Literature DB >> 15619961

Implementing large-scale ENU mutagenesis screens in North America.

Amander T Clark1, Daniel Goldowitz, Joseph S Takahashi, Martha Hotz Vitaterna, Sandra M Siepka, Luanne L Peters, Wayne N Frankel, George A Carlson, Janet Rossant, Joseph H Nadeau, Monica J Justice.   

Abstract

A step towards annotating the mouse genome is to use forward genetics in phenotype-driven screens to saturate the genome with mutations. The purpose of this article is to highlight the new projects in North America that are focused on isolating mouse mutations after ENU mutagenesis and phenotype screening.

Entities:  

Mesh：

Substances：

Year:  2004        PMID： 15619961      PMCID： PMC3774779          DOI： 10.1007/s10709-004-1436-6

Source DB:  PubMed          Journal:  Genetica        ISSN： 0016-6707            Impact factor:   1.082


  32 in total

1.  MouseNet database: digital management of a large-scale mutagenesis project.

Authors:  W Pargent; S Heffner; K F Schäble; D Soewarto; H Fuchs; M Hrabé de Angelis
Journal:  Mamm Genome       Date:  2000-07       Impact factor: 2.957

2.  The large-scale Munich ENU-mouse-mutagenesis screen.

Authors:  D Soewarto; C Fella; A Teubner; B Rathkolb; W Pargent; S Heffner; S Marschall; E Wolf; R Balling; M Hrabé de Angelis
Journal:  Mamm Genome       Date:  2000-07       Impact factor: 2.957

3.  The clinical-chemical screen in the Munich ENU Mouse Mutagenesis Project: screening for clinically relevant phenotypes.

Authors:  B Rathkolb; T Decker; E Fuchs; D Soewarto; C Fella; S Heffner; W Pargent; R Wanke; R Balling; M Hrabé de Angelis; H J Kolb; E Wolf
Journal:  Mamm Genome       Date:  2000-07       Impact factor: 2.957

4.  Genome-wide, large-scale production of mutant mice by ENU mutagenesis.

Authors:  M H Hrabé de Angelis; H Flaswinkel; H Fuchs; B Rathkolb; D Soewarto; S Marschall; S Heffner; W Pargent; K Wuensch; M Jung; A Reis; T Richter; F Alessandrini; T Jakob; E Fuchs; H Kolb; E Kremmer; K Schaeble; B Rollinski; A Roscher; C Peters; T Meitinger; T Strom; T Steckler; F Holsboer; T Klopstock; F Gekeler; C Schindewolf; T Jung; K Avraham; H Behrendt; J Ring; A Zimmer; K Schughart; K Pfeffer; E Wolf; R Balling
Journal:  Nat Genet       Date:  2000-08       Impact factor: 38.330

5.  A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse.

Authors:  P M Nolan; J Peters; M Strivens; D Rogers; J Hagan; N Spurr; I C Gray; L Vizor; D Brooker; E Whitehill; R Washbourne; T Hough; S Greenaway; M Hewitt; X Liu; S McCormack; K Pickford; R Selley; C Wells; Z Tymowska-Lalanne; P Roby; P Glenister; C Thornton; C Thaung; J A Stevenson; R Arkell; P Mburu; R Hardisty; A Kiernan; A Erven; K P Steel; S Voegeling; J L Guenet; C Nickols; R Sadri; M Nasse; A Isaacs; K Davies; M Browne; E M Fisher; J Martin; S Rastan; S D Brown; J Hunter
Journal:  Nat Genet       Date:  2000-08       Impact factor: 38.330

Review 6.  Genetics of the mammalian circadian system: Photic entrainment, circadian pacemaker mechanisms, and posttranslational regulation.

Authors:  P L Lowrey; J S Takahashi
Journal:  Annu Rev Genet       Date:  2000       Impact factor: 16.830

7.  Course of renal injury in the Mpv17-deficient transgenic mouse.

Authors:  Thomas O'Bryan; Hans Weiher; Helmut G Rennke; Stefan Kren; Thomas H Hostetter
Journal:  J Am Soc Nephrol       Date:  2000-06       Impact factor: 10.121

Review 8.  Altered fear circuits in 5-HT(1A) receptor KO mice.

Authors:  C Gross; L Santarelli; D Brunner; X Zhuang; R Hen
Journal:  Biol Psychiatry       Date:  2000-12-15       Impact factor: 13.382

9.  Long-term prevention of renal insufficiency, excess matrix gene expression, and glomerular mesangial matrix expansion by treatment with monoclonal antitransforming growth factor-beta antibody in db/db diabetic mice.

Authors:  F N Ziyadeh; B B Hoffman; D C Han; M C Iglesias-De La Cruz; S W Hong; M Isono; S Chen; T A McGowan; K Sharma
Journal:  Proc Natl Acad Sci U S A       Date:  2000-07-05       Impact factor: 11.205

10.  Implementation of a large-scale ENU mutagenesis program: towards increasing the mouse mutant resource.

Authors:  P M Nolan; J Peters; L Vizor; M Strivens; R Washbourne; T Hough; C Wells; P Glenister; C Thornton; J Martin; E Fisher; D Rogers; J Hagan; C Reavill; I Gray; J Wood; N Spurr; M Browne; S Rastan; J Hunter; S D Brown
Journal:  Mamm Genome       Date:  2000-07       Impact factor: 2.957
View more
  38 in total

Review 1.  Chemical mutagenesis: a new strategy against the global threat of infectious diseases.

Authors:  Etienne Richer; Salman T Qureshi; Silvia M Vidal; Danielle Malo
Journal:  Mamm Genome       Date:  2008-06-17       Impact factor: 2.957

2.  From ENU mutagenesis to population genetics.

Authors:  N Avrion Mitchison; Bryan Clarke
Journal:  Mamm Genome       Date:  2008-03-26       Impact factor: 2.957

3.  Training mouse pathologists: 15 years of workshops on the pathology of mouse models of human disease.

Authors:  John P Sundberg; Kelli Boyd; Harm Hogenesch; Alexander Y Nikitin; Piper M Treuting; Jerrold M Ward
Journal:  Lab Anim (NY)       Date:  2017-04-19       Impact factor: 12.625

Review 4.  Controlling complexity: the clinical relevance of mouse complex genetics.

Authors:  Klaus Schughart; Claude Libert; Martien J Kas
Journal:  Eur J Hum Genet       Date:  2013-05-01       Impact factor: 4.246

Review 5.  Do Gametes Woo? Evidence for Their Nonrandom Union at Fertilization.

Authors:  Joseph H Nadeau
Journal:  Genetics       Date:  2017-10       Impact factor: 4.562

6.  An ENU-induced recessive mutation in Mpl leads to thrombocytopenia with overdominance.

Authors:  E Ricky Chan; Heather Lavender; Geqiang Li; Peter Haviernik; Kevin D Bunting; Mark D Adams
Journal:  Exp Hematol       Date:  2008-12-06       Impact factor: 3.084

7.  Automated assessment of pavlovian conditioned freezing and shock reactivity in mice using the video freeze system.

Authors:  Stephan G Anagnostaras; Suzanne C Wood; Tristan Shuman; Denise J Cai; Arthur D Leduc; Karl R Zurn; J Brooks Zurn; Jennifer R Sage; Gerald M Herrera
Journal:  Front Behav Neurosci       Date:  2010-09-30       Impact factor: 3.558

8.  A novel mutation in Prph2, a gene regulated by Nr2e3, causes retinal degeneration and outer-segment defects similar to Nr2e3 ( rd7/rd7 ) retinas.

Authors:  Arne M Nystuen; Andrew J Sachs; Yang Yuan; Laura Heuermann; Neena B Haider
Journal:  Mamm Genome       Date:  2008-09-03       Impact factor: 2.957

9.  An N-ethyl-N-nitrosourea mutagenesis recessive screen identifies two candidate regions for murine cardiomyopathy that map to chromosomes 1 and 15.

Authors:  Liliana Fernandez; Douglas A Marchuk; Jennifer L Moran; David R Beier; Howard A Rockman
Journal:  Mamm Genome       Date:  2009-04-23       Impact factor: 2.957

Review 10.  Mouse models of cataract.

Authors:  Jochen Graw
Journal:  J Genet       Date:  2009-12       Impact factor: 1.166
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.