Literature DB >> 15712316

Elucidation of the glycosylation sequence of mithramycin biosynthesis: isolation of 3A-deolivosylpremithramycin B and its conversion to premithramycin B by glycosyltransferase MtmGII.

Mohammad Nur-e-Alam1, Carmen Méndez, José A Salas, Jürgen Rohr.   

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Year:  2005        PMID： 15712316     DOI： 10.1002/cbic.200400309

Source DB:  PubMed          Journal:  Chembiochem        ISSN： 1439-4227            Impact factor:   3.164


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  12 in total

1.  Deoxysugar transfer during chromomycin A3 biosynthesis in Streptomyces griseus subsp. griseus: new derivatives with antitumor activity.

Authors:  Nuria Menéndez; Mohammad Nur-e-Alam; Carsten Fischer; Alfredo F Braña; José A Salas; Jürgen Rohr; Carmen Méndez
Journal:  Appl Environ Microbiol       Date:  2006-01       Impact factor: 4.792

2.  Premithramycinone G, an early shunt product of the mithramycin biosynthetic pathway accumulated upon inactivation of oxygenase MtmOII.

Authors:  Mohamed S Abdelfattah; Jürgen Rohr
Journal:  Angew Chem Int Ed Engl       Date:  2006-08-25       Impact factor: 15.336

3.  Crystallization and X-ray diffraction properties of Baeyer-Villiger monooxygenase MtmOIV from the mithramycin biosynthetic pathway in Streptomyces argillaceus.

Authors:  Chenchen Wang; Miranda Gibson; Jurgen Rohr; Marcos A Oliveira
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2005-10-28

4.  Structural insight into MtmC, a bifunctional ketoreductase-methyltransferase involved in the assembly of the mithramycin trisaccharide chain.

Authors:  Jhong-Min Chen; Caixia Hou; Guojun Wang; Oleg V Tsodikov; Jürgen Rohr
Journal:  Biochemistry       Date:  2015-04-07       Impact factor: 3.162

5.  Cooperation of two bifunctional enzymes in the biosynthesis and attachment of deoxysugars of the antitumor antibiotic mithramycin.

Authors:  Guojun Wang; Pallab Pahari; Madan K Kharel; Jing Chen; Haining Zhu; Steven G Van Lanen; Jürgen Rohr
Journal:  Angew Chem Int Ed Engl       Date:  2012-09-20       Impact factor: 15.336

6.  Investigating Mithramycin deoxysugar biosynthesis: enzymatic total synthesis of TDP-D-olivose.

Authors:  Guojun Wang; Madan K Kharel; Pallab Pahari; Jürgen Rohr
Journal:  Chembiochem       Date:  2011-09-29       Impact factor: 3.164

7.  Two Cooperative Glycosyltransferases Are Responsible for the Sugar Diversity of Saquayamycins Isolated from Streptomyces sp. KY 40-1.

Authors:  Shaimaa M Salem; Stevi Weidenbach; Jürgen Rohr
Journal:  ACS Chem Biol       Date:  2017-09-13       Impact factor: 5.100

8.  Mithramycin analogues generated by combinatorial biosynthesis show improved bioactivity.

Authors:  Irfan Baig; María Perez; Alfredo F Braña; Rohini Gomathinayagam; Chendil Damodaran; Jose A Salas; Carmen Méndez; Jürgen Rohr
Journal:  J Nat Prod       Date:  2008-01-15       Impact factor: 4.050

9.  Crystal structure of Baeyer-Villiger monooxygenase MtmOIV, the key enzyme of the mithramycin biosynthetic pathway .

Authors:  Miranda P Beam; Mary A Bosserman; Nicholas Noinaj; Marie Wehenkel; Jürgen Rohr
Journal:  Biochemistry       Date:  2009-06-02       Impact factor: 3.162

10.  Generation of new derivatives of the antitumor antibiotic mithramycin by altering the glycosylation pattern through combinatorial biosynthesis.

Authors:  María Pérez; Irfan Baig; Alfredo F Braña; José A Salas; Jürgen Rohr; Carmen Méndez
Journal:  Chembiochem       Date:  2008-09-22       Impact factor: 3.164
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