| Literature DB >> 15666539 |
Habsah Mohamad1, Faridah Abas, Dharma Permana, Nordin H Lajis, Abdul Manaf Ali, Mohd Aspollah Sukari, Taufiq Y Y Hin, Hiroe Kikuzaki, Nobuji Nakatani.
Abstract
The methanol extract of the dried ripe fruits of Alpinia rafflesiana was investigated for its DPPH free radical scavenger constituents. 2',3',4',6'-Tetrahydroxychalcone (7), which has never been isolated from natural sources was found to be most active as a DPPH free radical scavenger with the IC50 value of 55 microM. Other known compounds isolated from this species include 5,6-dehydrokawain (1), flavokawin B (2). 1,7-diphenyl-5-hydroxy-6-hepten-3-one (3), (-)-pinocembrin (4), cardamonin (5) and (-)-pinostrobin (6). The DPPH free radical scavenger compounds were detected using TLC autographic analysis. The percentage inhibition of DPPH free radical scavenging activity was measured on isolates (5-7) using colorimetric analysis.Entities:
Mesh:
Substances:
Year: 2004 PMID: 15666539 DOI: 10.1515/znc-2004-11-1208
Source DB: PubMed Journal: Z Naturforsch C J Biosci ISSN: 0341-0382