Literature DB >> 15665089

Microengineered hydromechanical cochlear model.

Robert D White1, Karl Grosh.   

Abstract

Micromachined fluid-filled variable impedance waveguides intended to mimic the mechanics of the passive mammalian cochlea have been fabricated and experimentally examined. The structures were microfabricated with dimensions similar to those of the biological system. Experimental tests demonstrate acoustically excited traveling fluid-structure waves with phase accumulations between 1.5 and 3 pi radians at the location of maximum response. The resulting measured frequency-position mapping function, with similarities to that observed in the cochlea, is presented. Results for both isotropic and orthotropic membranes are reported, demonstrating that the achieved orthotropy ratio of 8:1 in tension is insufficient to produce the sharp filtering observed in animal experiments and many computational models that use higher ratios. It is also shown experimentally that high viscosity fluids must be used to provide sufficient damping to avoid the formation of a nonphysiological standing wave pattern. A mathematical model incorporating a thin-layer viscous, compressible fluid approximation coupled to an orthotropic membrane model is validated against experimental results. The work presented herein is motivated by the possibility of producing microfabricated cochlear-like filters, thus the structure is designed for production in a scalable microfabrication process.

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Year:  2005        PMID: 15665089      PMCID: PMC547842          DOI: 10.1073/pnas.0407446102

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  12 in total

1.  Three-dimensional numerical modeling for global cochlear dynamics.

Authors:  A A Parthasarathi; K Grosh; A L Nuttall
Journal:  J Acoust Soc Am       Date:  2000-01       Impact factor: 1.840

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Journal:  Physiol Rev       Date:  2001-07       Impact factor: 37.312

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Authors:  C R Steele; L A Taber
Journal:  J Acoust Soc Am       Date:  1979-04       Impact factor: 1.840

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Journal:  Nature       Date:  1970-03-28       Impact factor: 49.962

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Authors:  G Zhou; L Bintz; D Z Anderson; K E Bright
Journal:  J Acoust Soc Am       Date:  1993-03       Impact factor: 1.840

6.  Finite element micromechanical modeling of the cochlea in three dimensions.

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Journal:  J Acoust Soc Am       Date:  1996-01       Impact factor: 1.840

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Authors:  T P Lechner
Journal:  Hear Res       Date:  1993-04       Impact factor: 3.208

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Journal:  J Acoust Soc Am       Date:  1985-05       Impact factor: 1.840

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Authors:  R S Chadwick; M E Fourney; P Neiswander
Journal:  Hear Res       Date:  1980-06       Impact factor: 3.208

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  18 in total

1.  Piezoelectric materials mimic the function of the cochlear sensory epithelium.

Authors:  Takatoshi Inaoka; Hirofumi Shintaku; Takayuki Nakagawa; Satoyuki Kawano; Hideaki Ogita; Tatsunori Sakamoto; Shinji Hamanishi; Hiroshi Wada; Juichi Ito
Journal:  Proc Natl Acad Sci U S A       Date:  2011-10-24       Impact factor: 11.205

2.  Three Dimensional Viscous Finite Element Formulation For Acoustic Fluid Structure Interaction.

Authors:  Lei Cheng; Robert D White; Karl Grosh
Journal:  Comput Methods Appl Mech Eng       Date:  2008-09-15       Impact factor: 6.756

3.  Acoustically detectable cellular-level lung injury induced by fluid mechanical stresses in microfluidic airway systems.

Authors:  Dongeun Huh; Hideki Fujioka; Yi-Chung Tung; Nobuyuki Futai; Robert Paine; James B Grotberg; Shuichi Takayama
Journal:  Proc Natl Acad Sci U S A       Date:  2007-11-15       Impact factor: 11.205

Review 4.  Instrumentation for studies of cochlear mechanics: from von Békésy forward.

Authors:  Alfred L Nuttall; Anders Fridberger
Journal:  Hear Res       Date:  2012-09-10       Impact factor: 3.208

5.  The cochlea as a smart structure.

Authors:  Stephen J Elliott; Christopher A Shera
Journal:  Smart Mater Struct       Date:  2012-06       Impact factor: 3.585

Review 6.  Modelling cochlear mechanics.

Authors:  Guangjian Ni; Stephen J Elliott; Mohammad Ayat; Paul D Teal
Journal:  Biomed Res Int       Date:  2014-07-23       Impact factor: 3.411

Review 7.  Analytical and numerical modeling of the hearing system: Advances towards the assessment of hearing damage.

Authors:  Annalisa De Paolis; Marom Bikson; Jeremy T Nelson; J Alexander de Ru; Mark Packer; Luis Cardoso
Journal:  Hear Res       Date:  2017-02-02       Impact factor: 3.208

8.  Cochlear perfusion with a viscous fluid.

Authors:  Yi Wang; Elizabeth S Olson
Journal:  Hear Res       Date:  2016-05-21       Impact factor: 3.208

9.  A microelectromechanical system artificial basilar membrane based on a piezoelectric cantilever array and its characterization using an animal model.

Authors:  Jongmoon Jang; JangWoo Lee; Seongyong Woo; David J Sly; Luke J Campbell; Jin-Ho Cho; Stephen J O'Leary; Min-Hyun Park; Sungmin Han; Ji-Wong Choi; Jeong Hun Jang; Hongsoo Choi
Journal:  Sci Rep       Date:  2015-07-31       Impact factor: 4.379

10.  Mechanical and Electrical Characterization of Piezoelectric Artificial Cochlear Device and Biocompatible Packaging.

Authors:  Youngdo Jung; Jun-Hyuk Kwak; Hanmi Kang; Wan Doo Kim; Shin Hur
Journal:  Sensors (Basel)       Date:  2015-07-31       Impact factor: 3.576

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