Literature DB >> 15728944

Molecular epidemiology and prevalence of macrolide efflux genes mef(A) and mef(E) in Streptococcus pneumoniae obtained in Canada from 1997 to 2002.

Aleksandra K Wierzbowski1, Dean Swedlo, Dave Boyd, Michael Mulvey, Kim A Nichol, Daryl J Hoban, George G Zhanel.   

Abstract

One hundred forty M phenotype Streptococcus pneumoniae isolates were evaluated by PCR-restriction fragment length polymorphism, serotyping, and pulsed-field gel electrophoresis. Molecular genotyping revealed that the predominant macrolide resistance mechanism in S. pneumoniae in Canada is mef(E) and resistance dissemination is due to both spread of the genetic element MEGA as well as clonal dissemination of penicillin- and/or macrolide-resistant strains.

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Year:  2005        PMID： 15728944      PMCID： PMC549219          DOI： 10.1128/AAC.49.3.1257-1261.2005

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  15 in total

1.  Phenotypes and genotypes of erythromycin-resistant pneumococci in Italy.

Authors:  Maria Pia Montanari; Marina Mingoia; Ileana Cochetti; Pietro Emanuele Varaldo
Journal:  J Clin Microbiol       Date:  2003-01       Impact factor: 5.948

2.  Macrolide efflux genes mef(A) and mef(E) are carried by different genetic elements in Streptococcus pneumoniae.

Authors:  M Del Grosso; F Iannelli; C Messina; M Santagati; N Petrosillo; S Stefani; G Pozzi; A Pantosti
Journal:  J Clin Microbiol       Date:  2002-03       Impact factor: 5.948

3.  Patterns of macrolide resistance determinants among community-acquired Streptococcus pneumoniae isolates over a 5-year period of decreased macrolide susceptibility rates.

Authors:  P Oster; A Zanchi; S Cresti; M Lattanzi; F Montagnani; C Cellesi; G M Rossolini
Journal:  Antimicrob Agents Chemother       Date:  1999-10       Impact factor: 5.191

4.  Macrolide-resistant Streptococcus pneumoniae in Canada during 1998-1999: prevalence of mef(A) and erm(B) and susceptibilities to ketolides.

Authors:  D J Hoban; A K Wierzbowski; K Nichol; G G Zhanel
Journal:  Antimicrob Agents Chemother       Date:  2001-07       Impact factor: 5.191

5.  Characterization of a genetic element carrying the macrolide efflux gene mef(A) in Streptococcus pneumoniae.

Authors:  M Santagati; F Iannelli; M R Oggioni; S Stefani; G Pozzi
Journal:  Antimicrob Agents Chemother       Date:  2000-09       Impact factor: 5.191

6.  Detection of erythromycin-resistant determinants by PCR.

Authors:  J Sutcliffe; T Grebe; A Tait-Kamradt; L Wondrack
Journal:  Antimicrob Agents Chemother       Date:  1996-11       Impact factor: 5.191

7.  Molecular epidemiology of erythromycin resistance in Streptococcus pneumoniae isolates from blood and noninvasive sites.

Authors:  Maria Rosario Amezaga; Philip E Carter; Phillip Cash; Hamish McKenzie
Journal:  J Clin Microbiol       Date:  2002-09       Impact factor: 5.948

8.  Molecular epidemiology of penicillin-susceptible non-beta-lactam-resistant Streptococcus pneumoniae isolates from Greek children.

Authors:  D Bogaert; P W M Hermans; I N Grivea; G S Katopodis; T J Mitchell; M Sluijter; R De Groot; N G Beratis; G A Syrogiannopoulos
Journal:  J Clin Microbiol       Date:  2003-12       Impact factor: 5.948

9.  Molecular epidemiology of penicillin-resistant and ciprofloxacin-resistant Streptococcus pneumoniae in Canada.

Authors:  Kimberly A Nichol; George G Zhanel; Daryl J Hoban
Journal:  Antimicrob Agents Chemother       Date:  2003-02       Impact factor: 5.191

10.  Emergence of macrolide resistance in throat culture isolates of group a streptococci in Ontario, Canada, in 2001.

Authors:  Kevin C Katz; Allison J McGeer; Carla L Duncan; Aisha Ashi-Sulaiman; Barbara M Willey; Alicia Sarabia; Jacquie McCann; Sylvia Pong-Porter; Yana Rzayev; Joyce S de Azavedo; Donald E Low
Journal:  Antimicrob Agents Chemother       Date:  2003-07       Impact factor: 5.191
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  6 in total

1.  Increase of the M phenotype among erythromycin-resistant Streptococcus pneumoniae isolates from Spain related to the serotype 14 variant of the Spain9V-3 clone.

Authors:  C Ardanuy; A Fenoll; S Berrón; L Calatayud; J Liñares
Journal:  Antimicrob Agents Chemother       Date:  2006-09       Impact factor: 5.191

Review 2.  Efflux-mediated drug resistance in bacteria: an update.

Authors:  Xian-Zhi Li; Hiroshi Nikaido
Journal:  Drugs       Date:  2009-08-20       Impact factor: 9.546

3.  Molecular characterization of pneumococci with efflux-mediated erythromycin resistance and identification of a novel mef gene subclass, mef(I).

Authors:  Ileana Cochetti; Manuela Vecchi; Marina Mingoia; Emily Tili; Maria R Catania; Aldo Manzin; Pietro E Varaldo; Maria Pia Montanari
Journal:  Antimicrob Agents Chemother       Date:  2005-12       Impact factor: 5.191

4.  Expression of the mef(E) gene encoding the macrolide efflux pump protein increases in Streptococcus pneumoniae with increasing resistance to macrolides.

Authors:  Aleksandra K Wierzbowski; Dave Boyd; Michael Mulvey; Daryl J Hoban; George G Zhanel
Journal:  Antimicrob Agents Chemother       Date:  2005-11       Impact factor: 5.191

5.  The mef(E)-carrying genetic element (mega) of Streptococcus pneumoniae: insertion sites and association with other genetic elements.

Authors:  Maria Del Grosso; Romina Camilli; Francesco Iannelli; Gianni Pozzi; Annalisa Pantosti
Journal:  Antimicrob Agents Chemother       Date:  2006-10       Impact factor: 5.191

Review 6.  Macrolide Resistance in Streptococcus pneumoniae.

Authors:  Max R Schroeder; David S Stephens
Journal:  Front Cell Infect Microbiol       Date:  2016-09-21       Impact factor: 5.293
  6 in total

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