Measured pulmonary oxygen consumption: difference between systemic oxygen uptake measured by the reverse Fick method and indirect calorimetry in cardiac surgery.

Measurement of oxygen uptake by indirect calorimetry was compared with the reverse Fick method in a series of patients undergoing cardiac surgery. Oxygen uptake measurements for indirect calorimetry were made using a calibrated measurement system utilizing the Haldane transformation in a simple semiclosed breathing system based upon a modified Bain circuit. Pulmonary blood flow for the reverse Fick method was measured using bolus thermodilution. The results were (mean [standard deviation]): indirect calorimetry 167[26] ml.min(-1), and reverse Fick 148[27] ml.min(-1). Indirect calorimetry overestimated the reverse Fick value by 11.3% (p < 0.001). These results are consistent with the findings of previous studies in similar patient groups and are explained by lung tissue oxygen consumption.