Literature DB >> 18070977

Calcineurin inhibitor agents interact synergistically with antifungal agents in vitro against Cryptococcus neoformans isolates: correlation with outcome in solid organ transplant recipients with cryptococcosis.

Dimitrios P Kontoyiannis1, Russell E Lewis, Barbara D Alexander, Olivier Lortholary, Françoise Dromer, Krishan L Gupta, George T John, Ramon Del Busto, Goran B Klintmalm, Jyoti Somani, G Marshall Lyon, Kenneth Pursell, Valentina Stosor, Patricia Munoz, Ajit P Limaye, Andre C Kalil, Timothy L Pruett, Julia Garcia-Diaz, Atul Humar, Sally Houston, Andrew A House, Dannah Wray, Susan Orloff, Lorraine A Dowdy, Robert A Fisher, Joseph Heitman, Nathaniel D Albert, Marilyn M Wagener, Nina Singh.   

Abstract

Synergistic interactions were observed between CIs and antifungal agents against 53 (90%) of 59 Cryptococcus neoformans isolates from solid organ transplant recipients with cryptococcosis and may account for better outcomes in patients with cryptococcosis receiving these immunosuppressive agents.

Entities:  

Mesh：

Substances：

Year:  2007        PMID： 18070977      PMCID： PMC2224743          DOI： 10.1128/AAC.00990-07

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  23 in total

1.  Comparison of the roles of calcineurin in physiology and virulence in serotype D and serotype A strains of Cryptococcus neoformans.

Authors:  M C Cruz; R A Sia; M Olson; G M Cox; J Heitman
Journal:  Infect Immun       Date:  2000-02       Impact factor: 3.441

Review 2.  Immune reconstitution syndrome associated with opportunistic mycoses.

Authors:  Nina Singh; John R Perfect
Journal:  Lancet Infect Dis       Date:  2007-06       Impact factor: 25.071

3.  Antifungal susceptibility of Cryptococcus neoformans isolates in HIV-infected patients to fluconazole, itraconazole and voriconazole in Spain: 1994-1996 and 1997-2005.

Authors:  A I Aller; R Claro; C Castro; C Serrano; M F Colom; E Martín-Mazuelos
Journal:  Chemotherapy       Date:  2007-05-10       Impact factor: 2.544

4.  Results obtained with various antifungal susceptibility testing methods do not predict early clinical outcome in patients with cryptococcosis.

Authors:  E Dannaoui; M Abdul; M Arpin; A Michel-Nguyen; M A Piens; A Favel; O Lortholary; F Dromer
Journal:  Antimicrob Agents Chemother       Date:  2006-07       Impact factor: 5.191

5.  Synergistic antifungal activities of bafilomycin A(1), fluconazole, and the pneumocandin MK-0991/caspofungin acetate (L-743,873) with calcineurin inhibitors FK506 and L-685,818 against Cryptococcus neoformans.

Authors:  M Del Poeta; M C Cruz; M E Cardenas; J R Perfect; J Heitman
Journal:  Antimicrob Agents Chemother       Date:  2000-03       Impact factor: 5.191

6.  The TOR signaling cascade regulates gene expression in response to nutrients.

Authors:  M E Cardenas; N S Cutler; M C Lorenz; C J Di Como; J Heitman
Journal:  Genes Dev       Date:  1999-12-15       Impact factor: 11.361

7.  Potent synergism of the combination of fluconazole and cyclosporine in Candida albicans.

Authors:  O Marchetti; P Moreillon; M P Glauser; J Bille; D Sanglard
Journal:  Antimicrob Agents Chemother       Date:  2000-09       Impact factor: 5.191

8.  Quality control limits for broth microdilution susceptibility tests of ten antifungal agents.

Authors:  A L Barry; M A Pfaller; S D Brown; A Espinel-Ingroff; M A Ghannoum; C Knapp; R P Rennie; J H Rex; M G Rinaldi
Journal:  J Clin Microbiol       Date:  2000-09       Impact factor: 5.948

9.  Identification and characterization of a highly conserved calcineurin binding protein, CBP1/calcipressin, in Cryptococcus neoformans.

Authors:  J Görlach; D S Fox; N S Cutler; G M Cox; J R Perfect; J Heitman
Journal:  EMBO J       Date:  2000-07-17       Impact factor: 11.598

10.  Combination of voriconazole and caspofungin as primary therapy for invasive aspergillosis in solid organ transplant recipients: a prospective, multicenter, observational study.

Authors:  Nina Singh; Ajit P Limaye; Graeme Forrest; Nasia Safdar; Patricia Muñoz; Kenneth Pursell; Sally Houston; Fernando Rosso; Jose G Montoya; Pamela Patton; Ramon Del Busto; Jose M Aguado; Robert A Fisher; Goran B Klintmalm; Rachel Miller; Marilyn M Wagener; Russell E Lewis; Dimitrios P Kontoyiannis; Shahid Husain
Journal:  Transplantation       Date:  2006-02-15       Impact factor: 4.939
View more
  29 in total

1.  In vitro interactions between antifungals and immunosuppressive drugs against zygomycetes.

Authors:  Eric Dannaoui; Patrick Schwarz; Olivier Lortholary
Journal:  Antimicrob Agents Chemother       Date:  2009-05-18       Impact factor: 5.191

Review 2.  Cryptococcal meningitis: epidemiology, immunology, diagnosis and therapy.

Authors:  Peter R Williamson; Joseph N Jarvis; Anil A Panackal; Matthew C Fisher; Síle F Molloy; Angela Loyse; Thomas S Harrison
Journal:  Nat Rev Neurol       Date:  2016-11-25       Impact factor: 42.937

3.  Cryptococcosis and cryptococcal meningitis: New predictors and clinical outcomes at a United States academic medical centre.

Authors:  Bahar H Kashef Hamadani; Carlos Franco-Paredes; Bruce McCollister; Leland Shapiro; J David Beckham; Andrés F Henao-Martínez
Journal:  Mycoses       Date:  2018-01-23       Impact factor: 4.377

Review 4.  Functional diversity and pharmacological profiles of the FKBPs and their complexes with small natural ligands.

Authors:  Andrzej Galat
Journal:  Cell Mol Life Sci       Date:  2012-12-08       Impact factor: 9.261

Review 5.  Signaling cascades as drug targets in model and pathogenic fungi.

Authors:  Robert J Bastidas; Jennifer L Reedy; Helena Morales-Johansson; Joseph Heitman; Maria E Cardenas
Journal:  Curr Opin Investig Drugs       Date:  2008-08

6.  Approaches to antifungal therapies and their effectiveness among patients with cryptococcosis.

Authors:  Emily W Bratton; Nada El Husseini; Cody A Chastain; Michael S Lee; Charles Poole; Til Stürmer; David J Weber; Jonathan J Juliano; John R Perfect
Journal:  Antimicrob Agents Chemother       Date:  2013-03-11       Impact factor: 5.191

7.  In vitro interactions of calcineurin inhibitors with conventional antifungal agents against the yeast form of Penicillium marneffei.

Authors:  Dongdong Mo; Xin Li; Lili Wei; Chenghang Sun; Hao Liang; Cunwei Cao
Journal:  Mycopathologia       Date:  2014-07-23       Impact factor: 2.574

Review 8.  Cryptococcosis in solid organ transplant recipients: current state of the science.

Authors:  Nina Singh; Francoise Dromer; John R Perfect; Olivier Lortholary
Journal:  Clin Infect Dis       Date:  2008-11-15       Impact factor: 9.079

9.  Predictors of immune reconstitution syndrome in organ transplant recipients with cryptococcosis: implications for the management of immunosuppression.

Authors:  Hsin-Yun Sun; Barbara D Alexander; Shirish Huprikar; Graeme N Forrest; Didier Bruno; G Marshall Lyon; Dannah Wray; Leonard B Johnson; Costi D Sifri; Raymund R Razonable; Michele I Morris; Valentina Stosor; Marilyn M Wagener; Nina Singh
Journal:  Clin Infect Dis       Date:  2014-09-09       Impact factor: 9.079

10.  Neurological complications of solid organ transplantation.

Authors:  Amy A Pruitt; Francesc Graus; Myrna R Rosenfeld
Journal:  Neurohospitalist       Date:  2013-07
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.