AIMS: Catheter ablation of atrial fibrillation (AF) is centred on pulmonary vein (PV) ablation with or without additional atrial substrate modification. These procedures may be prolonged with significant fluoroscopy exposure. This study evaluates a new non-fluoroscopic navigation system during ablation of AF. METHODS AND RESULTS:Seventy-two patients undergoing catheter ablation of symptomatic drug refractory AF were prospectively randomized to ablation with (n=35; study group) or without (n=37; control group) non-fluoroscopic navigation. PV isolation was performed in all patients. In patients with persistent or inducible sustained AF after PV isolation linear ablation was performed by joining the superior PVs. PV isolation was achieved in all patients; fluoroscopy (15.4+/-3.4 vs. 21.3+/-6.4 min; P<0.001) and procedural (52+/-12 vs. 61+/-17 min; P=0.02) durations were significantly reduced in the study group. Linear block was achieved in 37 of the 39 patients; with a significant reduction in fluoroscopy (5.6+/-2.2 vs. 9.9+/-4.8 min; P=0.003) and procedural (14.7+/-5.5 vs. 26.6+/-16.9 min; P=0.007) durations in the study group. After a follow-up of 6.9+/-2.9 months (range 3-10), 26 (74%) patients in the non-fluoroscopic navigation group and 29 (78%) patients in the control group were arrhythmia-free after the first procedure. CONCLUSION: This prospectively randomized study demonstrates significant reduction of fluoroscopy exposure and procedural duration using supplementary non-fluoroscopic imaging system for AF ablation.
RCT Entities:
AIMS: Catheter ablation of atrial fibrillation (AF) is centred on pulmonary vein (PV) ablation with or without additional atrial substrate modification. These procedures may be prolonged with significant fluoroscopy exposure. This study evaluates a new non-fluoroscopic navigation system during ablation of AF. METHODS AND RESULTS: Seventy-two patients undergoing catheter ablation of symptomatic drug refractory AF were prospectively randomized to ablation with (n=35; study group) or without (n=37; control group) non-fluoroscopic navigation. PV isolation was performed in all patients. In patients with persistent or inducible sustained AF after PV isolation linear ablation was performed by joining the superior PVs. PV isolation was achieved in all patients; fluoroscopy (15.4+/-3.4 vs. 21.3+/-6.4 min; P<0.001) and procedural (52+/-12 vs. 61+/-17 min; P=0.02) durations were significantly reduced in the study group. Linear block was achieved in 37 of the 39 patients; with a significant reduction in fluoroscopy (5.6+/-2.2 vs. 9.9+/-4.8 min; P=0.003) and procedural (14.7+/-5.5 vs. 26.6+/-16.9 min; P=0.007) durations in the study group. After a follow-up of 6.9+/-2.9 months (range 3-10), 26 (74%) patients in the non-fluoroscopic navigation group and 29 (78%) patients in the control group were arrhythmia-free after the first procedure. CONCLUSION: This prospectively randomized study demonstrates significant reduction of fluoroscopy exposure and procedural duration using supplementary non-fluoroscopic imaging system for AF ablation.
Authors: Nikola Pavlović; Tobias Reichlin; Michael Kühne; Sven Knecht; Stefan Osswald; Christian Sticherling Journal: J Interv Card Electrophysiol Date: 2014-11-15 Impact factor: 1.900
Authors: David J Sahn; Douglas N Stephens; Jonathan M Cannata; K Shung; Omer Oralkan; Amin Nikoozadeh; B T Pierre Khuri-Yakub; Hien Nguyen; Peter Chen; Aaron M Dentinger; Douglas Wildes; Kai E Thomenius; Aman Mahajan; Kalyanam Shivkumar; Matthew O'Donnell Journal: Conf Proc IEEE Eng Med Biol Soc Date: 2009
Authors: D N Stephens; J Cannata; Ruibin Liu; Jian Zhong Zhao; K K Shung; Hien Nguyen; R Chia; A Dentinger; D Wildes; K E Thomenius; A Mahajan; K Shivkumar; Kang Kim; M O'Donnell; A Nikoozadeh; O Oralkan; P T Khuri-Yakub; D J Sahn Journal: IEEE Trans Ultrason Ferroelectr Freq Control Date: 2008-07 Impact factor: 2.725