Literature DB >> 15731093

GeneChip analyses of global transcriptional responses of murine macrophages to the lethal toxin of Bacillus anthracis.

Jason E Comer1, Cristi L Galindo, Ashok K Chopra, Johnny W Peterson.   

Abstract

We performed GeneChip analyses on RNA from Bacillus anthracis lethal toxin (LeTx)-treated RAW 264.7 murine macrophages to investigate global effects of anthrax toxin on host cell gene expression. Stringent analysis of data revealed that the expression of several mitogen-activated protein kinase kinase-regulatory genes was affected within 1.5 h post-exposure to LeTx. By 3.0 h, the expression of 103 genes was altered, including those involved in intracellular signaling, energy production, and protein metabolism.

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Year:  2005        PMID： 15731093      PMCID： PMC1064962          DOI： 10.1128/IAI.73.3.1879-1885.2005

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  66 in total

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Journal:  Immunity       Date:  1999-10       Impact factor: 31.745

2.  Comparative analysis of CD137 and LPS effects on monocyte activation, survival, and proliferation.

Authors:  J Langstein; F M Becke; L Söllner; G Krause; G Brockhoff; M Kreutz; R Andreesen; H Schwarz
Journal:  Biochem Biophys Res Commun       Date:  2000-06-24       Impact factor: 3.575

3.  Decreased glycogen synthase kinase 3-beta levels and related physiological changes in Bacillus anthracis lethal toxin-treated macrophages.

Authors:  Amy E Tucker; Isabelle I Salles; Daniel E Voth; William Ortiz-Leduc; Han Wang; Igor Dozmorov; Michael Centola; Jimmy D Ballard
Journal:  Cell Microbiol       Date:  2003-08       Impact factor: 3.715

4.  Local abnormalities in coagulation and fibrinolytic pathways predispose to alveolar fibrin deposition in the adult respiratory distress syndrome.

Authors:  S Idell; K K James; E G Levin; B S Schwartz; N Manchanda; R J Maunder; T R Martin; J McLarty; D S Fair
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5.  Susceptibility of mitogen-activated protein kinase kinase family members to proteolysis by anthrax lethal factor.

Authors:  G Vitale; L Bernardi; G Napolitani; M Mock; C Montecucco
Journal:  Biochem J       Date:  2000-12-15       Impact factor: 3.857

6.  CD137 induces proliferation and endomitosis in monocytes.

Authors:  J Langstein; J Michel; H Schwarz
Journal:  Blood       Date:  1999-11-01       Impact factor: 22.113

7.  Internalization and processing of Bacillus anthracis lethal toxin by toxin-sensitive and -resistant cells.

Authors:  Y Singh; S H Leppla; R Bhatnagar; A M Friedlander
Journal:  J Biol Chem       Date:  1989-07-05       Impact factor: 5.157

8.  Role of toxin functional domains in anthrax pathogenesis.

Authors:  F Brossier; M Weber-Levy; M Mock; J C Sirard
Journal:  Infect Immun       Date:  2000-04       Impact factor: 3.441

9.  Structural characterization of the human fast skeletal muscle troponin I gene (TNNI2).

Authors:  A J Mullen; P J Barton
Journal:  Gene       Date:  2000-01-25       Impact factor: 3.688

10.  Aspergillus fumigatus evades immune recognition during germination through loss of toll-like receptor-4-mediated signal transduction.

Authors:  Mihai G Netea; Adilia Warris; Jos W M Van der Meer; Matthew J Fenton; Trees J G Verver-Janssen; Liesbeth E H Jacobs; Tonje Andresen; Paul E Verweij; Bart Jan Kullberg
Journal:  J Infect Dis       Date:  2003-07-01       Impact factor: 5.226
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  13 in total

1.  The case for developing consensus standards for research in microbial pathogenesis: Bacillus anthracis toxins as an example.

Authors:  Molly A Hughes; Drusilla L Burns; Stephen J Juris; Wei-Jen Tang; Kristin H Clement; Linda J Eaton; Cassandra D Kelly-Cirino; Marian L McKee; Bradford S Powell; Brian L Bishop; Thomas L Rudge; Nancy Shine; Anita Verma; Melissa Swope Willis; Stephen A Morse
Journal:  Infect Immun       Date:  2009-08-03       Impact factor: 3.441

2.  Systems analysis of the transcriptional response of human ileocecal epithelial cells to Clostridium difficile toxins and effects on cell cycle control.

Authors:  Kevin M D'Auria; Gina M Donato; Mary C Gray; Glynis L Kolling; Cirle A Warren; Lauren M Cave; Michael D Solga; Joanne A Lannigan; Jason A Papin; Erik L Hewlett
Journal:  BMC Syst Biol       Date:  2012-01-06

3.  Role of anthrax toxins in dissemination, disease progression, and induction of protective adaptive immunity in the mouse aerosol challenge model.

Authors:  Crystal L Loving; Taruna Khurana; Manuel Osorio; Gloria M Lee; Vanessa K Kelly; Scott Stibitz; Tod J Merkel
Journal:  Infect Immun       Date:  2008-10-27       Impact factor: 3.441

4.  The role of NF-kappaB and H3K27me3 demethylase, Jmjd3, on the anthrax lethal toxin tolerance of RAW 264.7 cells.

Authors:  Nando Dulal Das; Kyoung Hwa Jung; Young Gyu Chai
Journal:  PLoS One       Date:  2010-03-29       Impact factor: 3.240

5.  Bacillus anthracis lethal toxin represses MMTV promoter activity through transcription factors.

Authors:  Zhigang Kang; Jeanette I Webster Marketon; Antoinette Johnson; Esther M Sternberg
Journal:  J Mol Biol       Date:  2009-04-21       Impact factor: 5.469

6.  Transcriptional profiling of murine organ genes in response to infection with Bacillus anthracis Ames spores.

Authors:  Scott T Moen; Linsey A Yeager; William S Lawrence; Cindy Ponce; Cristi L Galindo; Harold R Garner; Wallace B Baze; Giovanni Suarez; Johnny W Peterson; Ashok K Chopra
Journal:  Microb Pathog       Date:  2007-10-23       Impact factor: 3.738

Review 7.  Cellular and systemic effects of anthrax lethal toxin and edema toxin.

Authors:  Mahtab Moayeri; Stephen H Leppla
Journal:  Mol Aspects Med       Date:  2009-07-26

8.  Efficacy of a vaccine based on protective antigen and killed spores against experimental inhalational anthrax.

Authors:  Yves P Gauthier; Jean-Nicolas Tournier; Jean-Charles Paucod; Jean-Philippe Corre; Michèle Mock; Pierre L Goossens; Dominique R Vidal
Journal:  Infect Immun       Date:  2008-12-29       Impact factor: 3.441

9.  Anthrax lethal toxin induced lysosomal membrane permeabilization and cytosolic cathepsin release is Nlrp1b/Nalp1b-dependent.

Authors:  Kathleen M Averette; Matthew R Pratt; Yanan Yang; Sara Bassilian; Julian P Whitelegge; Joseph A Loo; Tom W Muir; Kenneth A Bradley
Journal:  PLoS One       Date:  2009-11-18       Impact factor: 3.240

10.  Anthrax infection inhibits the AKT signaling involved in the E-cadherin-mediated adhesion of lung epithelial cells.

Authors:  Taissia Popova; Virginia Espina; Charles Bailey; Lance Liotta; Emanuel Petricoin; Serguei Popov
Journal:  FEMS Immunol Med Microbiol       Date:  2009-04-08
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