Literature DB >> 15666539

DPPH free radical scavenger components from the fruits of Alpinia rafflesiana Wall. ex. Bak. (Zingiberaceae).

Habsah Mohamad1, Faridah Abas, Dharma Permana, Nordin H Lajis, Abdul Manaf Ali, Mohd Aspollah Sukari, Taufiq Y Y Hin, Hiroe Kikuzaki, Nobuji Nakatani.   

Abstract

The methanol extract of the dried ripe fruits of Alpinia rafflesiana was investigated for its DPPH free radical scavenger constituents. 2',3',4',6'-Tetrahydroxychalcone (7), which has never been isolated from natural sources was found to be most active as a DPPH free radical scavenger with the IC50 value of 55 microM. Other known compounds isolated from this species include 5,6-dehydrokawain (1), flavokawin B (2). 1,7-diphenyl-5-hydroxy-6-hepten-3-one (3), (-)-pinocembrin (4), cardamonin (5) and (-)-pinostrobin (6). The DPPH free radical scavenger compounds were detected using TLC autographic analysis. The percentage inhibition of DPPH free radical scavenging activity was measured on isolates (5-7) using colorimetric analysis.

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Year:  2004        PMID: 15666539     DOI: 10.1515/znc-2004-11-1208

Source DB:  PubMed          Journal:  Z Naturforsch C J Biosci        ISSN: 0341-0382


  9 in total

1.  Cytotoxic, radical scavenging and antimicrobial activities of sesquiterpenoids from the Tahitian liverwort Mastigophora diclados (Brid.) Nees (Mastigophoraceae).

Authors:  Ismiarni Komala; Takuya Ito; Fumihiro Nagashima; Yasuyuki Yagi; Yoshinori Asakawa
Journal:  J Nat Med       Date:  2010-05-12       Impact factor: 2.343

Review 2.  The role of chalcones in suppression of NF-κB-mediated inflammation and cancer.

Authors:  Vivek R Yadav; Sahdeo Prasad; Bokyung Sung; Bharat B Aggarwal
Journal:  Int Immunopharmacol       Date:  2010-12-22       Impact factor: 4.932

3.  Theoretical study on the antioxidant properties of 2'-hydroxychalcones: H-atom vs. electron transfer mechanism.

Authors:  Yunsheng Xue; Youguang Zheng; Ling Zhang; Wenya Wu; Ding Yu; Yi Liu
Journal:  J Mol Model       Date:  2013-06-26       Impact factor: 1.810

4.  Antioxidant and anti-acetylcholinesterase activities of extracts and secondary metabolites from Acacia cyanophylla.

Authors:  Lotfi Ghribia; Hatem Ghouilaa; Amel Omrib; Malek Besbesb; Hichem Ben Janneta
Journal:  Asian Pac J Trop Biomed       Date:  2014-05

5.  An overview on cardamonin.

Authors:  Luís Moreira Gonçalves; Inês Maria Valente; José António Rodrigues
Journal:  J Med Food       Date:  2014-01-16       Impact factor: 2.786

6.  Antimicrobial, Antioxidant, and Cytotoxic Activities of Ocimum forskolei and Teucrium yemense (Lamiaceae) Essential Oils.

Authors:  Nasser A Awadh Ali; Bhuwan K Chhetri; Noura S Dosoky; Khola Shari; Ahmed J A Al-Fahad; Ludger Wessjohann; William N Setzer
Journal:  Medicines (Basel)       Date:  2017-04-01

7.  Phytochemical and cytotoxic investigations of Alpinia mutica rhizomes.

Authors:  Sri Nurestri Abdul Malek; Chung Weng Phang; Halijah Ibrahim; Abdul Wahab Norhanom; Kae Shin Sim
Journal:  Molecules       Date:  2011-01-14       Impact factor: 4.411

8.  Anti-tumour promoting activity and antioxidant properties of girinimbine isolated from the stem bark of Murraya koenigii S.

Authors:  Yih Yih Kok; Lim Yang Mooi; Kartini Ahmad; Mohd Aspollah Sukari; Nashriyah Mat; Mawardi Rahmani; Abdul Manaf Ali
Journal:  Molecules       Date:  2012-04-20       Impact factor: 4.411

Review 9.  Pinocembrin: a novel natural compound with versatile pharmacological and biological activities.

Authors:  Azhar Rasul; Faya Martin Millimouno; Wafa Ali Eltayb; Muhammad Ali; Jiang Li; Xiaomeng Li
Journal:  Biomed Res Int       Date:  2013-08-05       Impact factor: 3.411

  9 in total

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