Literature DB >> 15610697

Stem cells: implications for urology.

Kirk C Lo1, Shannon Whirledge, Dolores J Lamb.   

Abstract

Stem cells are characterized by their potential immortality and are capable of self-renewal and differentiation. Stem cells are proposed to provide the potential to cure degenerative diseases and to give important clues regarding human development and aging. However, stem cell research has evoked enthusiasm and passionate debate regarding the ethics of their use in medicine and reproduction. In this article, the current understanding of the biology of stem cells, their application in urology, and some of the controversies regarding their use are discussed. Although the clinical application of stem cell technologies to urologic practice is likely to be well in the future, advances in this field hold great promise for the correction of a number of illnesses. Nevertheless, scientists and ethicists will continue to struggle with their ethical responsibilities to the patient and society.

Entities:  

Mesh:

Year:  2005        PMID: 15610697     DOI: 10.1007/s11934-005-0067-5

Source DB:  PubMed          Journal:  Curr Urol Rep        ISSN: 1527-2737            Impact factor:   3.092


  40 in total

Review 1.  Embryonic stem cells as an in vitro model for mutagenicity, cytotoxicity and embryotoxicity studies: present state and future prospects.

Authors:  J Rohwedel; K Guan; C Hegert; A M Wobus
Journal:  Toxicol In Vitro       Date:  2001-12       Impact factor: 3.500

2.  "Stemness": transcriptional profiling of embryonic and adult stem cells.

Authors:  Miguel Ramalho-Santos; Soonsang Yoon; Yumi Matsuzaki; Richard C Mulligan; Douglas A Melton
Journal:  Science       Date:  2002-09-12       Impact factor: 47.728

3.  A direct measurement of the radiation sensitivity of normal mouse bone marrow cells.

Authors:  J E TILL; E A McCULLOCH
Journal:  Radiat Res       Date:  1961-02       Impact factor: 2.841

Review 4.  Tissue engineering, stem cells, and cloning: opportunities for regenerative medicine.

Authors:  Chester J Koh; Anthony Atala
Journal:  J Am Soc Nephrol       Date:  2004-05       Impact factor: 10.121

5.  Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets.

Authors:  N Lumelsky; O Blondel; P Laeng; I Velasco; R Ravin; R McKay
Journal:  Science       Date:  2001-04-26       Impact factor: 47.728

6.  Establishment in culture of pluripotential cells from mouse embryos.

Authors:  M J Evans; M H Kaufman
Journal:  Nature       Date:  1981-07-09       Impact factor: 49.962

7.  A stem cell molecular signature.

Authors:  Natalia B Ivanova; John T Dimos; Christoph Schaniel; Jason A Hackney; Kateri A Moore; Ihor R Lemischka
Journal:  Science       Date:  2002-09-12       Impact factor: 47.728

8.  Embryonic stem cells can form germ cells in vitro.

Authors:  Yayoi Toyooka; Naoki Tsunekawa; Ryuko Akasu; Toshiaki Noce
Journal:  Proc Natl Acad Sci U S A       Date:  2003-09-22       Impact factor: 11.205

9.  Spermatogenesis following male germ-cell transplantation.

Authors:  R L Brinster; J W Zimmermann
Journal:  Proc Natl Acad Sci U S A       Date:  1994-11-22       Impact factor: 11.205

10.  Embryonic stem cell lines derived from human blastocysts.

Authors:  J A Thomson; J Itskovitz-Eldor; S S Shapiro; M A Waknitz; J J Swiergiel; V S Marshall; J M Jones
Journal:  Science       Date:  1998-11-06       Impact factor: 47.728

View more
  3 in total

1.  Expression of monocyte chemotactic protein 3 following simulated birth trauma in a murine model of obesity.

Authors:  Gino J Vricella; Mingfang Tao; Cengiz Z Altuntas; Guiming Liu; Michael Kavran; Firouz Daneshgari; Adonis K Hijaz
Journal:  Urology       Date:  2010-10-23       Impact factor: 2.649

Review 2.  Possible therapeutic use of spermatogonial stem cells in the treatment of male infertility: a brief overview.

Authors:  Slobodan Vlajković; Rade Cukuranović; Marija Daković Bjelaković; Vladisav Stefanović
Journal:  ScientificWorldJournal       Date:  2012-03-12

3.  The histocompatibility research of hair follicle stem cells with bladder acellular matrix.

Authors:  Jia Li; Wenguang Wang; Jiuzhi Li; Mulati Rexiati; Henqing An; Feng Wang; Yujie Wang
Journal:  Medicine (Baltimore)       Date:  2016-11       Impact factor: 1.889

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.