Literature DB >> 15670789

A lipid dependence in the formation of twin ion channels.

Lo'ay Al-Momani1, Philipp Reiss, Ulrich Koert.   

Abstract

A gramicidin A derivative with a polyether linkage between both ethanolamine termini was synthesized and its ion channel properties were studied. The compound showed a duplication in the state of conductance for alkali cations in thick DOPC bilayer membranes, which is interpreted as the occurrence of twin-channels. In thinner DMPC membranes mono-channels were dominant. The influence of hydrophobic coupling on the mono channel/twin channel equilibrium is discussed.

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Year:  2005        PMID： 15670789     DOI： 10.1016/j.bbrc.2004.12.170

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  6 in total

1.  Quantitative modeling of membrane deformations by multihelical membrane proteins: application to G-protein coupled receptors.

Authors:  Sayan Mondal; George Khelashvili; Jufang Shan; Olaf S Andersen; Harel Weinstein
Journal:  Biophys J       Date:  2011-11-01       Impact factor: 4.033

2.  Peptide-induced membrane elastic deformations decelerate gramicidin dimer-monomer equilibration.

Authors:  Oleg V Kondrashov; Tatyana I Rokitskaya; Oleg V Batishchev; Elena A Kotova; Yuri N Antonenko; Sergey A Akimov
Journal:  Biophys J       Date:  2021-10-27       Impact factor: 4.033

3.  Membrane Elastic Deformations Modulate Gramicidin A Transbilayer Dimerization and Lateral Clustering.

Authors:  Oleg V Kondrashov; Timur R Galimzyanov; Konstantin V Pavlov; Elena A Kotova; Yuri N Antonenko; Sergey A Akimov
Journal:  Biophys J       Date:  2018-07-11       Impact factor: 4.033

4.  Membrane-Mediated Lateral Interactions Regulate the Lifetime of Gramicidin Channels.

Authors:  Oleg V Kondrashov; Timur R Galimzyanov; Rodion J Molotkovsky; Oleg V Batishchev; Sergey A Akimov
Journal:  Membranes (Basel)       Date:  2020-11-25

5.  Regulation of Antimicrobial Peptide Activity via Tuning Deformation Fields by Membrane-Deforming Inclusions.

Authors:  Oleg V Kondrashov; Sergey A Akimov
Journal:  Int J Mol Sci       Date:  2021-12-28       Impact factor: 5.923

6.  Electrostatically induced recruitment of membrane peptides into clusters requires ligand binding at both interfaces.

Authors:  Yuri N Antonenko; Andreas Horner; Peter Pohl
Journal:  PLoS One       Date:  2012-12-21       Impact factor: 3.240
  6 in total

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