Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 In vitro interactions between antifungals and immunosuppressants against Aspergillus fumigatus isolates from transplant and nontransplant patients.

Literature DB >> 15561883

In vitro interactions between antifungals and immunosuppressants against Aspergillus fumigatus isolates from transplant and nontransplant patients.

William J Steinbach¹, Nina Singh, Jackie L Miller, Daniel K Benjamin, Wiley A Schell, Joseph Heitman, John R Perfect.

Abstract

We performed in vitro antifungal checkerboard testing on 12 Aspergillus fumigatus clinical isolates (6 transplant recipients and 6 nontransplant patients) with three antifungal agents (amphotericin B, voriconazole, and caspofungin) and three immunosuppressants (FK506, cyclosporine, and rapamycin). We were not able to detect a difference in calcineurin inhibitor antifungal activity against isolates from transplant recipients and nontransplant patients.

Entities: Chemical Gene Species

Mesh：

Substances：

Year: 2004 PMID： 15561883 PMCID： PMC529228 DOI： 10.1128/AAC.48.12.4922-4925.2004

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

30 in total

1. Comparison of the roles of calcineurin in physiology and virulence in serotype D and serotype A strains of Cryptococcus neoformans.

Authors: M C Cruz; R A Sia; M Olson; G M Cox; J Heitman
Journal: Infect Immun Date: 2000-02 Impact factor: 3.441

Review 2. Invasive aspergillosis.

Authors: D W Denning
Journal: Clin Infect Dis Date: 1998-04 Impact factor: 9.079

3. Calcineurin is required for virulence of Cryptococcus neoformans.

Authors: A Odom; S Muir; E Lim; D L Toffaletti; J Perfect; J Heitman
Journal: EMBO J Date: 1997-05-15 Impact factor: 11.598

4. Synergistic antifungal activities of bafilomycin A(1), fluconazole, and the pneumocandin MK-0991/caspofungin acetate (L-743,873) with calcineurin inhibitors FK506 and L-685,818 against Cryptococcus neoformans.

Authors: M Del Poeta; M C Cruz; M E Cardenas; J R Perfect; J Heitman
Journal: Antimicrob Agents Chemother Date: 2000-03 Impact factor: 5.191

5. Effects of methylprednisolone and cyclosporine A on fungal growth in vitro.

Authors: N P Bell; C L Karp; E C Alfonso; J Schiffman; D Miller
Journal: Cornea Date: 1999-05 Impact factor: 2.651

6. Potent synergism of the combination of fluconazole and cyclosporine in Candida albicans.

Authors: O Marchetti; P Moreillon; M P Glauser; J Bille; D Sanglard
Journal: Antimicrob Agents Chemother Date: 2000-09 Impact factor: 5.191

7. In vitro susceptibility testing methods for caspofungin against Aspergillus and Fusarium isolates.

Authors: S Arikan; M Lozano-Chiu; V Paetznick; J H Rex
Journal: Antimicrob Agents Chemother Date: 2001-01 Impact factor: 5.191

8. Immunosuppressive and nonimmunosuppressive cyclosporine analogs are toxic to the opportunistic fungal pathogen Cryptococcus neoformans via cyclophilin-dependent inhibition of calcineurin.

Authors: M C Cruz; M Del Poeta; P Wang; R Wenger; G Zenke; V F Quesniaux; N R Movva; J R Perfect; M E Cardenas; J Heitman
Journal: Antimicrob Agents Chemother Date: 2000-01 Impact factor: 5.191

9. Fluconazole plus cyclosporine: a fungicidal combination effective against experimental endocarditis due to Candida albicans.

Authors: O Marchetti; J M Entenza; D Sanglard; J Bille; M P Glauser; P Moreillon
Journal: Antimicrob Agents Chemother Date: 2000-11 Impact factor: 5.191

Review 10. Antifungal activities of antineoplastic agents: Saccharomyces cerevisiae as a model system to study drug action.

Authors: M E Cardenas; M C Cruz; M Del Poeta; N Chung; J R Perfect; J Heitman
Journal: Clin Microbiol Rev Date: 1999-10 Impact factor: 26.132

23 in total

1. Calcineurin inhibitor agents interact synergistically with antifungal agents in vitro against Cryptococcus neoformans isolates: correlation with outcome in solid organ transplant recipients with cryptococcosis.

Authors: Dimitrios P Kontoyiannis; Russell E Lewis; Barbara D Alexander; Olivier Lortholary; Françoise Dromer; Krishan L Gupta; George T John; Ramon Del Busto; Goran B Klintmalm; Jyoti Somani; G Marshall Lyon; Kenneth Pursell; Valentina Stosor; Patricia Munoz; Ajit P Limaye; Andre C Kalil; Timothy L Pruett; Julia Garcia-Diaz; Atul Humar; Sally Houston; Andrew A House; Dannah Wray; Susan Orloff; Lorraine A Dowdy; Robert A Fisher; Joseph Heitman; Nathaniel D Albert; Marilyn M Wagener; Nina Singh
Journal: Antimicrob Agents Chemother Date: 2007-12-10 Impact factor: 5.191

2. In vitro interactions between antifungals and immunosuppressive drugs against zygomycetes.

Authors: Eric Dannaoui; Patrick Schwarz; Olivier Lortholary
Journal: Antimicrob Agents Chemother Date: 2009-05-18 Impact factor: 5.191

Review 3. Stress, drugs, and evolution: the role of cellular signaling in fungal drug resistance.

Authors: Leah E Cowen; William J Steinbach
Journal: Eukaryot Cell Date: 2008-03-28

4. Paradoxical effect of caspofungin against Candida bloodstream isolates is mediated by multiple pathways but eliminated in human serum.

Authors: Ryan K Shields; M Hong Nguyen; Chen Du; Ellen Press; Shaoji Cheng; Cornelius J Clancy
Journal: Antimicrob Agents Chemother Date: 2011-03-21 Impact factor: 5.191

5. Systems-level antimicrobial drug and drug synergy discovery.

Authors: Terry Roemer; Charles Boone
Journal: Nat Chem Biol Date: 2013-04 Impact factor: 15.040

Review 6. Direct effects of non-antifungal agents used in cancer chemotherapy and organ transplantation on the development and virulence of Candida and Aspergillus species.

Authors: Sharon C-A Chen; Russell E Lewis; Dimitrios P Kontoyiannis
Journal: Virulence Date: 2011-07-01 Impact factor: 5.882