Literature DB >> 15686905

Synthesis and antibacterial activity of 1-[1,2,4-triazol-3-yl] and 1-[1,3,4-thiadiazol-2-yl]-3-methylthio-6,7-dihydrobenzo[c]thiophen-4(5H)ones.

Sara Tehranchian1, Tahmineh Akbarzadeh, Mohammad Reza Fazeli, Hossein Jamalifar, Abbas Shafiee.   

Abstract

A series of 1-[1,2,4-triazol-3-yl] and 1-[1,3,4-thiadiazol-2-yl]-3-methylthio-6,7-dihydrobenzo[c]thiophen-4(5H)ones were synthesized and tested to demonstrate in vitro antimicrobial activity. Some of these compounds exhibited a good activity against Staphylococcus aureus, S. epidermidis and Bacillus subtilis.

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Year:  2005        PMID： 15686905     DOI： 10.1016/j.bmcl.2004.12.039

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  12 in total

1.  The crystal structures and Hirshfeld surface analyses of four 3,5-diacetyl-2-methyl-2,3-di-hydro-1,3,4-thia-diazol-2-yl derivatives.

Authors:  M NizamMohideen; S Syed Abuthahir; V Viswanathan; D Velmurugan; M Karthik Ananth
Journal:  Acta Crystallogr E Crystallogr Commun       Date:  2019-09-10

2.  N-[4-Acetyl-5-methyl-5-(2-p-tolyl-prop-yl)-4,5-dihydro-1,3,4-thia-diazol-2-yl]acetamide.

Authors:  Mohamed Tebaa; Noureddine Mazoir; Celia M Maya; Bouhmaida Nouzha; Ahmed Benharref; Moha Berraho
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2009-01-10

3.  N-[1-(5-Acetamido-3-acetyl-2-methyl-2,3-dihydro-1,3,4-thia-diazol-2-yl)-2-phenyl-ethyl]acetamide.

Authors:  P Sakthivel; P S Joseph; P Thomas Muthiah; K Sethusankar; S Thennarasu
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2007-12-06

4.  N-[4-Acetyl-5-isobutyl-5-(2-p-tolyl-prop-yl)-4,5-dihydro-1,3,4-thia-diazol-2-yl]acetamide ethyl acetate hemisolvate.

Authors:  Mohamed Loughzail; Noureddine Mazoir; Celia M Maya; Moha Berraho; Ahmed Benharref; Nouzha Bouhmaida
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2008-12-03

Review 5.  2-Amino-1,3,4-thiadiazole as a potential scaffold for promising antimicrobial agents.

Authors:  Georgeta Serban; Oana Stanasel; Sanda Bota; Eugenia Serban
Journal:  Drug Des Devel Ther       Date:  2018-05-31       Impact factor: 4.162

6.  Synthesis and Biological Activities of Ethyl 2-(2-pyridylacetate) Derivatives Containing Thiourea, 1,2,4-triazole, Thiadiazole and Oxadiazole Moieties.

Authors:  Daniel Szulczyk; Piotr Tomaszewski; Michał Jóźwiak; Anna E Kozioł; Tadeusz Lis; David Collu; Filippo Iuliano; Marta Struga
Journal:  Molecules       Date:  2017-03-06       Impact factor: 4.411

7.  Simple and efficient synthesis of racemic 2-(tert-butoxycarbon-ylamino)-2-methyl-3-(1H-1,2,4-triazol-1-yl)propanoic acid, a new derivative of β-(1,2,4-triazol-1-yl)alanine.

Authors:  Younas Aouine; Hassane Faraj; Anouar Alami; Abdelilah El-Hallaoui; Abdelrhani Elachqar; Abdelali Kerbal
Journal:  Molecules       Date:  2011-04-19       Impact factor: 4.411

8.  Synthesis and crystal structure of novel sulfone derivatives containing 1,2,4-triazole moieties.

Authors:  Weiming Xu; Baoan Song; Pinaki Bhadury; Yang Song; Deyu Hu
Journal:  Molecules       Date:  2010-02-03       Impact factor: 4.411

9.  Synthesis, antimicrobial, and anti-inflammatory activities of novel 5-(1-adamantyl)-4-arylideneamino-3-mercapto-1,2,4-triazoles and related derivatives.

Authors:  Mohamed A Al-Omar; Ebtehal S Al-Abdullah; Ihsan A Shehata; Elsayed E Habib; Tarek M Ibrahim; Ali A El-Emam
Journal:  Molecules       Date:  2010-04-09       Impact factor: 4.411

10.  Synthesis of thiophene derivatives and their anti-microbial, antioxidant, anticorrosion and anticancer activity.

Authors:  Rashmi Shah; Prabhakar Kumar Verma
Journal:  BMC Chem       Date:  2019-04-18
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