopically placed polypropylene (PPM), expanded polytetrafluoroethylene (ePTFE), and polyester with antiadhesive collagen layer (PCO) in eight pigs using sutures and tacks for fixation. After 28-day survival, we compared adhesion formation, fibrous ingrowth, and shrinkage among the types of mesh. RESULTS: Mean area of adhesions to PCO (8.25%) was less than that to ePTFE (57.14%, p < 0.001) or PPM (79.38%, p < 0.001). Adhesions peel strength was less for PCO (2.3 N) than for PPM (16.1 N, p < 0.001) or ePTFE (8.8 N, p = 0.02). Peel strength of mesh from the abdominal wall was less for ePTFE (1.3 N/cm of mesh width) than for PCO (2.8 N/cm, p = 0.001) or PPM (2.1 N/cm, p = 0.05). ePTFE area (94.4 cm(2)) was less than that for PCO (118.6 cm(2), p < 0.001) or PPM (140.7 cm(2), p < 0.02). CONCLUSION: PCO had fewer and less severe adhesions than ePTFE or PPM while facilitating excellent ingrowth of the adjacent parietal tissue.
BACKGROUND: The ideal mesh for laparoscopic ventral hernia repair is not yet identified. METHODS: We laparoscopically placed polypropylene (PPM), expanded polytetrafluoroethylene (ePTFE), and polyester with antiadhesive collagen layer (PCO) in eight pigs using sutures and tacks for fixation. After 28-day survival, we compared adhesion formation, fibrous ingrowth, and shrinkage among the types of mesh. RESULTS: Mean area of adhesions to PCO (8.25%) was less than that to ePTFE (57.14%, p < 0.001) or PPM (79.38%, p < 0.001). Adhesions peel strength was less for PCO (2.3 N) than for PPM (16.1 N, p < 0.001) or ePTFE (8.8 N, p = 0.02). Peel strength of mesh from the abdominal wall was less for ePTFE (1.3 N/cm of mesh width) than for PCO (2.8 N/cm, p = 0.001) or PPM (2.1 N/cm, p = 0.05). ePTFE area (94.4 cm(2)) was less than that for PCO (118.6 cm(2), p < 0.001) or PPM (140.7 cm(2), p < 0.02). CONCLUSION: PCO had fewer and less severe adhesions than ePTFE or PPM while facilitating excellent ingrowth of the adjacent parietal tissue.
Authors: R W Luijendijk; W C Hop; M P van den Tol; D C de Lange; M M Braaksma; J N IJzermans; R U Boelhouwer; B C de Vries; M K Salu; J C Wereldsma; C M Bruijninckx; J Jeekel Journal: N Engl J Med Date: 2000-08-10 Impact factor: 91.245
Authors: H Ellis; B J Moran; J N Thompson; M C Parker; M S Wilson; D Menzies; A McGuire; A M Lower; R J Hawthorn; F O'Brien; S Buchan; A M Crowe Journal: Lancet Date: 1999-05-01 Impact factor: 79.321
Authors: Brent D Matthews; Broc L Pratt; Harrison S Pollinger; Charles L Backus; Kent W Kercher; R F Sing; B Todd Heniford Journal: J Surg Res Date: 2003-10 Impact factor: 2.192
Authors: T M Saettele; S L Bachman; C R Costello; S A Grant; D S Cleveland; T S Loy; D G Kolder; B J Ramshaw Journal: Hernia Date: 2007-02-06 Impact factor: 4.739
Authors: Ernst J P Schoenmaeckers; Steef B A van der Valk; Huib W van den Hout; Johan F T J Raymakers; Srdjan Rakic Journal: Surg Endosc Date: 2009-05-15 Impact factor: 4.584