Literature DB >> 15549484

Implant removal for late-developing infection after instrumented posterior spinal fusion for scoliosis: reinstrumentation reduces loss of correction. A retrospective analysis of 45 cases.

Michael Muschik1, Wiebke Lück, Dietrich Schlenzka.   

Abstract

A retrospective follow-up study of patients who, having undergone instrumented posterior spinal fusion for scoliosis, experienced late infection and then underwent either implant removal alone or implant removal and instrumented refusion. We conducted this study to determine whether it is possible to avoid loss of correction by a single-stage implant removal and reinstrumentation procedure. There have been a few reports of late-appearing infections after spinal instrumentation. Implant bulk, metallurgic reactions, and contamination with low-virulence microorganisms have been suggested as possible etiologic factors. The clinical symptoms include pain, swelling, redness, and spontaneous drainage of fluid. Complete instrumentation removal and systemic antibiotics is usually curative. We retrospectively reviewed 45 patients who underwent instrumented posterior spinal fusion for scoliosis and experienced development of late infections and, after a mean of 3 years after the initial procedure, either underwent implant removal alone [ n=35, instrumentation removal (HR) group] or additionally underwent reinstrumentation and fusion [ n=10, reinstrumentation and fusion (RI&F) group]. Three patients were reinstrumented 1.5 years after instrumentation removal, and seven underwent a one-stage rod removal and reinstrumentation/refusion procedure. Allergic predisposition, protracted postoperative fever, and pseudarthrosis appear to increase the risk of late-developing infection after posterior spinal fusion. All wounds in both groups healed uneventfully. Preoperative radiographic Cobb measurements showed no statistically significant between-group differences. At follow-up, however, outcome was clearly better in the RI&F group: Loss of correction was significantly smaller in reinstrumented patients. Thus, the thoracic Cobb angle was 28+/-16 degrees (range 0-55 degrees ) in the RI&F group versus 42+/-15 degrees (21-80 degrees ) in the HR group, and the lumbar Cobb angle was 22+/-11 degrees (10-36 degrees ) in the RI&F group versus 29+/-12 degrees (13-54 degrees ) in the HR group. The results of our study demonstrate that wound healing is usually uneventful after instrumentation removal for late infection, also when patients undergo instrumented refusion in a one-stage procedure. Reinstrumentation appears to achieve permanent correction of scoliosis.

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Year:  2004        PMID: 15549484      PMCID: PMC3476652          DOI: 10.1007/s00586-004-0694-4

Source DB:  PubMed          Journal:  Eur Spine J        ISSN: 0940-6719            Impact factor:   3.134


  11 in total

1.  Late-developing infection in instrumented idiopathic scoliosis.

Authors:  C E Clark; H L Shufflebarger
Journal:  Spine (Phila Pa 1976)       Date:  1999-09-15       Impact factor: 3.468

2.  Comparison of long-term functional and radiologic outcomes after Harrington instrumentation and spondylodesis in adolescent idiopathic scoliosis: a review of 78 patients.

Authors:  Ilkka Helenius; Ville Remes; Timo Yrjönen; Mauno Ylikoski; Dietrich Schlenzka; Miia Helenius; Mikko Poussa
Journal:  Spine (Phila Pa 1976)       Date:  2002-01-15       Impact factor: 3.468

3.  Late presentation of infection as a complication of Dwyer anterior spinal instrumentation.

Authors:  P A Robertson; T K Taylor
Journal:  J Spinal Disord       Date:  1993-06

4.  Dorsal instrumentation for idiopathic adolescent thoracic scoliosis: rod rotation versus translation.

Authors:  M Muschik; D Schlenzka; P N Robinson; C Kupferschmidt
Journal:  Eur Spine J       Date:  1999       Impact factor: 3.134

5.  Delayed infections following posterior spinal instrumentation for the treatment of idiopathic scoliosis.

Authors:  B S Richards
Journal:  J Bone Joint Surg Am       Date:  1995-04       Impact factor: 5.284

6.  Direct-exchange arthroplasty for the treatment of infection after total hip replacement. An average ten-year follow-up.

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Journal:  J Bone Joint Surg Am       Date:  1998-07       Impact factor: 5.284

7.  Aseptic loosening after CD instrumentation in the treatment of scoliosis: a report about eight cases.

Authors:  C Wimmer; H Gluch
Journal:  J Spinal Disord       Date:  1998-10

8.  Management of deep infection of total hip replacement.

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9.  Operative treatment of adolescent idiopathic thoracic scoliosis. Harrington-DTT versus Cotrel-Dubousset instrumentation.

Authors:  D Schlenzka; M Poussa; M Muschik
Journal:  Clin Orthop Relat Res       Date:  1993-12       Impact factor: 4.176

10.  Morphology of scoliosis: three-dimensional evolution.

Authors:  R Perdriolle; J Vidal
Journal:  Orthopedics       Date:  1987-06       Impact factor: 1.390

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  29 in total

Review 1.  Infections associated with spinal implants.

Authors:  Andrew Quaile
Journal:  Int Orthop       Date:  2012-01-08       Impact factor: 3.075

Review 2.  Engineering approaches for the detection and control of orthopaedic biofilm infections.

Authors:  Garth D Ehrlich; Paul Stoodley; Sandeep Kathju; Yongjun Zhao; Bruce R McLeod; Naomi Balaban; Fen Ze Hu; Nicholas G Sotereanos; J William Costerton; Philip S Stewart; J Christopher Post; Qiao Lin
Journal:  Clin Orthop Relat Res       Date:  2005-08       Impact factor: 4.176

3.  Metal levels in corrosion of spinal implants.

Authors:  Javier del Rio; Jose Beguiristain; Julio Duart
Journal:  Eur Spine J       Date:  2007-01-26       Impact factor: 3.134

4.  The follow-up of patients with postoperative infection of the spine.

Authors:  C Barrey; O Launay; E Freitas; F Michel; F Laurent; C Chidiac; G Perrin; T Ferry
Journal:  Eur J Orthop Surg Traumatol       Date:  2013-05-28

5.  The utility of erythrocyte sedimentation rate values and white blood cell counts after spinal deformity surgery in the early (≤3 months) post-operative period.

Authors:  Margaret G Kuhn; Lawrence G Lenke; Keith H Bridwell; June C O'Donnell; Scott J Luhmann
Journal:  J Child Orthop       Date:  2012-03-09       Impact factor: 1.548

6.  Permanent implantation of antibiotic cement over exposed instrumentation eradicates deep spinal infection.

Authors:  Joseph L Laratta; Joseph M Lombardi; Jamal N Shillingford; Hemant P Reddy; Borys V Gvozdyev; Yong J Kim
Journal:  J Spine Surg       Date:  2018-06

7.  Wound conditioning by vacuum assisted closure (V.A.C.) in postoperative infections after dorsal spine surgery.

Authors:  Ludwig Labler; Marius Keel; Otmar Trentz; Michael Heinzelmann
Journal:  Eur Spine J       Date:  2006-07-12       Impact factor: 3.134

8.  Titanium granules pre-treated with hydrogen peroxide inhibit growth of bacteria associated with post-operative infections in spine surgery.

Authors:  Acke Ohlin; Emma Mattsson; Matthias Mörgelin; Julia R Davies; Gunnel Svensäter; Stéphane Corvec; Pentti Tengvall; Kristian Riesbeck
Journal:  Eur Spine J       Date:  2018-05-07       Impact factor: 3.134

Review 9.  Spinal metallosis: a systematic review.

Authors:  Yoni Goldenberg; Jin W Tee; Cesar M Salinas-La Rosa; Michael Murphy
Journal:  Eur Spine J       Date:  2016-01-05       Impact factor: 3.134

10.  The diagnosis and management of infection following instrumented spinal fusion.

Authors:  Iona Collins; James Wilson-MacDonald; George Chami; Will Burgoyne; P Vinayakam; Tony Berendt; Jeremy Fairbank
Journal:  Eur Spine J       Date:  2007-12-13       Impact factor: 3.134

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