Literature DB >> 12228720

"Stemness": transcriptional profiling of embryonic and adult stem cells.

Miguel Ramalho-Santos1, Soonsang Yoon, Yumi Matsuzaki, Richard C Mulligan, Douglas A Melton.   

Abstract

The transcriptional profiles of mouse embryonic, neural, and hematopoietic stem cells were compared to define a genetic program for stem cells. A total of 216 genes are enriched in all three types of stem cells, and several of these genes are clustered in the genome. When compared to differentiated cell types, stem cells express a significantly higher number of genes (represented by expressed sequence tags) whose functions are unknown. Embryonic and neural stem cells have many similarities at the transcriptional level. These results provide a foundation for a more detailed understanding of stem cell biology.

Entities:  

Mesh：

Substances：

Year:  2002        PMID： 12228720     DOI： 10.1126/science.1072530

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  486 in total

1.  A nucleolar mechanism controlling cell proliferation in stem cells and cancer cells.

Authors:  Robert Y L Tsai; Ronald D G McKay
Journal:  Genes Dev       Date:  2002-12-01       Impact factor: 11.361

2.  Gfer is a critical regulator of HSC proliferation.

Authors:  Uma Sankar; Anthony R Means
Journal:  Cell Cycle       Date:  2011-07-15       Impact factor: 4.534

3.  Perivascular human endometrial mesenchymal stem cells express pathways relevant to self-renewal, lineage specification, and functional phenotype.

Authors:  Trimble L B Spitzer; Angela Rojas; Zara Zelenko; Lusine Aghajanova; David W Erikson; Fatima Barragan; Michelle Meyer; John S Tamaresis; Amy E Hamilton; Juan C Irwin; Linda C Giudice
Journal:  Biol Reprod       Date:  2012-02-29       Impact factor: 4.285

4.  In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells.

Authors:  Gabriela Dontu; Wissam M Abdallah; Jessica M Foley; Kyle W Jackson; Michael F Clarke; Mari J Kawamura; Max S Wicha
Journal:  Genes Dev       Date:  2003-05-15       Impact factor: 11.361

5.  Defining the epithelial stem cell niche in skin.

Authors:  Tudorita Tumbar; Geraldine Guasch; Valentina Greco; Cedric Blanpain; William E Lowry; Michael Rendl; Elaine Fuchs
Journal:  Science       Date:  2003-12-11       Impact factor: 47.728

6.  Transcription enhancer factor 1 binds multiple muscle MEF2 and A/T-rich elements during fast-to-slow skeletal muscle fiber type transitions.

Authors:  Natalia Karasseva; Gretchen Tsika; Juan Ji; Aijing Zhang; Xiaoqing Mao; Richard Tsika
Journal:  Mol Cell Biol       Date:  2003-08       Impact factor: 4.272

Review 7.  Advancing insights into stem cell niche complexities with next-generation technologies.

Authors:  Nicholas Heitman; Nivedita Saxena; Michael Rendl
Journal:  Curr Opin Cell Biol       Date:  2018-07-19       Impact factor: 8.382

8.  Gene expression profiling of granulosa cells from PCOS patients following varying doses of human chorionic gonadotropin.

Authors:  Serdar Coskun; Hasan H Otu; Khalid A Awartani; Laila A Al-Alwan; Saad Al-Hassan; Hend Al-Mayman; Namik Kaya; Mehmet S Inan
Journal:  J Assist Reprod Genet       Date:  2013-02-05       Impact factor: 3.412

9.  ZFX regulates glioma cell proliferation and survival in vitro and in vivo.

Authors:  Zhichuan Zhu; Kui Li; Dafeng Xu; Yongjie Liu; Hailiang Tang; Qing Xie; Liqian Xie; Jiwei Liu; Hongtao Wang; Ye Gong; Zelan Hu; Jing Zheng
Journal:  J Neurooncol       Date:  2013-01-16       Impact factor: 4.130

10.  Gene expression patterns in human embryonic stem cells and human pluripotent germ cell tumors.

Authors:  Jamie M Sperger; Xin Chen; Jonathan S Draper; Jessica E Antosiewicz; Chris H Chon; Sunita B Jones; James D Brooks; Peter W Andrews; Patrick O Brown; James A Thomson
Journal:  Proc Natl Acad Sci U S A       Date:  2003-10-31       Impact factor: 11.205
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.