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Literature DB >> 15602596

Detection of single base mismatches and abasic sites using phenanthridinium as an artificial DNA base and charge donor.

Linda Valis¹, Nicole Amann, Hans-Achim Wagenknecht.

Abstract

Combining the fluorescence properties of phenanthridinium as an artificial DNA base together with DNA-mediated charge transfer processes allows the homogeneous detection of DNA base mismatches and abasic sites.

Entities: Chemical Species

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Year: 2004 PMID： 15602596 DOI： 10.1039/b414672g

Source DB: PubMed Journal: Org Biomol Chem ISSN： 1477-0520 Impact factor: 3.876

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Cited

9 in total

1. Fluorescent nucleoside analogue displays enhanced emission upon pairing with guanine.

Authors: Yun Xie; Tucker Maxson; Yitzhak Tor
Journal: Org Biomol Chem Date: 2010-09-23 Impact factor: 3.876

2. Base pair motions control the rates and distance dependencies of reductive and oxidative DNA charge transfer.

Authors: Linda Valis; Qiang Wang; Milen Raytchev; Ivan Buchvarov; Hans-Achim Wagenknecht; Torsten Fiebig
Journal: Proc Natl Acad Sci U S A Date: 2006-06-26 Impact factor: 11.205

3. Synthesis and properties of size-expanded DNAs: toward designed, functional genetic systems.

Authors: Andrew T Krueger; Haige Lu; Alex H F Lee; Eric T Kool
Journal: Acc Chem Res Date: 2007-02 Impact factor: 22.384

4. A highly emissive fluorescent nucleoside that signals the activity of toxic ribosome-inactivating proteins.

Authors: Seergazhi G Srivatsan; Nicholas J Greco; Yitzhak Tor
Journal: Angew Chem Int Ed Engl Date: 2008 Impact factor: 15.336

Review 5. DNA-multichromophore systems.

Authors: Yin Nah Teo; Eric T Kool
Journal: Chem Rev Date: 2012-03-16 Impact factor: 60.622

Detection of single base mismatches and abasic sites using phenanthridinium as an artificial DNA base and charge donor.

1. Fluorescent nucleoside analogue displays enhanced emission upon pairing with guanine.

2. Base pair motions control the rates and distance dependencies of reductive and oxidative DNA charge transfer.

3. Synthesis and properties of size-expanded DNAs: toward designed, functional genetic systems.

4. A highly emissive fluorescent nucleoside that signals the activity of toxic ribosome-inactivating proteins.

Review 5. DNA-multichromophore systems.

6. A highly fluorescent nucleoside analog based on thieno[3,4-d]pyrimidine senses mismatched pairing.

7. Synthesis of novel MMT/acyl-protected nucleo alanine monomers for the preparation of DNA/alanyl-PNA chimeras.

8. Sensitivity of Ru(bpy)2dppz2+ luminescence to DNA defects.

Review 9. Come-back of phenanthridine and phenanthridinium derivatives in the 21st century.