Literature DB >> 15713404

Novel jadomycins: incorporation of non-natural and natural amino acids.

David L Jakeman1, Spring Farrell, Wendy Young, René J Doucet, Shannon C Timmons.   

Abstract

Electrospray ionization mass spectrometry of extracts from Streptomyces venezuelae ISP5230 cultures grown on chemically synthesized non-natural L-amino acids, D-amino acids or any of the 20 natural amino acids demonstrated incorporation of the amino acid into a jadomycin B analogue.

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Year:  2005        PMID： 15713404     DOI： 10.1016/j.bmcl.2004.12.082

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  8 in total

1.  Culture conditions improving the production of jadomycin B.

Authors:  David L Jakeman; Cathy L Graham; Wendy Young; Leo C Vining
Journal:  J Ind Microbiol Biotechnol       Date:  2006-03-28       Impact factor: 3.346

2.  Multi-oxygenase complexes of the gilvocarcin and jadomycin biosyntheses.

Authors:  Madan K Kharel; Lili Zhu; Tao Liu; Jürgen Rohr
Journal:  J Am Chem Soc       Date:  2007-03-09       Impact factor: 15.419

3.  Antimicrobial activities of jadomycin B and structurally related analogues.

Authors:  David L Jakeman; Srinivasulu Bandi; Cathy L Graham; Taryn R Reid; Jason R Wentzell; Susan E Douglas
Journal:  Antimicrob Agents Chemother       Date:  2008-12-15       Impact factor: 5.191

4.  Biosynthesis and Total Synthesis Studies on The Jadomycin Family of Natural Products.

Authors:  Ehesan U Sharif; George A O'Doherty
Journal:  European J Org Chem       Date:  2012-04

5.  Jadomycin breast cancer cytotoxicity is mediated by a copper-dependent, reactive oxygen species-inducing mechanism.

Authors:  Steven R Hall; Heather L Blundon; Matthew A Ladda; Andrew W Robertson; Camilo F Martinez-Farina; David L Jakeman; Kerry B Goralski
Journal:  Pharmacol Res Perspect       Date:  2015-03

6.  Streptomyces venezuelae ISP5230 Maintains Excretion of Jadomycin upon Disruption of the MFS Transporter JadL Located within the Natural Product Biosynthetic Gene Cluster.

Authors:  Stephanie M Forget; Jennifer McVey; Leo C Vining; David L Jakeman
Journal:  Front Microbiol       Date:  2017-03-21       Impact factor: 5.640

7.  Direct Synthesis of the Phenanthroviridone Skeleton Using a Highly Regioselective Nitroquinone Diels-Alder Reaction.

Authors:  Huangchao Yu; Ellie L Fought; Theresa L Windus; George A Kraus
Journal:  ACS Omega       Date:  2020-04-17

8.  Functional gene-guided discovery of type II polyketides from culturable actinomycetes associated with soft coral Scleronephthya sp.

Authors:  Wei Sun; Chongsheng Peng; Yunyu Zhao; Zhiyong Li
Journal:  PLoS One       Date:  2012-08-07       Impact factor: 3.240
  8 in total

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