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Literature DB >> 15738433

Pharmacogenetics, ethical issues: review of the Nuffield Council on Bioethics Report.

Abstract

In September this year the Nuffield Council on Bioethics held a meeting to disclose and discuss the main findings of their newly published report on the ethical issues associated with developments in pharmacogenetics research. The basics of pharmacogenetics science is briefly outlined, and then the extent to which the report was successful in addressing (or at least highlighting) the attendant social, ethical, and policy implications of pharmacogenetics research is evaluated.

Keywords: Biomedical and Behavioral Research; Genetics and Reproduction; Nuffield Council on Bioethics

Mesh：

Year: 2005 PMID： 15738433 PMCID： PMC1734105 DOI： 10.1136/jme.2004.007229

Source DB: PubMed Journal: J Med Ethics ISSN： 0306-6800 Impact factor: 2.903

23 in total

Review 1. Pharmacogenetics and future drug development and delivery.

Authors: A D Roses
Journal: Lancet Date: 2000-04-15 Impact factor: 79.321

Review 2. Emerging ethical issues in pharmacogenomics: from research to clinical practice.

Authors: Carol L Freund; Benjamin S Wilfond
Journal: Am J Pharmacogenomics Date: 2002

3. Dyspepsia management in the millennium: to test and treat or not?

Authors: B C Delaney
Journal: Gut Date: 2003-01 Impact factor: 23.059

4. Principles, organization, and operation of a DNA bank for clinical trials: a Department of Veterans Affairs cooperative study.

Authors: Philip W Lavori; Heidi Krause-Steinrauf; Mary Brophy; Joel Buxbaum; Jennifer Cockroft; David R Cox; Louis Fiore; Henry T Greely; Harry Greenberg; Edward W Holmes; Lorene M Nelson; Jeremy Sugarman
Journal: Control Clin Trials Date: 2002-06

Review 5. Ethical, social and legal implications of pharmacogenomics: a critical review.

Authors: Claus Moldrup
Journal: Community Genet Date: 2001

6. Pharmacogenetics: ethical issues and policy options.

Authors: Allen Buchanan; Andrea Califano; Jeffrey Kahn; Elizabeth McPherson; John Robertson; Baruch Brody
Journal: Kennedy Inst Ethics J Date: 2002-03

Review 7. Adverse drug reactions.

Authors: M Pirmohamed; A M Breckenridge; N R Kitteringham; B K Park
Journal: BMJ Date: 1998-04-25

8. Comments on gender differences in pharmacokinetics and pharmacodynamics.

Authors: K Dawkins; M V Rudorfer; W Z Potter
Journal: Am J Psychiatry Date: 1993-04 Impact factor: 18.112

9. The economics of gene therapy and of pharmacogenetics.

Authors: Patricia Danzon; Adrian Towse
Journal: Value Health Date: 2002 Jan-Feb Impact factor: 5.725

10. Use of pharmacogenetics and clinical factors to predict the maintenance dose of warfarin.

Authors: Brian F Gage; Charles Eby; Paul E Milligan; Gerald A Banet; Jill R Duncan; Howard L McLeod
Journal: Thromb Haemost Date: 2004-01 Impact factor: 5.249

7 in total

1. Cost-effectiveness of pharmacogenetic testing to tailor smoking-cessation treatment.

Authors: D F Heitjan; D A Asch; Riju Ray; Margaret Rukstalis; Freda Patterson; C Lerman
Journal: Pharmacogenomics J Date: 2008-03-18 Impact factor: 3.550

2. Communication of pharmacogenetic research results to HIV-infected treated patients: standpoints of professionals and patients.

Authors: Grégoire Moutel; Nathalie Duchange; François Raffi; Lama I Sharara; Ioannis Théodorou; Violaine Noël; Sandrine de Montgolfier; Ingrid Callies; François Bricaire; Christian Hervé; Catherine Leport
Journal: Eur J Hum Genet Date: 2005-09 Impact factor: 4.246