| Literature DB >> 15556410 |
Christopher T Calderone1, David R Liu.
Abstract
The translation of nucleic acids into synthetic structures with expanded functional potential has been the subject of considerable research, with applications including small-molecule and polymer evolution, reaction discovery and sensing. Here, we review properties of nucleic-acid-templated synthesis in the context of requirements for prebiotic translation. This analysis highlights the chemical possibilities of ancient translation systems, as well as challenges that these systems may have faced.Entities:
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Year: 2004 PMID： 15556410 DOI： 10.1016/j.cbpa.2004.09.003
Source DB: PubMed Journal: Curr Opin Chem Biol ISSN： 1367-5931 Impact factor: 8.822