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Literature DB >> 12543698

Molecular epidemiology of penicillin-resistant and ciprofloxacin-resistant Streptococcus pneumoniae in Canada.

Kimberly A Nichol¹, George G Zhanel, Daryl J Hoban.

Abstract

Eighty-nine penicillin- and ciprofloxacin-resistant Streptococcus pneumoniae isolates were evaluated by serotyping and pulsed-field gel electrophoresis. Although penicillin-resistant isolates demonstrated considerable homogeneity, resistance to ciprofloxacin did not correlate with a reduction in genotypic variability. These results suggest that, unlike that of penicillin resistance, the spread of S. pneumoniae ciprofloxacin resistance in Canada is currently not attributable to clonal dissemination.

Entities: Chemical Species

Mesh：

Substances：
Ciprofloxacin

Year: 2003 PMID： 12543698 PMCID： PMC151757 DOI： 10.1128/AAC.47.2.804-808.2003

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

12 in total

1. Streptococcus pneumoniae isolates with reduced susceptibility to ciprofloxacin in Spain: clonal diversity and appearance of ciprofloxacin-resistant epidemic clones.

Authors: L Alou; M Ramirez; C García-Rey; J Prieto; H de Lencastre
Journal: Antimicrob Agents Chemother Date: 2001-10 Impact factor: 5.191

2. Fluoroquinolone resistance among clinical isolates of Streptococcus pneumoniae belonging to international multiresistant clones.

Authors: Lesley McGee; Colin E Goldsmith; Keith P Klugman
Journal: J Antimicrob Chemother Date: 2002-01 Impact factor: 5.790

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Journal: Clin Infect Dis Date: 1992-07 Impact factor: 9.079

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Authors: M J Caimano; G G Hardy; J Yother
Journal: Microb Drug Resist Date: 1998 Impact factor: 3.431

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Authors: M Lovgren; J S Spika; J A Talbot
Journal: CMAJ Date: 1998-02-10 Impact factor: 8.262

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Authors: M Ip; D J Lyon; R W Yung; C Chan; A F Cheng
Journal: J Clin Microbiol Date: 1999-09 Impact factor: 5.948

Review 7. Antimicrobial resistance in Streptococcus pneumoniae: an overview.

Authors: P C Appelbaum
Journal: Clin Infect Dis Date: 1992-07 Impact factor: 9.079

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Authors: D K Chen; A McGeer; J C de Azavedo; D E Low
Journal: N Engl J Med Date: 1999-07-22 Impact factor: 91.245

9. Molecular analysis of the genetic variation among penicillin-susceptible and penicillin-resistant Streptococcus pneumoniae serotypes in Canada.

Authors: M Louie; L Louie; G Papia; J Talbot; M Lovgren; A E Simor
Journal: J Infect Dis Date: 1999-04 Impact factor: 5.226

10. Historical changes in pneumococcal serogroup distribution: implications for the era of pneumococcal conjugate vaccines.

Authors: Daniel R Feikin; Keith P Klugman
Journal: Clin Infect Dis Date: 2002-08-07 Impact factor: 9.079

10 in total

1. Nonmolecular test for detection of low-level resistance to fluoroquinolones in Streptococcus pneumoniae.

Authors: Emmanuelle Varon; Serge Houssaye; Sophie Grondin; Laurent Gutmann
Journal: Antimicrob Agents Chemother Date: 2006-02 Impact factor: 5.191

2. Genetic relatedness of levofloxacin-nonsusceptible Streptococcus pneumoniae isolates from North America.

Authors: Crystal N Johnson; William H Benjamin Jr; Stephen A Moser; Susan K Hollingshead; Xiaotian Zheng; Marilyn J Crain; Moon H Nahm; Ken B Waites
Journal: J Clin Microbiol Date: 2003-06 Impact factor: 5.948

3. Molecular epidemiology and prevalence of macrolide efflux genes mef(A) and mef(E) in Streptococcus pneumoniae obtained in Canada from 1997 to 2002.

Authors: Aleksandra K Wierzbowski; Dean Swedlo; Dave Boyd; Michael Mulvey; Kim A Nichol; Daryl J Hoban; George G Zhanel
Journal: Antimicrob Agents Chemother Date: 2005-03 Impact factor: 5.191

4. Phenotypic and molecular analysis of penicillin-nonsusceptible Streptococcus pneumoniae isolates in Poland.

Authors: Ewa Sadowy; Radoslaw Izdebski; Anna Skoczynska; Pawel Grzesiowski; Marek Gniadkowski; Waleria Hryniewicz
Journal: Antimicrob Agents Chemother Date: 2006-10-16 Impact factor: 5.191

5. Molecular analysis of pbp2b in Streptococcus pneumonia isolated from clinical and normal flora samples.

Authors: J Sadeghi; A Ahamadi; M Douraghi; M R Pourshafie; M Talebi
Journal: Curr Microbiol Date: 2014-10-02 Impact factor: 2.188

6. Stability of fluoroquinolone resistance in Streptococcus pneumoniae clinical isolates and laboratory-derived mutants.

Authors: Heather J Smith-Adam; Kimberly A Nichol; Daryl J Hoban; George G Zhanel
Journal: Antimicrob Agents Chemother Date: 2005-02 Impact factor: 5.191

7. Molecular characterization of increasing fluoroquinolone resistance in Streptococcus pneumoniae isolates in Canada, 1997 to 2005.

Authors: Heather J Adam; Kristen N Schurek; Kimberly A Nichol; Chris J Hoban; Trish J Baudry; Nancy M Laing; Daryl J Hoban; George G Zhanel
Journal: Antimicrob Agents Chemother Date: 2006-11-06 Impact factor: 5.191