Literature DB >> 15588026

Unusual C21 linear polyacetylenic alcohols from an Atlantic ascidian.

Margherita Gavagnin1, Francesco Castelluccio, Angelo Antonelli, Josè Templado, Guido Cimino.   

Abstract

Four novel straight-chain polyacetylenic alcohols were isolated from a marine ascidian (Phylum Chordata, subphyllum Urochordata) collected off Vigo, along the Atlantic coast of northwestern Spain. The chemical structures, which exhibit an uncommon dienyne group, were characterized by spectroscopic methods, mainly mono- and bi-dimensional NMR. This is the first finding of acetylenic lipids from an organism belonging to phylum Chordata.

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Year:  2004        PMID： 15588026     DOI： 10.1007/s11745-004-1282-7

Source DB:  PubMed          Journal:  Lipids        ISSN： 0024-4201            Impact factor:   1.880


  5 in total

1.  Brominated polyacetylenic acids from the marine sponge Xestospongia muta: inhibitors of HIV protease.

Authors:  A D Patil; W C Kokke; S Cochran; T A Francis; T Tomszek; J W Westley
Journal:  J Nat Prod       Date:  1992-09       Impact factor: 4.050

Review 2.  Marine natural products.

Authors:  John W Blunt; Brent R Copp; Murray H G Munro; Peter T Northcote; Michèle R Prinsep
Journal:  Nat Prod Rep       Date:  2004-01-14       Impact factor: 13.423

3.  Cytotoxic polyacetylenes from the marine sponge Petrosia sp.

Authors:  J S Kim; Y J Lim; K S Im; J H Jung; C J Shim; C O Lee; J Hong; H Lee
Journal:  J Nat Prod       Date:  1999-04       Impact factor: 4.050

4.  Additional cytotoxic polyacetylenes from the marine sponge Petrosia species.

Authors:  Y J Lim; H S Park; K S Im; C Lee; J Hong; M Lee; D Kim Dk; J H Jung
Journal:  J Nat Prod       Date:  2001-01       Impact factor: 4.050

5.  Corticatic acids A-C, antifungal acetylenic acids from the marine sponge, Petrosia corticata.

Authors:  H Y Li; S Matsunaga; N Fusetani
Journal:  J Nat Prod       Date:  1994-10       Impact factor: 4.050
  5 in total
  2 in total

Review 1.  Anticancer activity of natural and synthetic acetylenic lipids.

Authors:  Valery M Dembitsky
Journal:  Lipids       Date:  2006-10       Impact factor: 1.880

Review 2.  Biosynthesis and function of polyacetylenes and allied natural products.

Authors:  Robert E Minto; Brenda J Blacklock
Journal:  Prog Lipid Res       Date:  2008-03-13       Impact factor: 16.195
  2 in total

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